2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE

Product Name: 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
CAS No.: 139047-55-5
Chemical Name: 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
Synonyms: 3-MPPI;2-PMDQ;2 PMDQ,2PMDQ;2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-
CBNumber: CB8409227
Molecular Formula: C21H23N5O
Formula Weight: 361.44
MOL File: Mol file

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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Property

Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 10 mM in DMSO and in ethanol
form: Powder
pka: 13.74±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P637005
Product name: 2-PMDQ
Packaging: 10mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 254372
Product name: 2-PMDQ
Packaging: 10mg
Price: $418
Updated: 2021/12/16

TRC

Product number: P637005
Product name: 2-PMDQ
Packaging: 50mg
Price: $670
Updated: 2021/12/16

ApexBio Technology

Product number: B6382
Product name: 2-PMDQ
Packaging: 50mg
Price: $723
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0004260
Product name: 2-PMDQ
Purity: 95.00%
Packaging: 5MG
Price: $501.89
Updated: 2021/12/16

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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Chemical Properties,Usage,Production

Uses

2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects.

Definition

ChEBI: 2-[(4-phenyl-1-piperazinyl)methyl]-3,6-dihydro-2H-imidazo[1,2-c]quinazolin-5-one is a member of piperazines.

Biological Activity

Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM).

2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Suppliers

China 14 United Kingdom 2 United States 4 Global 20

3B Pharmachem (Wuhan) International Co.,Ltd.

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139047-55-5, 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONERelated Search:

2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE

2-PMDQ

3-MPPI

Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-

2 PMDQ,2PMDQ

139047-55-5