4-FLUOROPHENYL METHYL SULFONE

Product Name: 4-FLUOROPHENYL METHYL SULFONE
CAS No.: 455-15-2
Chemical Name: 4-FLUOROPHENYL METHYL SULFONE
Synonyms: 4-Fluorophenyl;4-FLUOROPHENYL METHY;Formula: FC6H4SO2CH3;Bicalutamide Impurity 30;4-FLUOROPHENYL METHYL SULFONE;Methyl 4-fluorophenyl sulfone;4-FLUOROPHENYL METHYL SULPHONE;Sulfone, p-fluorophenyl methyl;Methyl(4-fluorophenyl) sulfone;p-Fluorophenyl(methyl) sulfone
CBNumber: CB8395595
Molecular Formula: C7H7FO2S
Formula Weight: 174.19
MOL File: 455-15-2.mol

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4-FLUOROPHENYL METHYL SULFONE Property

Melting point:: 78-81 °C (lit.)
Boiling point:: 95-97°C 7mm
Density: 1.2768 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Dichloromethane, Dimethyl Sulfoxide, Methanol
form: Adhering Crystalline Powder
color: Almost white
BRN: 2045674
InChI: InChI=1S/C7H7FO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,1H3
InChIKey: DPJHZJGAGIWXTD-UHFFFAOYSA-N
SMILES: C1(F)=CC=C(S(C)(=O)=O)C=C1
CAS DataBase Reference: 455-15-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22
Safety Statements: 24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29309090
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 184330
Product name: 4-Fluorophenyl methyl sulfone
Purity: 97%
Packaging: 5g
Price: $44.8
Updated: 2023/06/20

TCI Chemical

Product number: F0651
Product name: 4-Fluorophenyl Methyl Sulfone
Purity: >98.0%(GC)
Packaging: 5g
Price: $72
Updated: 2025/07/31

TCI Chemical

Product number: F0651
Product name: 4-Fluorophenyl Methyl Sulfone
Purity: >98.0%(GC)
Packaging: 25g
Price: $284
Updated: 2025/07/31

Frontier Specialty Chemicals

Product number: JK485417
Product name: 4-Fluorophenyl Methyl Sulfone
Purity: 98%
Packaging: 25g
Price: $309
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 10335
Product name: 4-Fluorophenyl Methyl Sulfone
Packaging: 0.5g
Price: $2000
Updated: 2021/12/16

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4-FLUOROPHENYL METHYL SULFONE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

4-Fluorophenyl methyl sulfone was used in the preparation of 4-(4′-trifluoromethoxyphenoxy)phenyl methyl sulfone.

Uses

4-Fluorophenyl methyl sulfone is used for preparation of substituted indazole amides as glucokinase activators.

Synthesis

A 500 mL flask was charged with 25.2 g of sodium sulfite, 100 mL of water, and 16.8 g of sodium bicarbonate. Heat to reflux and after all the solids are dissolved, add 21.0 g of 4-fluorobenzenesulfonyl chloride in batches and continue to heat to reflux for 4 hours. Cool to 40 C, 18.9 g of dimethyl sulfate was added dropwise from the dispensing funnel, with a dropwise acceleration to maintain the system temperature at 40~45 is appropriate. After dropping, the reaction was held for 2.5 h. After the methylation reaction was complete, the reaction was heated and refluxed for 1 h. The reaction was then heated and refluxed. Add 200mL of water, static cooling to room temperature, precipitated a large number of solids, filtered, washed with water, that is, p-fluorobenzenesulfone.

4-FLUOROPHENYL METHYL SULFONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-FLUOROPHENYL METHYL SULFONE Suppliers

Americas 1 Belgium 1 Canada 1 China 106 Europe 1 France 1 Germany 2 India 7 Italy 1 Japan 3 Switzerland 3 Ukraine 1 United Kingdom 12 United States 24 Global 164

Nanjing Thander New Material Science & Technology Co., Ltd

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Shanghai Longsheng chemical Co.,Ltd.

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View Lastest Price from 4-FLUOROPHENYL METHYL SULFONE manufacturers

Honest Joy Holdings Limited

Product: 4-Fluorophenyl methyl sulfone 455-15-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.3%
Supply Ability: 100 tons
Release date: 2022-02-21

Career Henan Chemical Co

Product: 4-FLUOROPHENYL METHYL SULFONE 455-15-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 20ton
Release date: 2019-12-20

Nanjing jinheyou Trading Co., Ltd.

Product: 4-FLUOROPHENYL METHYL SULFONE 455-15-2
Price: US $0.00/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 20kg/month
Release date: 2019-11-04

455-15-2, 4-FLUOROPHENYL METHYL SULFONERelated Search:

Ethyl 4-fluorobenzoate 4-FLUOROPHENYL METHYL SULFONE 4-Fluorophenyl sulfone 4-METHYLSULFONYL-2-NITROFLUOROBENZENE (4-FLUOROBENZENESULFONYL)ACETONITRILE BIS(4-FLUORO-3-NITROPHENYL) SULFONE Dimethyl sulfone Methyl phenyl sulfone 2-CHLORO-N-(4-[(4-FLUOROPHENYL)SULFONYL]PHENYL)ACETAMIDE [5-[(4-FLUOROPHENYL)SULFONYL]-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL]METHANOL 2-FLUOROPHENYL METHYL SULFONE 3-Fluorophenyl Methyl Sulfone P-FLUOROPHENYL-P-METHOXYPHENYL SULFONE 1-((2-[(4-CHLOROPHENYL)SULFONYL]ETHYL)SULFONYL)-2,3,4,5,6-PENTAFLUOROBENZENE 2-[(4-FLUOROPHENYL)SULFONYL]-N-(4-METHOXYPHENYL)ACETAMIDE N-(4-[(4-FLUOROPHENYL)SULFONYL]PHENYL)-3-(TRIFLUOROMETHYL)BENZENECARBOXAMIDE [5-[(4-FLUOROPHENYL)SULFONYL]-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL]METHYL 2-CHLOROACETATE 4-FLUOROPHENYL 4-PHENYL-1,2,3-THIADIAZOL-5-YL SULFONE

Sulfone, p-fluorophenyl methyl

4-FLUOROPHENYL METHYL SULPHONE

4-FLUOROPHENYL METHYL SULFONE

4-Fluorobenzenesulfinic Acid Methyl Este

4-Fluorophenyl

4-Fluorophenyl methyl sulphone 98%

4-Fluorophenylmethylsulphone98%

Benzene,1-fluoro-4-(methylsulfonyl)-

4-Fluorobenzenesulfinic Acid Methyl Ester

1-FLUORO-4-(METHYLSULFONYL)BENZENE

1-fluoro-4-(methylsulphonyl)benzene

4-Fluorophenylmethylsulfone,97%

Methyl 4-fluorophenyl sulfone

Methyl(4-fluorophenyl) sulfone

p-Fluorophenyl(methyl) sulfone

4-Fluorophenyl methyl sulfone,99%

1-Fluoro-4-Methanesulfonylbenzene

Sulfone, p-Fluorophenyl Methyl Sulfone

4-Fluorophenyl Methyl sulfone, 98%+

Formula: FC6H4SO2CH3

4-FLUOROPHENYL METHY

4-FluorophenylMethylSulfone&gt

Bicalutamide Impurity 30

4-Fluorophenyl methyl sulfone - [F3456]

455-15-2

FC6H4SO2CH3

Building Blocks

Organic Building Blocks

Sulfur Compounds

Sulfones

Aromatics Compounds

Aromatics

Sulfur & Selenium Compounds

Organic Building Blocks

Sulfones

Sulfur Compounds