4-Fluorophenyl sulfone
- Product Name
- 4-Fluorophenyl sulfone
- CAS No.
- 383-29-9
- Chemical Name
- 4-Fluorophenyl sulfone
- Synonyms
- fone;NSC-87584;JACS-383-29-9;4-Fluorophenyl sulfo;P-FLUOROPHENYL SULFONE;4-FLUOROPHENYL SULFONE;4-FLUOROPHENYL SULPHONE;4-Fluorophenyl sulfone,99%;4,4'-DIFLUOROPHENYL SULFONE;BIS(P-FLUOROPHENYL) SULFONE
- CBNumber
- CB9768439
- Molecular Formula
- C12H8F2O2S
- Formula Weight
- 254.25
- MOL File
- 383-29-9.mol
4-Fluorophenyl sulfone Property
- Melting point:
- 98-100 °C(lit.)
- Boiling point:
- 367.9±27.0 °C(Predicted)
- Density
- 1.3538 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- soluble in Methanol
- form
- Crystals or Powder
- color
- White to brown
- BRN
- 1970911
- InChI
- InChI=1S/C12H8F2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H
- InChIKey
- PLVUIVUKKJTSDM-UHFFFAOYSA-N
- SMILES
- S(C1=CC=C(F)C=C1)(C1=CC=C(F)C=C1)(=O)=O
- CAS DataBase Reference
- 383-29-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Sulfone, bis(4-fluorophenyl)-(383-29-9)
- EPA Substance Registry System
- Benzene, 1,1'-sulfonylbis[4-fluoro- (383-29-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F15145
- Product name
- Bis(4-fluorophenyl) sulfone
- Purity
- 99%
- Packaging
- 25g
- Price
- $191
- Updated
- 2025/07/31
- Product number
- 8.41368
- Product name
- Bis(4-fluorophenyl) sulfone
- Purity
- for synthesis
- Packaging
- 5G
- Price
- $95.4
- Updated
- 2025/07/31
- Product number
- D0537
- Product name
- Bis(4-fluorophenyl) Sulfone
- Purity
- >99.0%(GC)
- Packaging
- 10g
- Price
- $104
- Updated
- 2025/07/31
- Product number
- D0537
- Product name
- Bis(4-fluorophenyl) Sulfone
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $181
- Updated
- 2025/07/31
- Product number
- D0537
- Product name
- Bis(4-fluorophenyl) Sulfone
- Purity
- >99.0%(GC)
- Packaging
- 250g
- Price
- $1001
- Updated
- 2025/07/31
4-Fluorophenyl sulfone Chemical Properties,Usage,Production
Chemical Properties
white to brown crystals or powder
Uses
4-Fluorophenylsulfone was used in substitution reactions with deprotonated amines.
Synthesis
824-80-6
383-29-9
GENERAL PROCEDURE: A mixture of sodium aryl sulfite (1 mmol), copper(II) acetate (0.5 mmol) and acetonitrile (1 mL) was stirred in air at 60°C for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered through filter paper. Subsequently, the organic phase was evaporated under reduced pressure and the residue was purified by fast column chromatography (silica gel, eluent ethyl acetate/petroleum ether=1/10) to afford the target product 4,4'-difluorodiphenyl sulfone. All products were known compounds and their structures were confirmed by 1H NMR, 13C NMR and high resolution mass spectrometry (HRMS).
References
[1] Journal of Chemical Research, 2014, vol. 38, # 5, p. 265 - 268
4-Fluorophenyl sulfone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Fluorophenyl sulfone manufacturers
- Product
- 4,4'-Sulfonylbis(fluorobenzene) 383-29-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2024-11-09
- Product
- 4-Fluorophenyl sulfone 383-29-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-06-25
- Product
- 4-Fluorophenyl sulfone 383-29-9
- Price
- US $308.60-292.80/KG
- Min. Order
- 20KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-08-03