ChemicalBook > CAS DataBase List > 5-(4-PHENOXYBUTOXY)PSORALEN

5-(4-PHENOXYBUTOXY)PSORALEN

Product Name
5-(4-PHENOXYBUTOXY)PSORALEN
CAS No.
870653-45-5
Chemical Name
5-(4-PHENOXYBUTOXY)PSORALEN
Synonyms
PAP-1;SPS-4251;7H-Furo[3;4-(4-phenoxybutoxy)-;PAP-1, 10 mM in DMSO;2-g][1]benzopyran-7-one;5-(4-PHENOXYBUTOXY)PSORALEN;5-(4-PHENOXYBUTOXY)PSORALEN;PAP1;PAP-1,5-(4-Phenoxybutoxy)psoralen;4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one
CBNumber
CB8370170
Molecular Formula
C21H18O5
Formula Weight
350.36
MOL File
870653-45-5.mol
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5-(4-PHENOXYBUTOXY)PSORALEN Property

Boiling point:
555.8±50.0 °C(Predicted)
Density 
1.269
storage temp. 
2-8°C
solubility 
DMSO: 9 mg/mL
form 
solid
color 
white
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Safety

Risk Statements 
42/43
Safety Statements 
22-36/37-45
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P6124
Product name
5-(4-Phenoxybutoxy)psoralen
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$247
Updated
2024/03/01
Sigma-Aldrich
Product number
P6124
Product name
5-(4-Phenoxybutoxy)psoralen
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$584.4
Updated
2024/03/01
ChemScene
Product number
CS-0299
Product name
PAP-1
Purity
99.69%
Packaging
50mg
Price
$588
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611724
Product name
PAP-1
Packaging
10mg
Price
$306
Updated
2021/12/16
ChemScene
Product number
CS-0299
Product name
PAP-1
Purity
99.69%
Packaging
5mg
Price
$96
Updated
2021/12/16
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5-(4-PHENOXYBUTOXY)PSORALEN Chemical Properties,Usage,Production

Uses

5-(4-Phenoxybutoxy)psoralen (CAS# 870653-45-5) is a selective small molecule blocker of the lymphocyte K+ channel Kv1.3 and is used for the suppression of effector memory T cells in autoimmune diseases.

Biochem/physiol Actions

Selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels.

5-(4-PHENOXYBUTOXY)PSORALEN Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4-PHENOXYBUTOXY)PSORALEN Suppliers

China 86 India 1 Switzerland 1 United States 13 Global 101
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 5-(4-PHENOXYBUTOXY)PSORALEN manufacturers

Career Henan Chemical Co
Product
PAP-1 870653-45-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1ton
Release date
2020-01-10

870653-45-5, 5-(4-PHENOXYBUTOXY)PSORALENRelated Search:

Psoralen 5-(4-PHENOXYBUTOXY)PSORALEN

  • 5-(4-PHENOXYBUTOXY)PSORALEN
  • PAP-1
  • 7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)-
  • 4-(4-Phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one
  • 2-g][1]benzopyran-7-one
  • 4-(4-phenoxybutoxy)-
  • 7H-Furo[3
  • PAP-1,5-(4-Phenoxybutoxy)psoralen
  • 4-(4-Phenoxybutoxy)-7H-furo[3,2-g]chroMen-7-one
  • 4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one
  • 5-(4-PHENOXYBUTOXY)PSORALEN;PAP1
  • SPS-4251
  • KcsA,Potassium Channel,inhibit,PAP1,PAP 1,Inhibitor,PAP-1
  • PAP-1, 10 mM in DMSO
  • 870653-45-5
  • Potassium Channel Modulators
  • Voltage-gated Ion Channels
  • Monovalent Ion Channels
  • Ion Channels
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • API intermediates