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Dihydrocaffeic acid

Product Name
Dihydrocaffeic acid
CAS No.
1078-61-1
Chemical Name
Dihydrocaffeic acid
Synonyms
NSC 407275;NSC 624007;Hydrocaffeate;HYDROCAFFEIC ACID;3-propionic acid;DIHYDROCAFFEIC ACID;DIHYDROCAFFEIC ACID(RG);3,4-DIHYDROCAFFEIC ACID;13C6]-Dihydrocaffeic acid;4-Dihydroxyhydrocinnamic acid
CBNumber
CB1439090
Molecular Formula
C9H10O4
Formula Weight
182.17
MOL File
1078-61-1.mol
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Dihydrocaffeic acid Property

Melting point:
136-139 °C(lit.)
Boiling point:
418℃
Density 
1.398
Flash point:
220℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.75±0.10(Predicted)
color 
Pale Beige to Pale Brown
Water Solubility 
Slightly soluble in water.
BRN 
2213449
InChI
InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
InChIKey
DZAUWHJDUNRCTF-UHFFFAOYSA-N
SMILES
C1(CCC(O)=O)=CC=C(O)C(O)=C1
LogP
0.115 (est)
CAS DataBase Reference
1078-61-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
MW5143500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
102601
Product name
3,4-Dihydroxyhydrocinnamic acid
Purity
98%
Packaging
2.5G
Price
$55.56
Updated
2024/03/01
Sigma-Aldrich
Product number
102601
Product name
3,4-Dihydroxyhydrocinnamic acid
Purity
98%
Packaging
10G
Price
$237
Updated
2024/03/01
Sigma-Aldrich
Product number
102601
Product name
3,4-Dihydroxyhydrocinnamic acid
Purity
98%
Packaging
25G
Price
$463
Updated
2024/03/01
Alfa Aesar
Product number
A11638
Product name
3-(3,4-Dihydroxyphenyl)propionic acid, 98+%
Packaging
5g
Price
$60.5
Updated
2024/03/01
Alfa Aesar
Product number
A11638
Product name
3-(3,4-Dihydroxyphenyl)propionic acid, 98+%
Packaging
25g
Price
$186
Updated
2024/03/01
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Dihydrocaffeic acid Chemical Properties,Usage,Production

Description

Dihydrocaffeic acid is a polyphenol that has diverse biological activities, including antioxidant, neuroprotective, and enzyme inhibitory properties. Dihydrocaffeic acid scavenges ABTS (; IC50 = 81.86 μg/ml) and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ; IC50 = 192.86 μg/ml) radicals and increases the survival of RGC-5 mouse retinal ganglion cells under hypoxic conditions and in the presence of S-nitroso-N-acetyl-D,L-penicillamine (SNAP; ) in a concentration-dependent manner. It also decreases endothelial nitric oxide synthase (eNOS) activity in EA.hy926 human endothelial cells in a concentration-dependent manner. In vivo, dihydrocaffeic acid (30 mg/kg) decreases infarct size in a rat model of transient ischemia induced by middle cerebral artery occlusion (MCAO).

Chemical Properties

Brown Solid

Uses

Dihydrocaffeic Acid is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective activity. Dihydrocaffei c Acid is a metabolite of Caffeic Acid (C08000) with potent antioxidant properties.

Uses

3-(3,4-Dihydroxyphenyl)propionic acid it can be used to produce 3-(3,4-dihydroxy-phenyl)-propionic acid octyl ester by heating.

Definition

ChEBI: A monocarboxylic acid that is 3-phenylpropionic acid substituted by hydroxy groups at positions 3 and 4. It is a metabolite of caffeic acid and exhibits antioxidant activity.

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Dihydrocaffeic acid Suppliers

Hangzhou Viablife Biotech Co., Ltd.
Tel
0571-88766806 13386527431
Email
sales@viablife.com
Country
China
ProdList
22
Advantage
58
Henan Evonik Biotechnology Co. LTD
Tel
16650615803
Email
hnyingchuang@163.com
Country
China
ProdList
3982
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Jinxiang Chemical (Danyang) Products Co., Ltd.
Tel
025-86819862 13913839793
Fax
0086-25-86819859
Email
nancyzong@jinchemical.com
Country
China
ProdList
97
Advantage
74
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17839
Advantage
64
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View Lastest Price from Dihydrocaffeic acid manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Dihydrocaffeic acid 1078-61-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-14
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
Product
3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID 1078-61-1
Price
US $25.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
20 tons
Release date
2021-12-31
Hebei Guanlang Biotechnology Co., Ltd.
Product
3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID 1078-61-1
Price
US $10.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-12-03

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