ChemicalBook > CAS DataBase List > (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID

Product Name
(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
CAS No.
3916-18-5
Chemical Name
(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
Synonyms
DL-DOPS;DL-THREO-DOPS;(±)-threo-DOPS;DL-threo-Droxidopa;Droxidopa Impurity 4;Droxidopa Impurity 10;Droxidopa DL-threo Impurity;DL-threo-Dihydroxyphenylserine;3-dihydroxy-betthreo-dl-tyrosin;β,3-Dihydroxy-DL-threo-tyrosine
CBNumber
CB3208010
Molecular Formula
C9H11NO5
Formula Weight
213.19
MOL File
3916-18-5.mol
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(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Property

Melting point:
202-205°C (dec.)
Boiling point:
549.8±50.0 °C(Predicted)
Density 
1.608±0.06 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
ethanol: 50 mg/mL Solutions should be freshly prepared.
form 
powder
pka
2.09±0.24(Predicted)
color 
off-white to yellow-tan
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Safety

WGK Germany 
2
RTECS 
VT9626000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
D689950
Product name
DL-threo-Droxidopa
Packaging
25mg
Price
$175
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006488
Product name
BETA-D,L-(3,4-DIHYDROXYPHENYL)-SERINE
Purity
95.00%
Packaging
25MG
Price
$739.2
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006488
Product name
BETA-D,L-(3,4-DIHYDROXYPHENYL)-SERINE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
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(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian.

Definition

ChEBI: Droxidopa is a serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension It has a role as a prodrug, a vasoconstrictor agent and an antihypertensive agent. It is a L-tyrosine derivative and a member of catechols.

(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Suppliers

Canada 1 China 22 Germany 1 India 1 Japan 1 Sweden 1 Switzerland 1 United Kingdom 1 United States 9 Global 38
Ramidus AB
Tel
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Fax
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Email
hans.holmberg@synthelec.se
Country
Sweden
ProdList
1103
Advantage
30

3916-18-5, (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACIDRelated Search:

4-Hydroxybenzyl alcohol DOPS DL-Serine DL-Tyrosine (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID BOC-D-THREO-3-(3,4-DIMETHOXYPHENYL)SERINE DROXIDOPA BOC-D-THREO-3-(BENZO[1,3]DIOXOL-5-YL)SERINE 3-(3,4-DIBENZYLOXYPHENYL)-SERINE

  • H-DL-SER(3,4-DIHYDROXYPHENYL)-OH
  • H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
  • H-DL-BETA-(3,4-DIHYDROXYPHENYL)-DL-SER-OH
  • DL-DOPS
  • DL-THREO-BETA-(3,4-DIHYDROXYPHENYL)SERINE
  • DL-THREO-DOPS
  • D,L-(3,4-DIHYDROXYPHENYL)-SERINE
  • BETA-(3,4-DIHYDROXYPHENYL)-DL-SERINE
  • THREO-3,4-DIHYDROXY PHENYL SERINE
  • 3-dihydroxy-betthreo-dl-tyrosin
  • 3-dihydroxy-dl-tyrosinethreo-bet
  • 4-dihydroxyphenyl)-3-(dl-threo-serin
  • dl-threo-3-(3,4-dihydroxyphenyl)serine
  • dl-threo-3,4-dihydroxyphenylserine
  • threo-beta,3-dihydroxy-DL-tyrosine
  • Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo.
  • DL-threo-Dihydroxyphenylserine
  • DL-Tyrosine, b,3-dihydroxy-, threo-
  • D-Tyrosine, β,3-dihydroxy-, (βS)-rel-
  • Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo- (8CI)
  • threo-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic acid
  • ((2RS,3RS)-2-Amino-3-(3,4-dihydroxy-phenyl)-3-hydr
  • DL-threo-3,4-Dihydroxyphenylserine, DL-threo-DOPS
  • (±)-threo-DOPS
  • (±)-β,3-Dihydroxy-threo-tyrosine
  • rac-(2S*,3R*)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic acid
  • β,3-Dihydroxy-DL-threo-tyrosine
  • DL-threo-Droxidopa
  • (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID
  • (+/-)-THREO-DIHYDROXYPHENYLSERINE (+/-)- THREO-DOPS
  • DL-THREO-B-(3,4-DIHYDROXYPHENYL)SERINE
  • Droxidopa Impurity 4
  • Beta-D,L-(3,4-Dihydroxyphenyl)-Serine
  • Droxidopa Impurity 10 (DL-threo-Droxidopa)
  • Droxidopa Impurity 10
  • (βS)-rel-β,3-Dihydroxy-D-tyrosine
  • (2RS,3RS)-2-AMino-3-(3,4-dihydroxy-phenyl)-3-hydroxy-propionic acid, DL-DOPS, DL-Droxidopa
  • H-DL-b-(3,4-Dihydroxyphenyl)-DL-Ser-OH
  • Droxidopa DL-threo Impurity
  • rel-(2R,3S)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
  • 3-D,L-(3,4-dihydroxy-phenyl-)-serine
  • 3916-18-5
  • 3916-28-5
  • Amines
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals