ChemicalBook > CAS DataBase List > (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

Product Name
(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
CAS No.
3916-18-5
Chemical Name
(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
Synonyms
DL-DOPS;DL-THREO-DOPS;(±)-threo-DOPS;DL-threo-Droxidopa;Droxidopa Impurity 4;Droxidopa Impurity 10;Droxidopa DL-threo Impurity;DL-threo-Dihydroxyphenylserine;3-dihydroxy-betthreo-dl-tyrosin;β,3-Dihydroxy-DL-threo-tyrosine
CBNumber
CB3208010
Molecular Formula
C9H11NO5
Formula Weight
213.19
MOL File
3916-18-5.mol
More
Less

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Property

Melting point:
202-205°C (dec.)
Boiling point:
549.8±50.0 °C(Predicted)
Density 
1.608±0.06 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
ethanol: 50 mg/mL Solutions should be freshly prepared.
form 
powder
pka
2.09±0.24(Predicted)
color 
off-white to yellow-tan
More
Less

Safety

WGK Germany 
2
RTECS 
VT9626000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D689950
Product name
DL-threo-Droxidopa
Packaging
25mg
Price
$175
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006488
Product name
BETA-D,L-(3,4-DIHYDROXYPHENYL)-SERINE
Purity
95.00%
Packaging
25MG
Price
$739.2
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006488
Product name
BETA-D,L-(3,4-DIHYDROXYPHENYL)-SERINE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
More
Less

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian.

Definition

ChEBI: Droxidopa is a serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension It has a role as a prodrug, a vasoconstrictor agent and an antihypertensive agent. It is a L-tyrosine derivative and a member of catechols.

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30240
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233717@qq.com
Country
China
ProdList
9919
Advantage
12
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58

3916-18-5, (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACIDRelated Search:


  • H-DL-SER(3,4-DIHYDROXYPHENYL)-OH
  • H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
  • H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SER-OH
  • DL-DOPS
  • DL-THREO-BETA-(3,4-DIHYDROXYPHENYL)SERINE
  • DL-THREO-DOPS
  • D,L-(3,4-DIHYDROXYPHENYL)-SERINE
  • BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
  • THREO-3,4-DIHYDROXY PHENYL SERINE
  • 3-dihydroxy-betthreo-dl-tyrosin
  • 3-dihydroxy-dl-tyrosinethreo-bet
  • 4-dihydroxyphenyl)-3-(dl-threo-serin
  • dl-threo-3-(3,4-dihydroxyphenyl)serine
  • dl-threo-3,4-dihydroxyphenylserine
  • threo-beta,3-dihydroxy-DL-tyrosine
  • Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo.
  • DL-threo-Dihydroxyphenylserine
  • DL-Tyrosine, b,3-dihydroxy-, threo-
  • D-Tyrosine, β,3-dihydroxy-, (βS)-rel-
  • Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo- (8CI)
  • threo-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic acid
  • ((2RS,3RS)-2-Amino-3-(3,4-dihydroxy-phenyl)-3-hydr
  • DL-threo-3,4-Dihydroxyphenylserine, DL-threo-DOPS
  • (±)-threo-DOPS
  • (±)-β,3-Dihydroxy-threo-tyrosine
  • rac-(2S*,3R*)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic acid
  • β,3-Dihydroxy-DL-threo-tyrosine
  • DL-threo-Droxidopa
  • (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
  • (+/-)-THREO-DIHYDROXYPHENYLSERINE (+/-)- THREO-DOPS
  • DL-THREO-B-(3,4-DIHYDROXYPHENYL)SERINE
  • Droxidopa Impurity 4
  • Beta-D,L-(3,4-Dihydroxyphenyl)-Serine
  • Droxidopa Impurity 10 (DL-threo-Droxidopa)
  • Droxidopa Impurity 10
  • (βS)-rel-β,3-Dihydroxy-D-tyrosine
  • (2RS,3RS)-2-AMino-3-(3,4-dihydroxy-phenyl)-3-hydroxy-propionic acid, DL-DOPS, DL-Droxidopa
  • H-DL-b-(3,4-Dihydroxyphenyl)-DL-Ser-OH
  • Droxidopa DL-threo Impurity
  • rel-(2R,3S)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
  • 3-D,L-(3,4-dihydroxy-phenyl-)-serine
  • 3916-18-5
  • 3916-28-5
  • Amines
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals