Epibrassinolide

Product Name: Epibrassinolide
CAS No.: 78821-43-9
Chemical Name: Epibrassinolide
Synonyms: 24-EPIBRASSINOLIDE;Epibrassinolide;BP55;B1105;CS-1258;Epibrassinolide;Brassinolide,BR;24R-BRASSINOLIDE;4-Epicastasterone;EPIBRASSINOLIDE (EBI)
CBNumber: CB8361275
Molecular Formula: C28H48O6
Formula Weight: 480.68
MOL File: 78821-43-9.mol

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Epibrassinolide Property

Melting point:: 256°C
Boiling point:: 633.7±55.0 °C(Predicted)
Density: 1.141±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Solid
pka: 14.27±0.70(Predicted)
color: White to Off-White
InChIKey: LUGSJEJPERVCLF-AQWCSQKENA-N
SMILES: O1[C@H](C(C)[C@@H](O)[C@H](O)[C@H](C)C(C)C)C2[C@]3(C)C(CCC3)[C@@H](O)[C@@H](O)C2C2CC(=O)CC[C@]2([H])[C@@H]1C |&1:1,4,6,8,14,20,22,31,33,r|
EPA Substance Registry System: 3H-Benz[c]indeno[5,4-e]oxepin-3-one, 10-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]hexadecahydro-5,6-dihydroxy-7a,9a-dimethyl-, (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)- (78821-43-9)

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Safety

Risk Statements: 22-36/37/38
Safety Statements: 22-36/37/39-45
WGK Germany: 3
HS Code: 29372900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E1641
Product name: Epibrassinolide
Purity: ≥85%
Packaging: 2mg
Price: $148
Updated: 2025/07/31

Sigma-Aldrich

Product number: E1641
Product name: Epibrassinolide
Purity: ≥85%
Packaging: 10mg
Price: $543
Updated: 2025/07/31

Cayman Chemical

Product number: 20337
Product name: Epibrassinolide
Purity: ≥95%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 20337
Product name: Epibrassinolide
Purity: ≥95%
Packaging: 5mg
Price: $268
Updated: 2024/03/01

Cayman Chemical

Product number: 20337
Product name: Epibrassinolide
Purity: ≥95%
Packaging: 10mg
Price: $401
Updated: 2024/03/01

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Epibrassinolide Chemical Properties,Usage,Production

Description

Epibrassinolide is a brassinosteroid that can be isolated from various plants and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress. Epibrassinolide is also reported to be a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. It has also been shown to protect neuronal PC12 cells from 1-methyl-4-phenylpyridinium-induced oxidative stress and consequent apoptosis in dopaminergic neurons.

Chemical Properties

The solubility of epibrassinolide in ethanol and DMSO is approximately 3 mg/ml and approximately 5 mg/ml in DMF.

Chemical Properties

White Solid

Uses

A plant growth stimulant

Uses

Epibrassinolide has been used:

in Murashige and Skoog (MS) medium to study the cotyledon and shoot length response of Cappelle-Desprez (rht8) and RIL6 (Rht8) plants towards it
in callus-inducing medium for callus induction
to induce the expression of the gene leaf inclination 2 (LC2) in rice sampling

Definition

ChEBI: 24-epi-brassinolide is a 2alpha-hydroxy steroid, a 3alpha-hydroxy steroid, a 22-hydroxy steroid, a 23-hydroxy steroid and a brassinosteroid.

Metabolic pathway

Two isomeric metabolites, 25-b- and 26-b-D- glucopyranosyloxy-24-epi-brassinolides, are formed in tomato cell suspension cultures with endogenously applied 24-epi-brassinolide. The two-step metabolic process involves hydroxylation of the side chain at C25 and C26, respectively, followed by glucosidation of the newly formed hydroxyl groups. The ratio between both metabolites is altered by in vivo treatment of the cell cultures with various cytochrome P-450-specific inhibitors, indicating the involvement of two different enzyme systems. Biosynthetically prepared 25-hydroxy-24-epi-brassinolide, reapplied to the cell cultures, is exclusively glucosylated at the 25- hydroxyl group, strongly suggesting regiospecificity of the corresponding glucosyltransferase.

References

[1] N. SONDHI. Isolation of 24-epibrassinolide from leaves of Aegle marmelos and evaluation of its antigenotoxicity employing Allium cepa chromosomal aberration assay[J]. Plant Growth Regulation, 2008, 15 1: 217-224. DOI: 10.1007/s10725-007-9242-7
[2] PINAR OBAKAN. SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells.[J]. PLoS ONE, 2015: e0135788. DOI: 10.1371/journal.pone.0135788
[3] JULIE CARANGE. 24-Epibrassinolide, a Phytosterol from the Brassinosteroid Family, Protects Dopaminergic Cells against MPP-Induced Oxidative Stress and Apoptosis.[J]. Journal of Toxicology, 2011, 2011: 392859. DOI: 10.1155/2011/392859

Epibrassinolide Preparation Products And Raw materials

Raw materials

Preparation Products

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Epibrassinolide Suppliers

Canada 1 China 326 Europe 2 Germany 1 India 1 Japan 2 Slovakia 1 Switzerland 1 United Kingdom 6 United States 29 Global 370

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
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Shandong Yongxin Biotechnology Co., Ltd

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Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.

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J & K SCIENTIFIC LTD.

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Hangzhou Yuhao Chemical Technology Co., Ltd

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View Lastest Price from Epibrassinolide manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Epibrassinolide 78821-43-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-22

BINBO BIOLOGICAL CO.,LTD

Product: Epibrassinolide；24-Epibrassinolide (Brassinolide) 78821-43-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 90%
Supply Ability: 1000 kg
Release date: 2024-11-08

Apeloa production Co.,Limited

Product: Epibrassinolide 78821-43-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20000
Release date: 2024-06-07

78821-43-9, EpibrassinolideRelated Search:

22(S),23(S)-Homobrassinolide 6-Benzylaminopurine Propiconazole Paraquat Uniconazole Chlormequat chloride Prometryn Trifluralin Diethatylethyl Paclobutrazol 22(S),23(S)-HOMOBRASSINOLIDE Homobrassinolide Epibrassinolide TRIS-EPIBRASSINOLIDE 98% (HPLC) 5α-Cholestane Epibrassinolide S,22S,23S-EPIBRASSINOLIDE Epibrassinolide 24-Epibrassinolide/R-epibrassinolide/brassinolide

22R,23R,24R-2ALPHA,3ALPHA,22,28-TETRAHYDROXY-B-HOMO-7-OXA-5ALPHA-ERGOSTA-6-ONE

(22R,23R,24R)-2-ALPHA,3-ALPHA,22,23-TETRAHYDROXY-24-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE

22R,23R,24R-2A,3A,22,23-TETRAHYDROXY-B-HOMO-7-OXA-5A-ERGOSTAN-6-ONE

24R-BRASSINOLIDE

CS-1258

24-EPIBRASSINOLIDE;B1105;BP55

B1105

BP55

24-Epibrassinolide (Brassinolide)

2,4-Epibrassinolide (Brassinosteriod)

24-EPIBRASSINOLIDE

2-ALPHA,3-ALPHA,22R,23R,-TETRAHYDROXY-B-HOMO-7-OXA-5-ALPHA-ERGOSTAN-6-ONE

2-ALPHA,3-ALPHA,22R,23R-TETRADHYDROXY-24R-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE

5-ALPHA-CHOLESTANE-B-HOMO-7-OXA-24-BETA-METHYL-2-ALPHA, 3-ALPHA, 22-ALPHA, 23-ALPHA-TETROL-6-ONE

EPIBRASSINOLIDE 98% (HPLC)

22R,23R,24R-2α,3α,22,23-Tetrahydroxy-B-homo-7-oxa-5α-ergostan-6-one

(22R,23R)-2α,3α,22,23-Tetrahydroxy-7-oxa-B-homo-5α-ergostan-6-one

(22R,23R,24R)-2α,3α,22,23-Tetrahydroxy-24-methyl-6,7-seco-6,7-epoxy-6-oxo-5α-cholestane

(24R)-24-Epibrassinolide

EPIBRASSINOLIDE (EBI)

Epibrassinolide,22R,23R,24R-2α,3α,22,23-Tetrahydroxy-B-homo-7-oxa-5α-ergostan-6-one

Epibrassinolide

(22R/S,23R/S,24R)-2alpha,3alpha,22,23-Tetrahydroxy-beta-home-7-oxa-5-alpha-ergostan-6-one

(1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-1-[(1S,2R,3R,4R)-2,3-Dihydroxy-1,4,5-triMethylhexyl]hexadecahydro-8,9-dihydroxy-10a,12a-diMethyl-6H-benz[c]indeno[5,4-e]oxepin-6-one

Epibrassinolide(24-Epibrassinolide)

4-Epicastasterone

6H-Benz[c]indeno[5,4-e]oxepin-6-one,1-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-triMethylhexyl]hexadecahydro-8,9-dihydroxy-10a,12a-diMethyl-,(1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-

EPIBRASSINOLIDE, >=85%

Brassinolide,BR

5α-CHOLESTANE-B-HOMO-7-OXA-24β-METHYL-2α, 3α, 22α, 23α-TETROL-6-ONE

24-Epicastasterone CAS

(3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-((2S,3R,4R,5R)-3,4-Dihydroxy-5,6-dimethylheptan-2-yl)-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one

(22R,23R,24R)-2α,3α,22,23-Tetrahydroxy-24-Methyl-B-Homo-7-Oxa-5α-Cholestan-6-One

Epibrassinolide, 10 mM in DMSO

Epibrassinolide

2,4-Epibrassinolide Solution, 1mg/mL

24-Epibrutinolideneoside

78821-43-9

Csub2subsub8subHsub4subsub8subOsub6sub

Steriod

Bio-Pesticide

Steroids & Hormones - 13C & 2H

PLANT GROWTH REGULATOR

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids