Biological Metabolism
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Androstenedione

Biological Metabolism
Product Name
Androstenedione
CAS No.
63-05-8
Chemical Name
Androstenedione
Synonyms
4-AD;4-ANDROSTENEDIONE;4-ANDROSTENE-3,17-DIONE;ANDROSTENDIONE;ANDROSTA-4-ENE-3,17-DIONE;Androstenedione (CRM);skf2170;ANDROTEX;SKF 2170;Fecundin
CBNumber
CB8365581
Molecular Formula
C19H26O2
Formula Weight
286.41
MOL File
63-05-8.mol
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Androstenedione Property

Melting point:
170-171 °C(lit.)
Boiling point:
368.77°C (rough estimate)
alpha 
D30 +199° (in chloroform)
Density 
1.0655 (rough estimate)
refractive index 
1.4709 (estimate)
Flash point:
2℃
storage temp. 
Controlled Substance, -20°C Freezer
solubility 
Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Sparingly)
form 
Solid
color 
Dimorphous: Needles from acetone, or crystalsfrom hexane
Water Solubility 
57.28mg/L(25 ºC)
Merck 
13,643
InChIKey
AEMFNILZOJDQLW-QAGGRKNESA-N
CAS DataBase Reference
63-05-8(CAS DataBase Reference)
NIST Chemistry Reference
Androst-4-ene-3,17-dione(63-05-8)
EPA Substance Registry System
4-Androstenedione (63-05-8)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
40-64-52-22-61-60-36-20/21/22-11
Safety Statements 
22-24/25-36-45-36/37-53-26-16
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
BV8150000
HS Code 
29372900
Hazardous Substances Data
63-05-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89562
Product name
Androstenedione
Purity
phyproof? Reference Substance
Packaging
100MG
Price
$262
Updated
2024/03/01
Sigma-Aldrich
Product number
A-075
Product name
Androstenedione solution
Purity
1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$51.4
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2364
Product name
4-Androstenedione
Purity
≥98% (HPLC)
Packaging
250MG
Price
$57
Updated
2023/06/20
Sigma-Aldrich
Product number
SML2364
Product name
4-Androstenedione
Purity
≥98% (HPLC)
Packaging
500MG
Price
$115
Updated
2023/06/20
Cayman Chemical
Product number
9001311
Product name
Androstenedione
Purity
≥98%
Packaging
1mg
Price
$38
Updated
2024/03/01
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Androstenedione Chemical Properties,Usage,Production

Biological Metabolism

The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.

Description

Androstenedione (CRM) (Item No. ISO60161) is a certified reference material categorized as an anabolic androgenic steroid. Androstenedione is a precursor of testosterone (Item Nos. ISO60154 | ISO00154 | 15645) and estrone . Androstenedione is regulated as a Schedule III compound in the United States. Androstenedione (CRM) (Item No. ISO60161) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White to Off-White Solid

Uses

Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)

Definition

ChEBI: A 3-oxo Delta4-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.

Safety Profile

An experimental teratogen. Otherexperimental reproductive effects. Questionablecarcinogen with experimental tumorigenic data. Whenheated to decomposition it emits acrid smoke andirritating fumes.

Purification Methods

Crystallise the dione from hexane. It is soluble in *C6H6, CHCl3 and EtOH. It has max at 239nm. It is a precursor of estrone or testosterone and has androgenic activity. [Ruzicka & Wettstein Helv Chim Acta 18 980 1935, Beilstein 7 III 3636, 7 IV 2381.]

Androstenedione Preparation Products And Raw materials

Raw materials

Preparation Products

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Androstenedione Suppliers

Hubei Changxinsheng Pharm Co.,Ltd
Tel
18971238634
Email
2189484023@qq.com
Country
China
ProdList
500
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
400-880-2824 18107960669
Fax
18140514863
Email
bd@ruiweier.cn
Country
China
ProdList
995
Advantage
58
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Wuhan Wei Shunda Technology Development Co., Ltd.
Tel
86-027-88774375
Fax
86-027-88416321
Email
mwmwhot@163.com
Country
China
ProdList
233
Advantage
65
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17839
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18736
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5658
Advantage
65
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View Lastest Price from Androstenedione manufacturers

Wuhan Xinhao Biotechnology Co., Ltd
Product
Androst-4-ene-3,17-dione 63-05-8
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2024-01-17
hebei hongtan Biotechnology Co., Ltd
Product
4-androstenedione 63-05-8
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000
Release date
2024-03-21
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Androstenedione 63-05-8
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2020-09-08

63-05-8, AndrostenedioneRelated Search:


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  • (8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-quinone
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  • Testosterone Impurity 1(Testosterone EP Impurity A)
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