4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE

Product Name: 4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE
CAS No.: 50432-68-3
Chemical Name: 4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE
Synonyms: 4-Chloro-1-methyl-imidazo[4,5-c]pyridine;4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE;1H-Imidazo[4,5-c]pyridine, 4-chloro-1-methyl-
CBNumber: CB8418894
Molecular Formula: C7H6ClN3
Formula Weight: 167.6
MOL File: 50432-68-3.mol

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4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Property

Melting point:: 168-170 °C(Solv: cyclohexane (110-82-7); ethyl acetate (141-78-6))
Boiling point:: 331.8±45.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 3.13±0.30(Predicted)
Appearance: Light brown to black Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C602088
Product name: 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 072550
Product name: 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine
Purity: 95+%
Packaging: 500mg
Price: $58
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC142178
Product name: 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine
Packaging: 10g
Price: $782
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-B6
Product name: 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine
Packaging: 1g
Price: $425
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC142178
Product name: 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine
Packaging: 5G
Price: $460
Updated: 2021/12/16

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4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Chemical Properties,Usage,Production

Synthesis

2770-01-6

74-88-4

50432-68-3

87034-78-4

NaH (78 mg, 1.95 mmol, 60% w/w oil solution) was slowly added to a solution of 4-chloro-3H-imidazo[4,5-c]pyridine (100 mg, 0.65 mmol) in DMF (3 mL) at 0 °C under nitrogen protection. The reaction mixture was stirred at 0 °C for 40 min. Subsequently, iodomethane (277 mg, 1.95 mmol) was added at the same temperature. The reaction mixture was warmed to room temperature and stirring was continued for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated aqueous NH4Cl solution and extracted with ethyl acetate (20 mL x 3). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The residue was purified by preparative HPLC to afford 4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine (58, 40.3 mg) and 4-chloro-3-methyl-3H-imidazo[4,5-c]pyridine (59, 41.0 mg), both yellow oils, respectively.LRMS (m/z): [M+H]+ calculated values 168.2, 170.2; measured values 168.0, 170.2.

References

[1] Patent: WO2016/101119, 2016, A1. Location in patent: Page/Page column 99; 100

4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Suppliers

China 63 India 1 United Kingdom 1 United States 10 Global 75

Pure Chemistry Scientific Inc.

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50432-68-3, 4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINERelated Search:

1-(2,3,5-TRI-O-ACETYL-B-D-RIBOFURANOSYL)-4,6-DICHLOROIMIDAZO[4,5-C]PYRIDINE AKOS 90493 4-chloro-1-(1-methylethyl)-1H-imidazo[4,5-c]pyridine 4-chloro-1-(2-ethoxyethyl)-1H-imidazo[4,5-c]pyridine 2-BROMO-4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE 2-(4-chloro-1H-imidazo[4,5-c]pyridin-1-yl)ethanol 2-BROMO-4-CHLORO-1,6-DIMETHYL-1H-IMIDAZO[4,5-C]PYRIDINE 2-(4-chloro-1H-imidazo[4,5-c]pyridin-1-yl)-N,N-dimethylethanamine 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 1-BENZYL-2-BROMO-4-CHLORO-6-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE 3-(4-CHLORO-6-METHYL-1H-IMIDAZO[4,5-C]PYRIDIN-1-YL)PROPAN-1-OL 4-CHLORO-1,6-DIMETHYL-1H-IMIDAZO[4,5-C]PYRIDINE 4-CHLORO-1-(2-DEOXY-BETA-D-ERYTHROPENTOFURANOSYL)-1H-IMIDAZO[4,5-C]PYRIDINE 4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE

4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE

4-Chloro-1-methyl-imidazo[4,5-c]pyridine

1H-Imidazo[4,5-c]pyridine, 4-chloro-1-methyl-

50432-68-3

Heterocycle-Pyridine series