ECHINOCYSTIC ACID

Product Name: ECHINOCYSTIC ACID
CAS No.: 510-30-5
Chemical Name: ECHINOCYSTIC ACID
Synonyms: (3B2;16B1;(3u0003B2;16u0003B1;Echinocystic;Albizziagenin;Echicystic acid;ECHINOCYSTIC ACID;Echinocystic acid-RM;ECHINOCYSTIC ACID(SH)
CBNumber: CB8379128
Molecular Formula: C30H48O4
Formula Weight: 472.7
MOL File: 510-30-5.mol

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ECHINOCYSTIC ACID Property

Melting point:: 299-300°C
Boiling point:: 585.0±50.0 °C(Predicted)
Density: 1.14
storage temp.: 2-8°C
solubility: DMF:30.0(Max Conc. mg/mL);63.46(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.7(Max Conc. mM)
form: powder
pka: 4.43±0.70(Predicted)
color: White
LogP: 7.580 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00505
Product name: Echinocystic acid
Purity: ≥95%
Packaging: 5MG
Price: $91.6
Updated: 2022/05/15

Cayman Chemical

Product number: 27476
Product name: Echinocystic Acid
Packaging: 10mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 27476
Product name: Echinocystic Acid
Packaging: 100mg
Price: $879
Updated: 2024/03/01

Cayman Chemical

Product number: 27476
Product name: Echinocystic Acid
Packaging: 50mg
Price: $467
Updated: 2024/03/01

Cayman Chemical

Product number: 27476
Product name: Echinocystic Acid
Packaging: 250mg
Price: $1933
Updated: 2024/03/01

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ECHINOCYSTIC ACID Chemical Properties,Usage,Production

Description

Echinocystic acid is a triterpene that has been found in G. sinensis and has diverse biological activities. It induces nuclear translocation of the glucocorticoid receptor (GR) and reduces TNF-α-induced NF-κB signaling in HEK293 cells overexpressing GFP-GR. Echinocystic acid (12.5, 25, and 50 μM) suppresses RANKL-induced NF-κB activation, ERK phosphorylation, and osteoclastogenesis in mouse bone marrow macrophages (BMMs). It induces neurite outgrowth in Neuro2A cells in a concentration-dependent manner, an effect that can be blocked by the JNK inhibitor SP 600125 . In vivo, echinocystic acid (10 mg/kg per day) decreases escape latency in the Morris water maze and increases the length of neurite processes in the hippocampus of aged mice. Topical administration of echinocystic acid reduces expression of COX-2, inducible nitric oxide synthase (iNOS), TNF-α, and IL-1β and ear edema induced by phorbol 12-myristate 13-acetate (TPA; ) in a mouse model of dermatitis. Echinocystic acid also recovers reductions in femoral bone mineral density and trabecular thickness and number in a rat model of ovariectomy-induced osteoporosis.

Uses

Echinocystic Acid is a potential entry inhibitor for the HCV infection.

Definition

ChEBI: Echinocystic acid is a triterpenoid.

ECHINOCYSTIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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ECHINOCYSTIC ACID Suppliers

China 170 Germany 2 India 2 United Kingdom 6 United States 22 Global 202

Carbosynth

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Apin Chemicals Limited (UK)

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Leancare Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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UK GREEN SCIENTIFIC CO.,LIMITED

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Apin Chemicals Ltd.

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View Lastest Price from ECHINOCYSTIC ACID manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Echinocystic Acid 510-30-5
Price: US $200.00-85.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-23

Hebei Weibang Biotechnology Co., Ltd

Product: ECHINOCYSTIC ACID 510-30-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

Hebei Shengyang Water Conservancy Engineering Co., Ltd.

Product: Echinocystic Acid 510-30-5
Price: US $18.00/kg
Min. Order: 1kg
Purity: 99.9
Supply Ability: 5000
Release date: 2024-05-11

510-30-5, ECHINOCYSTIC ACIDRelated Search:

4-TERT-BUTYLCYCLOHEXANECARBOXYLIC ACID 2-BUTYL-2-ETHYL-1,3-PROPANEDIOL ECHINOCYSTIC ACID 3-Methyl-1-butanol 2-Propylpentanoic acid TRANS-9-OCTADECENOL ECHINOCYSTIC ACID-3-GLUCOSIDE,ECHINOCYSTIC ACID-3-O-GLUCOSIDE,ECHINOCYSTIC ACID-3-O-GLUCOSIDE WITH HPLC CIS-9-HENEICOSENE CAULOPHYLLOGENIN 4-BUTYLCYCLOHEXANE CARBOXYLIC ACID 2-Methyl-2-propyl-1,3-propanediol 2-HYDROXYCYCLOHEXANECARBOXYLIC ACID PENTASACCHARIDE OF ECHINOCYSTIC ACID 2-ETHYLNONANOIC ACID 2-(1,1-dimethylethyl)-4-methylcyclohexan-1-ol MYRISTELAIDIC ACID 3-HYDROXYHEXADECANOIC ACID 6,6-DIMETHYLHEPTANOIC ACID

ECHINOCYSTIC ACID

3-B,16-A-DIHYDROXYOLEAN-12-EN-28-OIC ACID

3BETA,16ALPHA-DIHYDROXY-OLEAN-12-EN-28-OIC ACID

(3beta,16alpha)-3,16-dihydroxyolean-12-en-28-oic acid

Echinocystic

ECHINOCYSTIC ACID(SH)

ECHINOCYSTIC ACID hplc

Echinocystic acid 510-30-5

(4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,10-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid

ECHINOCYSTIC ACID WITH HPLC

3β,16α-Dihydroxy-5α-oleana-12-ene-28-oic acid

3β,16α-Dihydroxyolean-12-en-28-oic acid

Echicystic acid

Albizziagenin

Echinocystic acid, 98%, from Hedera Linn.

ECHINOCYSTIC ACID USP/EP/BP

(3B2

(3u0003B2

)-3,16-dihydroxyolean-12-en-28-oic acid

16B1

16u0003B1

Echinocystic acid (6CI)

Olean-12-en-28-oic acid, 3,16-dihydroxy-, (3β,16α)-

Echinocystic acid in methanol

Echinocystic acid-RM

510-30-5

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Tri-Terpenoids

Inhibitors