ChemicalBook > CAS DataBase List > 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE

2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE

Product Name
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
CAS No.
139047-55-5
Chemical Name
2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
Synonyms
3-MPPI;2-PMDQ;2 PMDQ,2PMDQ;2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE;Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-
CBNumber
CB8409227
Molecular Formula
C21H23N5O
Formula Weight
361.44
MOL File
Mol file
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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Property

Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 10 mM in DMSO and in ethanol
form 
Powder
pka
13.74±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P637005
Product name
2-PMDQ
Packaging
10mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
254372
Product name
2-PMDQ
Packaging
10mg
Price
$418
Updated
2021/12/16
TRC
Product number
P637005
Product name
2-PMDQ
Packaging
50mg
Price
$670
Updated
2021/12/16
ApexBio Technology
Product number
B6382
Product name
2-PMDQ
Packaging
50mg
Price
$723
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004260
Product name
2-PMDQ
Purity
95.00%
Packaging
5MG
Price
$501.89
Updated
2021/12/16
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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Chemical Properties,Usage,Production

Uses

2-PMDQ is an analog of Ketanserin with beneficial hemodynamic effects in portal hypertensive rats. Anti-hypertensive effects.

Definition

ChEBI: 2-[(4-phenyl-1-piperazinyl)methyl]-3,6-dihydro-2H-imidazo[1,2-c]quinazolin-5-one is a member of piperazines.

Biological Activity

Very potent ligand for α 1 sites (K i for displacement of prazosin = 0.2 nM). Also binds to 5-HT 1A sites (K i = 50 nM).

2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66

139047-55-5, 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONERelated Search:


  • 2-[(4-PHENYLPIPERAZIN-1-YL)METHYL]-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLIN-5(6H)-ONE
  • 2-PMDQ
  • 3-MPPI
  • Imidazo[1,2-c]quinazolin-5(3H)-one, 2,6-dihydro-2-[(4-phenyl-1-piperazinyl)methyl]-
  • 2 PMDQ,2PMDQ
  • 139047-55-5