ChemicalBook > CAS DataBase List > ex229 (compound 991)

ex229 (compound 991)

Product Name
ex229 (compound 991)
CAS No.
1219739-36-2
Chemical Name
ex229 (compound 991)
Synonyms
EX229;EX-229;EX 229;EX229;ex229 (compound 991);EX229, 10 mM in DMSO;AMPK Activator 991 (Compound 991);AMP-activated protein kinase,inhibit,EX 229,AMPK,Inhibitor,EX-229,EX229;5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methylbenzoic acid;5-[[6-Chloranyl-5-(1-Methylindol-5-Yl)-1h-Benzimidazol-2-Yl]oxy]-2-Methyl-Benzoic Acid;Benzoic acid, 5-[[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methyl-
CBNumber
CB83960141
Molecular Formula
C24H18ClN3O3
Formula Weight
431.87
MOL File
1219739-36-2.mol
More
Less

ex229 (compound 991) Property

Boiling point:
706.4±70.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.30 mg/ml
form 
A solid
pka
3.40±0.25(Predicted)
color 
Off-white to pink
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-0063368
Product name
EX229
Purity
98.37%
Packaging
5mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-0063368
Product name
EX229
Purity
98.37%
Packaging
10mg
Price
$140
Updated
2021/12/16
ChemScene
Product number
CS-0063368
Product name
EX229
Purity
98.37%
Packaging
25mg
Price
$290
Updated
2021/12/16
ChemScene
Product number
CS-0063368
Product name
EX229
Purity
98.37%
Packaging
50mg
Price
$490
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573154
Product name
EX-229
Purity
>98%
Packaging
100mg
Price
$1060.8
Updated
2021/12/16
More
Less

ex229 (compound 991) Chemical Properties,Usage,Production

Uses

AMPK Activator 991 is a small benzimidazole derivative that potently activates AMP-activated protein kinase (AMPK) to increase glucose transport in skeletal muscle, with possible applications in treating a variety of metabolic disorders, such as Type 2 diabetes.

IC 50

AMPK α1β1γ1: 0.06 μM (Kd); AMPK α2β1γ1: 0.06 μM (Kd); AMPK α1β2γ1: 0.51 μM (Kd)

ex229 (compound 991) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ex229 (compound 991) Suppliers

Ningbo Chaoming Biotechnology Co., Ltd
Tel
13301662590
Email
mandy@atkchemical.com
Country
China
ProdList
9540
Advantage
58
Nanjing Chemlin Chemical Co., Ltd
Tel
13913916777
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15984
Advantage
64
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
sales@uhnshanghai.com
Country
China
ProdList
998
Advantage
58
Wuhan Kaymke Chemical Co., Ltd.,
Tel
027-87342388 18086026008
Fax
027-87342388
Email
sales@kaymke.com
Country
China
ProdList
3584
Advantage
55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4810
Advantage
55
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
981
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71615
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
Advantage
62

1219739-36-2, ex229 (compound 991)Related Search:


  • ex229 (compound 991)
  • EX229
  • EX-229
  • 5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methylbenzoic acid
  • EX 229;EX229
  • Benzoic acid, 5-[[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methyl-
  • 5-[[6-Chloranyl-5-(1-Methylindol-5-Yl)-1h-Benzimidazol-2-Yl]oxy]-2-Methyl-Benzoic Acid
  • AMPK Activator 991 (Compound 991)
  • AMP-activated protein kinase,inhibit,EX 229,AMPK,Inhibitor,EX-229,EX229
  • 5-((6-Chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic acid
  • 5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-1,3-benzodiazol-2-yl]oxy}-2-methylbenzoic acid
  • EX229, 10 mM in DMSO
  • 1219739-36-2
  • API