ChemicalBook > CAS DataBase List > 3,3-BIS(P-HYDROXYPHENYL)OXINDOLE

3,3-BIS(P-HYDROXYPHENYL)OXINDOLE

Product Name
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE
CAS No.
125-13-3
Chemical Name
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE
Synonyms
isolax;lavema;recolon;hoscolax;neodrast;normalax;veripaque;propellax;phenolisatin;OXYPHENISATIN
CBNumber
CB8404338
Molecular Formula
C20H15NO3
Formula Weight
317.34
MOL File
125-13-3.mol
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3,3-BIS(P-HYDROXYPHENYL)OXINDOLE Property

Melting point:
260-261 °C
Boiling point:
562.9±50.0 °C(Predicted)
Density 
1.352±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 28 mg/mL (88.23 mM)
form 
Solid
pka
9.42±0.30(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S675407
Product name
3,3-BIS(4-HYDROXYPHENYL)-OXINDOLE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$216
Updated
2025/07/31
Sigma-Aldrich
Product number
S675407
Product name
3,3-BIS(4-HYDROXYPHENYL)-OXINDOLE
Purity
AldrichCPR
Packaging
1G
Price
$209
Updated
2024/03/01
TRC
Product number
O876965
Product name
Oxyphenisatine
Packaging
25g
Price
$1175
Updated
2021/12/16
Matrix Scientific
Product number
172365
Product name
3,3-Bis(p-hydroxyphenyl)oxindole
Packaging
1g
Price
$172
Updated
2021/12/16
AK Scientific
Product number
1424BA
Product name
Oxyphenisatine
Packaging
1g
Price
$282
Updated
2021/12/16
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3,3-BIS(P-HYDROXYPHENYL)OXINDOLE Chemical Properties,Usage,Production

Chemical Properties

Crystallization. Melting point>260℃.

Uses

Oxyphenisatine is a diphenolic laxative and it’s prodrug Oxyphenisatine acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468 by inducing multifaceted cell starvation response, which ultimately induces programmed cell death.

Definition

ChEBI: Oxyphenisatine is a member of indoles.

in vivo

Toxicity studies demonstrate that mice tolerate IP administration of OXY at 300 mg/kg once daily or 200 mg/kg twice daily. Administration of OXY at 300 mg/kg IP once daily for 10 days results in significantly smaller tumors from day 33 to day 52[1].

3,3-BIS(P-HYDROXYPHENYL)OXINDOLE Preparation Products And Raw materials

Raw materials

Isatin

Preparation Products

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3,3-BIS(P-HYDROXYPHENYL)OXINDOLE Suppliers

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View Lastest Price from 3,3-BIS(P-HYDROXYPHENYL)OXINDOLE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE 125-13-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-11-10
Career Henan Chemica Co
Product
3,3-BIS(P-HYDROXYPHENYL)OXINDOLE 125-13-3
Price
US $8.00/KG
Min. Order
1g
Purity
Min98% HPLC/GC
Supply Ability
g/kg/ton
Release date
2020-11-02

125-13-3, 3,3-BIS(P-HYDROXYPHENYL)OXINDOLERelated Search:

Uracil Dihydrocaffeic acid 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid Diphenylmethane Oxindole 3,3-BIS-(3,5-DIMETHYL-4-HYDROXYPHENYL)-1,3-DIHYDRO-INDOL-2-ONE Sulisatine oxyphenisatine di(acetate) 3,3-Bis(3-methyl-4-hydroxyphenyl)indoline-2-on 3,3-BIS(P-HYDROXYPHENYL)OXINDOLE

  • 3,3-Bis(4-hydroxyphenyl)indoline-2-one
  • 3,3-bis(4-hydroxyphenyl)-1H-indol-2-one
  • 3,3-Bis(4-Hydroxsyphenyl)-2(3H)-Indolone
  • 3,3-Bis(4-hydroxyphenyl)-1,3-dihydro-2H-indol-2-one
  • recolon
  • veripaque
  • 3,3-bis(4-hydroxyphenyl)indolin-2-one
  • 3,3-BIS(4-HYDROXYPHENYL)-2-INDOLINONE
  • 3,3-BIS(4-HYDROXYPHENYL)OXINDOLE
  • 3,3-BIS(4-HYDROXPHENYL)OXINDOLE
  • 3,3-BIS(P-HYDROXYPHENYL)OXINDOLE
  • 4,4’-dihydroxydiphenylisatin
  • diphenolisatin
  • hoscolax
  • isatinbisphenol
  • isolax
  • lavema
  • neodrast
  • normalax
  • oxyphenisatine
  • phenolisatin
  • propellax
  • OXYPHENISATIN
  • TIMTEC-BB SBB008302
  • 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-2h-indol-2-on
  • 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-2h-indol-2-one
  • 3,3-bis(p-hydroxyphenyl)-2-indolinon
  • 3,3-bis(p-hydroxyphenyl)-2-indolinone
  • 2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-
  • 3,3-BIS(P-HYDROXYPHENYL)OXINDOLE USP/EP/BP
  • Compound T7071
  • Oxyphenisatine Impurity
  • Bromhexine Impurity 27
  • Oxyphenisatine, 10 mM in DMSO
  • 3,3-Di(4-hydroxyphenyl)-2(3H)-indolinone
  • 125-13-3
  • C20H15NO3