ChemicalBook > CAS DataBase List > Methyl pyruvate

Methyl pyruvate

Product Name
Methyl pyruvate
CAS No.
600-22-6
Chemical Name
Methyl pyruvate
Synonyms
Propanoic acid, 2-oxo-, methyl ester;METHYL 2-OXOPROPANOATE;PAME;ksby;PYR ME;METHYL PYRUVATE;Methyl pyruyate;MethylPyruvate>Methylpyruvate,96%;Methyl acetoformate
CBNumber
CB8405108
Molecular Formula
C4H6O3
Formula Weight
102.09
MOL File
600-22-6.mol
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Methyl pyruvate Property

Melting point:
-22 °C
Boiling point:
134-137 °C (lit.)
Density 
1.13 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.404(lit.)
Flash point:
103 °F
storage temp. 
2-8°C
solubility 
ethanol: soluble1.1g/10 mL, clear, colorless to almost colorless
form 
liquid
color 
Yellow
Water Solubility 
Soluble in chloroform, methanol, ether, alcohol. Slightly soluble in water.
Merck 
14,8021
BRN 
1361953
LogP
-0.159 (est)
CAS DataBase Reference
600-22-6(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, 2-oxo-, methyl ester(600-22-6)
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Safety

Hazard Codes 
Xi,F
Risk Statements 
10
Safety Statements 
23-24/25-16
RIDADR 
UN 3272 3/PG 3
WGK Germany 
3
10-21
HazardClass 
3
PackingGroup 
III
HS Code 
29183000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
371173
Product name
Methyl pyruvate
Purity
90%, technical grade
Packaging
25g
Price
$38.9
Updated
2024/03/01
Sigma-Aldrich
Product number
371173
Product name
Methyl pyruvate
Purity
90%, technical grade
Packaging
100g
Price
$45.2
Updated
2024/03/01
TCI Chemical
Product number
P0580
Product name
Methyl Pyruvate
Purity
>97.0%(GC)
Packaging
25mL
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
P0580
Product name
Methyl Pyruvate
Purity
>97.0%(GC)
Packaging
500mL
Price
$186
Updated
2024/03/01
Alfa Aesar
Product number
A13966
Product name
Methyl pyruvate, 98%
Packaging
25g
Price
$35.65
Updated
2024/03/01
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Methyl pyruvate Chemical Properties,Usage,Production

Chemical Properties

Methyl pyruvate is a clear, light yellow, and flammable liquid.

Uses

Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increases free calcium ion concentration in the cytosol of pancreatic cells. It is used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

Uses

Methyl pyruvate may be used to investigate the adsorption and reactivity of methyl pyruvate on Pt{111}. It may be used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

Definition

ChEBI: Methyl pyruvate is a pyruvate ester resultinf grom the formal condensation of the carboxy group of pyruvic acid with the hydroxy group of methanol. It is a pyruvate ester and a methyl ester. It derives from a pyruvic acid.

Preparation

Methyl pyruvate has been prepared from the silver salt of pyruvic acid and methyl iodide; from the free acid, by the ethanol-vapor method without a catalyst, by azeotropic removal of the water produced by the reaction of methanol in the presence of p-toluenesulfonic acid (the present method), and by refluxing with methanol in ethylene dichloride using ethanesulfonic acid as a catalyst (73% yield). Pyruvic esters have also been prepared by the catalytic dehydrogenation of lactic acid esters and by the oxidation of ethyl lactate with potassium permanganate.
DOI: 10.15227/orgsyn.024.0072

General Description

Methyl pyruvate is a pyruvic ester. Surface conditions during Pt/silica EUROPT-1 modified by cinchonidine catalyzed by enantioselective hydrogenation of methyl pyruvate to R-(+)-methyl lactate were investigated. Enantioselective hydrogenation of methyl pyruvate over finely dispersed polyvinylpyrrolidone-stabilized and the corresponding alumina-supported iridium clusters modified with cinchonidine was studied. The molecular orientation and conformation of methyl pyruvate on Ni(111) surface has been investigated in the temperature range 105-220K. Methyl pyruvate is reported to stimulate insulin secretion in vitro and in vivo.

Methyl pyruvate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl pyruvate Suppliers

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View Lastest Price from Methyl pyruvate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Methyl pyruvate 600-22-6
Price
US $56.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-21
Hebei Miaoyin Technology Co.,Ltd
Product
Methyl pyruvate 600-22-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000
Release date
2023-04-06
airuikechemical co., ltd.
Product
Methyl pyruvate 600-22-6
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-07

600-22-6, Methyl pyruvateRelated Search:


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