Dihydrocaffeic acid

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Dihydrocaffeic acid

Product Name: Dihydrocaffeic acid
CAS No.: 1078-61-1
Chemical Name: Dihydrocaffeic acid
Synonyms: NSC 407275;NSC 624007;Hydrocaffeate;HYDROCAFFEIC ACID;3-propionic acid;DIHYDROCAFFEIC ACID;DIHYDROCAFFEIC ACID(RG);3,4-DIHYDROCAFFEIC ACID;13C6]-Dihydrocaffeic acid;4-Dihydroxyhydrocinnamic acid
CBNumber: CB1439090
Molecular Formula: C9H10O4
Formula Weight: 182.17
MOL File: 1078-61-1.mol

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Dihydrocaffeic acid Property

Melting point:: 136-139 °C(lit.)
Boiling point:: 418℃
Density: 1.398
Flash point:: 220℃
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.75±0.10(Predicted)
color: Pale Beige to Pale Brown
Water Solubility: Slightly soluble in water.
BRN: 2213449
InChI: InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
InChIKey: DZAUWHJDUNRCTF-UHFFFAOYSA-N
SMILES: C1(CCC(O)=O)=CC=C(O)C(O)=C1
LogP: 0.115 (est)
CAS DataBase Reference: 1078-61-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: MW5143500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 102601
Product name: 3,4-Dihydroxyhydrocinnamic acid
Purity: 98%
Packaging: 2.5G
Price: $55.56
Updated: 2024/03/01

Sigma-Aldrich

Product number: 102601
Product name: 3,4-Dihydroxyhydrocinnamic acid
Purity: 98%
Packaging: 10G
Price: $237
Updated: 2024/03/01

Sigma-Aldrich

Product number: 102601
Product name: 3,4-Dihydroxyhydrocinnamic acid
Purity: 98%
Packaging: 25G
Price: $463
Updated: 2024/03/01

Alfa Aesar

Product number: A11638
Product name: 3-(3,4-Dihydroxyphenyl)propionic acid, 98+%
Packaging: 5g
Price: $60.5
Updated: 2024/03/01

Alfa Aesar

Product number: A11638
Product name: 3-(3,4-Dihydroxyphenyl)propionic acid, 98+%
Packaging: 25g
Price: $186
Updated: 2024/03/01

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Dihydrocaffeic acid Chemical Properties,Usage,Production

Description

Dihydrocaffeic acid is a polyphenol that has diverse biological activities, including antioxidant, neuroprotective, and enzyme inhibitory properties. Dihydrocaffeic acid scavenges ABTS (; IC₅₀ = 81.86 μg/ml) and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ; IC₅₀ = 192.86 μg/ml) radicals and increases the survival of RGC-5 mouse retinal ganglion cells under hypoxic conditions and in the presence of S-nitroso-N-acetyl-D,L-penicillamine (SNAP; ) in a concentration-dependent manner. It also decreases endothelial nitric oxide synthase (eNOS) activity in EA.hy926 human endothelial cells in a concentration-dependent manner. In vivo, dihydrocaffeic acid (30 mg/kg) decreases infarct size in a rat model of transient ischemia induced by middle cerebral artery occlusion (MCAO).

Chemical Properties

Brown Solid

Uses

Dihydrocaffeic Acid is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective activity. Dihydrocaffei c Acid is a metabolite of Caffeic Acid (C08000) with potent antioxidant properties.

Uses

3-(3,4-Dihydroxyphenyl)propionic acid it can be used to produce 3-(3,4-dihydroxy-phenyl)-propionic acid octyl ester by heating.

Definition

ChEBI: A monocarboxylic acid that is 3-phenylpropionic acid substituted by hydroxy groups at positions 3 and 4. It is a metabolite of caffeic acid and exhibits antioxidant activity.

Dihydrocaffeic acid Preparation Products And Raw materials

Raw materials

Palladium hydroxide Triethyl phosphonoacetate tert-Butanol Tosylmethyl isocyanide Tetrahydrofuran Ammonium chloride Ethyl acetate Protocatechualdehyde Magnesium sulfate Potassium

Preparation Products

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View Lastest Price from Dihydrocaffeic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Dihydrocaffeic acid 1078-61-1
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-04-24

Hebei Weibang Biotechnology Co., Ltd

Product: 3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID 1078-61-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-04

Hebei Chuanghai Biotechnology Co,.LTD

Product: Dihydrocaffeic acid 1078-61-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100000Ton
Release date: 2024-08-16

1078-61-1, Dihydrocaffeic acidRelated Search:

Methyldopa DL-DOPA 3-(3,4,5-TRIMETHOXYPHENYL)PROPIONIC ACID 3-(3,4-METHYLENEDIOXYPHENYL)PROPIONIC ACID 3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID CINOXACIN Oxolinic acid (2S)-2-Amino-3-(3,4-dimethoxyphenyl)-2-methyl-propanoic acid 3,4-Dimethoxyhydrocinnamic acid Dihydrocaffeic acid Levodopa (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID BETANIN ETHYL 3-(3,4,5-TRIMETHOXYPHENYL)PROPIONATE (R)-2-Amino-3-(3,4-dihydroxyphenyl)propionic acid DROXIDOPA DL-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid (R)-2-Hydroxy-3-(3,4-dihydroxyphenyl)propionic acid

3-(3,4-dihydroxyphenyl)propanoate

3-(3,4-Dihydroxyphenyl)propionic acid, Hydrocaffeic acid

3-(3,4-Dihydroxyphenyl)propionic acid, 98+%

DIHYDROCAFFEIC ACID(RG)

3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID

3,4-DIHYDROXYHYDROCINNAMIC ACID

3,4-DIHYDROCAFFEIC ACID

BETA-(3,4-DIHYDROXYPHENYL) PROPIONIC ACID

DIHYDROCAFFEIC ACID

HYDROCAFFEIC ACID

3,4-dihydroxy-benzenepropanoicaci

3,4-dihydroxybenzenepropanoicacid

3,4-dihydroxy-hydrocinnamicaci

3,4-Dihydroxyhydrocinnamic acid~Hydrocaffeic acid

3,4-dihydroxyphenylpropionic acid

3-(3,4-Dihydroxyphenyl)propanoic acid

3-propionic acid

3,4-Dihydroxybenzenepropionic Acid

3,4-DihydroxydihydrocinnaMic Acid

NSC 407275

NSC 624007

3,4-Dihydroxy-beta-phenylpropionic acid

4-Dihydroxyhydrocinnamic acid

Benzenepropanoic acid, 3,4-dihydroxy-

3-(3,4-dihydroxyphenyl)propanoicaci

3-(3,4-DIHYDROXYPHENYL)PROPIONIC ACID USP/EP/BP

3- (3, 4-DIHYDROXYPHENYL) Propio Nic Acid / Dihydrocaffeic Acid Powder CAS 1078-61-1

13C6]-Dihydrocaffeic acid

Hydrocaffeate

1078-61-1

HO2C6H3CH2CH2CO2H

Carboxylic Acids

Carbonyl Compounds

Building Blocks

Organic Building Blocks

Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals

Aromatic Cinnamic Acids, Esters and Derivatives