ChemicalBook > CAS DataBase List > 9-AMINO-6-CHLORO-2-METHOXYACRIDINE

9-AMINO-6-CHLORO-2-METHOXYACRIDINE

Product Name
9-AMINO-6-CHLORO-2-METHOXYACRIDINE
CAS No.
3548-09-2
Chemical Name
9-AMINO-6-CHLORO-2-METHOXYACRIDINE
Synonyms
ACMA;G 185;Nsc 15300;6-chloro-2-methoxy-9-acridinamin;6-chloro-2-methoxy-9-acridinamine;6-chloro-2-methoxyacridin-9-amine;9-AMINO-6-CHLORO-2-METHOXYACRIDINE;9-amino-6-chloro-2-methoxy-acridin;9-amino-3-chloro-7-methoxy-acridin;3-Chloro-7-methoxy-9-aminoacridine
CBNumber
CB8367297
Molecular Formula
C14H11ClN2O
Formula Weight
258.7
MOL File
3548-09-2.mol
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9-AMINO-6-CHLORO-2-METHOXYACRIDINE Property

Melting point:
>250°C
Boiling point:
475.1±35.0 °C(Predicted)
Density 
1.367±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Solubility Insoluble in water; soluble in N, N-dimethylformamide, dimethyl sulfoxide
form 
Solid
pka
8.6(at 25℃)
color 
Yellow
PH Range
Weak blue B uorescence (7.5) to strong blue B uorescence (9.8)
Appearance
Solid Powder
λmax
412nm
Biological Applications
Antimalarial; bactericidal; detection of cancer cells,nucleic acids; treating malformed proteins causing neurodegenerative disease
Major Application
Sensors, detection method for DNA amplification, inhibition of neurode-generative diseases, RNA hydrolysis, fluorescent probes, primers for nucleic acid sequencing, synthesis of nucleic acids, antimalerial agent
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-40
Safety Statements 
22-26-36
WGK Germany 
3
RTECS 
AR7330000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML4162
Product name
ACMA, Fluorescent Dye
Purity
≥95% (HPLC)
Packaging
1 unit
Price
$89
Updated
2025/07/31
Cayman Chemical
Product number
22439
Product name
9-Amino-6-chloro-2-methoxyacridine
Purity
≥98%
Packaging
5mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
22439
Product name
9-Amino-6-chloro-2-methoxyacridine
Purity
≥98%
Packaging
10mg
Price
$122
Updated
2024/03/01
Cayman Chemical
Product number
22439
Product name
9-Amino-6-chloro-2-methoxyacridine
Purity
≥98%
Packaging
25mg
Price
$253
Updated
2024/03/01
AK Scientific
Product number
0974BA
Product name
9-Amino-6-chloro-2-methoxyacridine
Packaging
5mg
Price
$175
Updated
2021/12/16
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9-AMINO-6-CHLORO-2-METHOXYACRIDINE Chemical Properties,Usage,Production

Description

9-Amino-6-chloro-2-methoxyacridine (ACMA) is a cell-permeable fluorescent probe for labeling DNA with selectivity for poly(dA-dT) sequences. ACMA fluorescence is quenched when a pH gradient is established, a property that has been utilized in animal- and plant-based studies. It also inhibits acetylcholinesterase with a Ki value of 49 nM.

Uses

9-Amino-6-chloro-2-methoxyacridine is a nucleic acid stain.

Excitation / Emission Maximum

411 nm/475 nm

9-AMINO-6-CHLORO-2-METHOXYACRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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9-AMINO-6-CHLORO-2-METHOXYACRIDINE Suppliers

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3548-09-2, 9-AMINO-6-CHLORO-2-METHOXYACRIDINERelated Search:


  • 5-amino-2-chloro-7-methoxyacridine
  • 2-Methoxy-6-chloro-9-aminoacridine
  • 2-Methoxy-6-chloroacridine-9-amine
  • 3-Chloro-7-methoxy-9-aminoacridine
  • 6-chloro-2-methoxy-9-acridinamin
  • 6-chloro-2-methoxy-9-acridinamine
  • 9-amino-3-chloro-7-methoxy-acridin
  • 9-amino-6-chloro-2-methoxy-acridin
  • 9-AMINO-6-CHLORO-2-METHOXYACRIDINE
  • ACMA
  • (6-chloro-2-methoxy-acridin-9-yl)amine
  • 6-chloro-2-methoxy-acridin-9-amine
  • 6-chloro-2-methoxyacridin-9-amine
  • Acridine, 9-amino-6-chloro-2-methoxy-
  • 6-chloro-9-amino-2-methoxyacridine
  • 9-amino-3-chloro-7-methoxyacridine
  • G 185
  • Nsc 15300
  • 9-Acridinamine, 6-chloro-2-methoxy-
  • 3548-09-2
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Labels
  • Other Fluorescent Labels
  • BioChemical
  • Biochemicals and Reagents
  • API intermediates
  • Fluorescent
  • Acridine