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9-AMINO-6-CHLORO-2-METHOXYACRIDINE

Product Name
9-AMINO-6-CHLORO-2-METHOXYACRIDINE
CAS No.
3548-09-2
Chemical Name
9-AMINO-6-CHLORO-2-METHOXYACRIDINE
Synonyms
ACMA;G 185;Nsc 15300;6-chloro-2-methoxy-9-acridinamin;6-chloro-2-methoxy-9-acridinamine;6-chloro-2-methoxyacridin-9-amine;9-AMINO-6-CHLORO-2-METHOXYACRIDINE;9-amino-6-chloro-2-methoxy-acridin;9-amino-3-chloro-7-methoxy-acridin;3-Chloro-7-methoxy-9-aminoacridine
CBNumber
CB8367297
Molecular Formula
C14H11ClN2O
Formula Weight
258.7
MOL File
3548-09-2.mol
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9-AMINO-6-CHLORO-2-METHOXYACRIDINE Property

Melting point:
>250°C
Boiling point:
475.1±35.0 °C(Predicted)
Density 
1.367±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Solubility Insoluble in water; soluble in N, N-dimethylformamide, dimethyl sulfoxide
form 
Solid
pka
8.6(at 25℃)
color 
Yellow
PH Range
Weak blue B uorescence (7.5) to strong blue B uorescence (9.8)
Appearance
Solid Powder
λmax
412nm
Biological Applications
Antimalarial; bactericidal; detection of cancer cells,nucleic acids; treating malformed proteins causing neurodegenerative disease
Major Application
Sensors, detection method for DNA amplification, inhibition of neurode-generative diseases, RNA hydrolysis, fluorescent probes, primers for nucleic acid sequencing, synthesis of nucleic acids, antimalerial agent
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-40
Safety Statements 
22-26-36
WGK Germany 
3
RTECS 
AR7330000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML4162
Product name
ACMA, Fluorescent Dye
Purity
≥95% (HPLC)
Packaging
1 unit
Price
$89
Updated
2025/07/31
Cayman Chemical
Product number
22439
Product name
9-Amino-6-chloro-2-methoxyacridine
Purity
≥98%
Packaging
5mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
22439
Product name
9-Amino-6-chloro-2-methoxyacridine
Purity
≥98%
Packaging
10mg
Price
$122
Updated
2024/03/01
Cayman Chemical
Product number
22439
Product name
9-Amino-6-chloro-2-methoxyacridine
Purity
≥98%
Packaging
25mg
Price
$253
Updated
2024/03/01
AK Scientific
Product number
0974BA
Product name
9-Amino-6-chloro-2-methoxyacridine
Packaging
5mg
Price
$175
Updated
2021/12/16
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9-AMINO-6-CHLORO-2-METHOXYACRIDINE Chemical Properties,Usage,Production

Description

9-Amino-6-chloro-2-methoxyacridine (ACMA) is a cell-permeable fluorescent probe for labeling DNA with selectivity for poly(dA-dT) sequences. ACMA fluorescence is quenched when a pH gradient is established, a property that has been utilized in animal- and plant-based studies. It also inhibits acetylcholinesterase with a Ki value of 49 nM.

Uses

9-Amino-6-chloro-2-methoxyacridine is a nucleic acid stain.

Excitation / Emission Maximum

411 nm/475 nm

9-AMINO-6-CHLORO-2-METHOXYACRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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9-AMINO-6-CHLORO-2-METHOXYACRIDINE Suppliers

China 35 Germany 2 Switzerland 1 United States 5 Global 43
Synchem OHG
Tel
+49 5662 408730
Fax
+49 5662 4087320
Email
info@synchem.de
Country
Germany
ProdList
4705
Advantage
70
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

3548-09-2, 9-AMINO-6-CHLORO-2-METHOXYACRIDINERelated Search:

9-AMINOACRIDINE Mepacrine hydrochloride 9-AMINO-6-CHLORO-2-METHOXYACRIDINE 9-[4-(BIS(2-CHLOROETHYL)AMINO)-1-METHYLBUTYL-AMINO]-6-CHLORO-2-METHOXYACRIDINE DIHYDROCHLORIDE N'-(6-CHLORO-2-METHOXY-9-ACRIDINYL)-N-[3-[(6-CHLORO-2-METHOXY-9-ACRIDINYL)AMINO]PROPYL]-N-[(3-METHOXYPHENYL)METHYL]-1,3-PROPANEDIAMINE 6-CHLORO-9-[3-(2-CHLOROETHYLAMINO)PROPYLAMINO]-2-METHOXYACRIDINE DIHYDROCHLORIDE 6-CHLORO-9-[3-N-(2-CHLOROETHYL)ETHYLAMINO]PROPYLAMINO-2-METHOXYACRIDINE DIHYDROCHLORIDE MONODESETHYL QUINACRINE, DIHYDROCHLORIDE 9-AMINO-6-CHLORO-2-METHOXYACRIDINE (ACMA) ACMA (9-Amino-6-chloro-2-methoxyacridine) AURORA KA-4300 AURORA KA-4298 acridine half-mustard ICR 191-OH LABOTEST-BB LT00452833 ACRIDINE HOMODIMER ICR 170-OH BICAPPA

  • 5-amino-2-chloro-7-methoxyacridine
  • 2-Methoxy-6-chloro-9-aminoacridine
  • 2-Methoxy-6-chloroacridine-9-amine
  • 3-Chloro-7-methoxy-9-aminoacridine
  • 6-chloro-2-methoxy-9-acridinamin
  • 6-chloro-2-methoxy-9-acridinamine
  • 9-amino-3-chloro-7-methoxy-acridin
  • 9-amino-6-chloro-2-methoxy-acridin
  • 9-AMINO-6-CHLORO-2-METHOXYACRIDINE
  • ACMA
  • (6-chloro-2-methoxy-acridin-9-yl)amine
  • 6-chloro-2-methoxy-acridin-9-amine
  • 6-chloro-2-methoxyacridin-9-amine
  • Acridine, 9-amino-6-chloro-2-methoxy-
  • 6-chloro-9-amino-2-methoxyacridine
  • 9-amino-3-chloro-7-methoxyacridine
  • G 185
  • Nsc 15300
  • 9-Acridinamine, 6-chloro-2-methoxy-
  • 3548-09-2
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Labels
  • Other Fluorescent Labels
  • BioChemical
  • Biochemicals and Reagents
  • API intermediates
  • Fluorescent
  • Acridine