ChemicalBook > CAS DataBase List > 4-Allylanisole

4-Allylanisole

Product Name
4-Allylanisole
CAS No.
140-67-0
Chemical Name
4-Allylanisole
Synonyms
ESTRAGOLE;METHYL CHAVICOL;1-Allyl-4-methoxybenzene;Terragon;Estragol;P-ALLYLANISOLE;1-METHOXY-4-(2-PROPEN-1-YL)BENZENE;Esdragol;Tarragon;Esdragole
CBNumber
CB8429687
Molecular Formula
C10H12O
Formula Weight
148.2
MOL File
140-67-0.mol
More
Less

4-Allylanisole Property

Melting point:
25°C
Boiling point:
215-216 °C (lit.)
Density 
0.965 g/mL at 25 °C (lit.)
vapor pressure 
82-101hPa at 20-37.8℃
FEMA 
2411 | ESTRAGOLE
refractive index 
n20/D 1.521(lit.)
Flash point:
178 °F
storage temp. 
Sealed in dry,2-8°C
solubility 
0.178g/l
form 
Liquid
color 
Clear colorless
Specific Gravity
0.965
Odor
at 10.00 % in propylene glycol. sweet sassafrass anise spice green herbal fennel
Odor Type
anisic
Water Solubility 
177.8mg/L(25 ºC)
Merck 
14,3705
JECFA Number
1789
BRN 
1099454
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents.
LogP
3.4 at 25-35℃ and pH7
CAS DataBase Reference
140-67-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-methoxy-4-(2-propenyl)-(140-67-0)
EPA Substance Registry System
Estragole (140-67-0)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-38-43-68-40
Safety Statements 
26-36/37
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
BZ8225000
TSCA 
Yes
HS Code 
29093090
Hazardous Substances Data
140-67-0(Hazardous Substances Data)
Toxicity
LD50 in rats, mice (mg/kg): 1820, 1250 orally (Jenner)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H341Suspected of causing genetic defects

H351Suspected of causing cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W241105
Product name
4-Allylanisole
Purity
≥98%, FCC
Packaging
1kg
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
W241105
Product name
4-Allylanisole
Purity
≥98%, FCC
Packaging
5kg
Price
$720
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL82205
Product name
Estragole
Purity
phyproof? Reference Substance
Packaging
100MG
Price
$250
Updated
2023/06/20
Sigma-Aldrich
Product number
05818
Product name
4-Allylanisole
Purity
analytical standard
Packaging
1ml
Price
$37.4
Updated
2022/05/15
TCI Chemical
Product number
A0702
Product name
4-Allylanisole
Purity
>98.0%(GC)
Packaging
10g
Price
$24
Updated
2024/03/01
More
Less

4-Allylanisole Chemical Properties,Usage,Production

Chemical Properties

colourless liquid with an aniseed smell

Chemical Properties

Basil oil, methyl chavicol (estragole)-type (Réunion type, exotic type) is obtained by steam distillation of the flowering tops or whole plants of Ocimum basilicum L. (Lamiaceae), which was formerly grown in Réunion and Madagascar. Today, the oil is produced in India and Vietnam on relatively large scale (～100 and 30 t/yr, respectively) and also in Egypt, but in small quantities. It is a light yellow liquid with a fresh, green, spicy odor characteristic of methyl chavicol (estragole).
d2020 0.948–0.970; n20D 1.5100–1.5200; α20D ?1°to +2°; solubility: 1 vol in ≤7 vol 80% ethanol; content by GC: methyl chavicol 75–87%; linalool 0.5–3%(data for the classical “exotic” type; Indian types may contain up to ～20% linalool).

Chemical Properties

Estragole has an odor reminiscent of anise with a corresponding sweet taste (differing from anethole)

Chemical Properties

Herbaceous plant native to eastern and central Europe; it prefers shady growing sites. It grows 30 to 80 cm (12 to 31 in.) tall, with roots clustered in bundles, a branched stalk, alternate leaves and yellow flowers. Leaves are fragrant and anise-flavored. The plant flowers from July to August. The parts used are the flowering tops and leaves. Tarragon has a sweet, spicy odor and a sweet, anisic, fresh, green flavor reminiscent of basil and anise. This herb is commonly used to flavor vinegar and to season meats, soups, vegetable and fish dishes.

Occurrence

Reported found in anise oil.

Uses

insect atttractant, skin irritant, carcinogen

Uses

4-Allylanisole has been used as a reference standard for the analysis of 4-allylanisole in essential oils by high performance liquid chromatography (HPLC) equipped with fluorometric detector and in emissions from live vegetation by solid-phase microextraction (SPME) combined with proton transfer reaction mass spectrometry (PTR-MS). It may be used as a reference standard for the determination of 4-allylanisole in food products by simultaneous distillation-extraction (SDE) followed by analyses using capillary gas chromatography (GC)-flame ionization detector (FID) and GC-MS.

Uses

In perfumes and as flavor in foods and liqueurs.

Definition

ChEBI: Estragole is an olefinic compound.

Preparation

Obtained by fractional distillation of the oil of turpentine or by treating a solution of the same oil in ether with an aqueous solution of mercuric acetate and subsequently heating the aqueous phase with zinc and sodium hydroxide; forms allyl bromide and magnesium p-methoxy phenate in ether.

Composition

The herb is reported to contain polyacetylenic compounds (capillene; phenyl-1,3-pentadiyne; acetylenic alcohol and its glucoside; capillone and dehydrofalcarinone); coumarinic and isocoumarinic derivatives (artemidinol, artemidiol, scopoletine, herciarine); alcohols (9-hydroxygeraniol; 4-methoxybenzyl alcohol); aldehyde (CoE, 2000).

Taste threshold values

Taste characteristics at 10 ppm: sweet, licorice, phenolic, weedy, spice, celery-like

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 1748, 1996 DOI: 10.1021/jo9518314
Synthesis, p. 701, 1983

General Description

Colorless liquid with odor of anise. Insoluble in water. Isolated from rind of persea gratissima grath. and from oil of estragon. Found in oils of Russian anise, basil, fennel turpentine, tarragon oil, anise bark oil.

Air & Water Reactions

Forms azeotropic mixtures with water. . Insoluble in water.

Reactivity Profile

4-Allylanisole may react vigorously with strong oxidizing agents. Can react exothermically with reducing agents (such as alkali metals and hydrides) to release gaseous hydrogen. May react exothermically with both acids and bases.

Health Hazard

ACUTE/CHRONIC HAZARDS: 4-Allylanisole is an irritant.

Fire Hazard

4-Allylanisole is combustible.

Safety Profile

Moderate acute toxicity by many routes. A skin irritant. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALLYL COMPOUNDS. A spice used in foods, liqueurs, and perfumes.

4-Allylanisole Preparation Products And Raw materials

Raw materials

Turpentine oil Allyl bromide Tarragon Oil

Preparation Products

cis-Anethol
More
Less

4-Allylanisole Suppliers

Americas 1 Australia 1 Belgium 1 Brazil 2 Canada 1 China 215 Europe 2 France 3 Germany 6 India 55 Italy 1 Japan 3 Mexico 1 South Africa 1 South Korea 1 Spain 4 Switzerland 3 United Kingdom 12 United States 70 Global 383
Condice Chemical (Hubei) Co., Ltd.
Tel
18064039730
Email
3127859172@qq.com
Country
China
ProdList
2831
Advantage
58
Wuhan canos Technology Co., Ltd
Tel
027-83238443 15327105076
Fax
027-83238443
Email
926254131@qq.com
Country
China
ProdList
3011
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
jiliang chemicals
Tel
21-62165282 15801962796;
Fax
021 61153784
Email
bidingchem@163.com
Country
China
ProdList
1174
Advantage
60
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7856
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
Chengdu Herbpurify Co.Ltd.
Tel
18302802153 18981717076
Fax
086-28-85377358
Email
2355253616@qq.com
Country
China
ProdList
1104
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd.
Tel
13720616393；029-84385017-8003 13720616393
Fax
029-84385017
Email
sales@pioneerbiotech.com
Country
China
ProdList
1065
Advantage
56
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Nanjing Duolong Bio-tech Co.,Ltd.
Tel
18905173768
Fax
025-83263139
Email
sales@dolonchem.com
Country
China
ProdList
2297
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31557
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5115
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6120
Advantage
58
Guangzhou Kafen Biotech Co.,Ltd
Tel
18029243487 2355327168
Fax
020-31121510
Email
gy@yccreate.com
Country
China
ProdList
4753
Advantage
55
Shanghai Witofly Chemical Co. ,Ltd.
Tel
021-021-50630626 18964684208
Email
sales@witofly.com
Country
China
ProdList
1150
Advantage
55
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9980
Advantage
55
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
9175
Advantage
60
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
9998
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Zhuhai JiaYi Biological Technology Co., Ltd.
Tel
18578209868 2355327026
Fax
18578209868 QQ：2355327026
Email
steroidbest@hotmail.com
Country
China
ProdList
6504
Advantage
58
Shanghai Standard Technology Co.,Ltd.
Tel
021-57127007-6622 15618937986
Fax
+86 (21) 5132-0077
Email
zhaok@nature-standard.com
Country
China
ProdList
3928
Advantage
58
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15952
Advantage
58
Hefei Yaogu Biological Technology Co., Ltd.
Tel
0086-0551-62993905
Fax
0086-0551-62993905
Email
info@hxygmall.com
Country
China
ProdList
3374
Advantage
58
More
Less

View Lastest Price from 4-Allylanisole manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
4-Allylanisole 140-67-0
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200000kg
Release date
2024-04-26
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
ETHYL OLEATE 140-67-0
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200000kg
Release date
2024-04-26
Hebei Duling International Trade Co. LTD
Product
4-Allylanisole 140-67-0
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
30 tons
Release date
2023-03-31

140-67-0, 4-AllylanisoleRelated Search:

Methyl eugenol Allyl chloride Benzene Allyl bromide Allyl glycidyl ether Sodium allylsulfonate Diallylamine LUTEONE 4'-METHOXYCHALCONE 2',4-DIHYDROXY-4',6'-DIMETHOXYCHALCONE Genistin Colchicine EUPATORIN-5-METHYL ETHER Safrole AFLATOXIN G1 3,7,3',4'-TETRAMETHYLGOSSYPETIN Hesperidin methylchalcone Diosmin

  • Anisole, p-allyl-
  • Chavicol, methyl-
  • Chavicol, O-methyl-
  • Chavicyl methyl ether
  • Esdragol
  • Esdragole
  • Esdragon
  • Estragol
  • Estragol (Methylchavicol)
  • Ether, p-allylphenyl methyl
  • femanumber2411
  • Isoanethole
  • NCI-C60946
  • o-methyl-chavico
  • p-allyl-anisol
  • p-Allylmethoxybenzene
  • p-Allylphenyl methyl ether
  • p-Methoxyallylbenzene
  • Tarragon
  • Terragon
  • METHYL CHAVICOL
  • FEMA 2411
  • ESTRAGOLE
  • CHAVICOL METHYL ETHER
  • 1-METHOXY-4-(2-PROPEN-1-YL)BENZENE
  • 1-METHOXY-4-(2-PROPENYL)BENZENE
  • 4-ALLYLANISOLE
  • 4-ALLYL-1-METHOXYBENZENE
  • 4-METHOXYALLYLBENZENE
  • 3-(4-METHOXYPHENYL)-1-PROPENE
  • P-ALLYLANISOLE
  • 1-Allyl-4-methoxybenzene
  • 1-allyl-4-methoxy-benzene
  • 1-methoxy-4-(2-propenyl)-benzen
  • 3-(p-Methoxyphenyl)propene
  • 4-allyl
  • 4-Allylanisol
  • 4-Allylmethoxybenzene
  • Artemisia brain
  • Natural 4-Allylanisole
  • 4-AL
  • ESTRAGOLE (METHYL CHAVICOL)
  • METHYL CHAVICOL (ESTRAGOLE)
  • 4-ALLYLANISOLE 98+% FCC
  • 4-ALLYLANISOLE, TERPENE STANDARD FOR GC
  • estragole,(1-methoxy)-4-(2-propenyl)benzene,4-allylanisole
  • Benzene, 1-methoxy-4-(2-propenyl)-
  • PARA-ALLYLANISOLE
  • ALLYLANISOLE
  • Estragole 4-Methoxyallylbenzene
  • O-Methyl-chavicol
  • p-Allylpheny methyl ether
  • ESTRAGOLE WITH GC
  • 4-ALLYLANISOLE, 98% (SEE 2686)
  • ESTRAGOLE (SEE 1704)
  • METHYL CHAVICOL, NATURAL
  • METHYL CHAVICOL, SYNTHETIC
  • Chavicol methyl ether, Estragole