Testosterone enanthate
Indications and Usage Drug Metabolism Clinical Research Adverse reactions- Product Name
- Testosterone enanthate
- CAS No.
- 315-37-7
- Chemical Name
- Testosterone enanthate
- Synonyms
- Enanthate;TESTOSTERONE ENANTATE;Testosterone Enanthat;Testosterone Ethanate;Testostroval;Testosterone oenanthate;17-[(1-Oxoheptyl)oxy]androst-4-en-3-one;Testosterone Enanthate (Test e ,TE)-1 gram(2);Factory hot selling Testosterone Enanthate cas315-37-7 CAS NO.315-37-7;Everone
- CBNumber
- CB8448727
- Molecular Formula
- C26H40O3
- Formula Weight
- 400.59
- MOL File
- 315-37-7.mol
Testosterone enanthate Property
- Melting point:
- 34-39°C
- alpha
- 77 º
- Boiling point:
- 463.22°C (rough estimate)
- Density
- 1.0562 (rough estimate)
- refractive index
- 1.4700 (estimate)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, very soluble in anhydrous ethanol, freely soluble in fatty oils.
- InChI
- InChI=1/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/s3
- InChIKey
- VOCBWIIFXDYGNZ-IXKNJLPQSA-N
- SMILES
- [C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCCCCC |&1:0,10,12,16,18,21,r|
- CAS DataBase Reference
- 315-37-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Testosterone enanthate(315-37-7)
Safety
- Hazard Codes
- T
- Risk Statements
- 45-63
- Safety Statements
- 53-22-36/37/39-45
- WGK Germany
- 3
- RTECS
- XA3080000
- HS Code
- 2937290000
- Toxicity
- man,TDLo,intramuscular,7519mg/kg/5W- (7519mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEA,New England Journal of Medicine. Vol. 308, Pg. 508, 1983.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H350May cause cancer
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- T3006
- Product name
- Testosterone enanthate
- Purity
- analytical standard
- Packaging
- 1g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- 1648004
- Product name
- Testosterone enanthate
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $532
- Updated
- 2024/03/01
- Product number
- 22546
- Product name
- Testosterone Enanthate
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 22546
- Product name
- Testosterone Enanthate
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- Y0001317
- Product name
- Testosterone enantate for system suitability
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0001317
- Price
- $150
- Updated
- 2024/03/01
Testosterone enanthate Chemical Properties,Usage,Production
Indications and Usage
Testosterone enanthate is a type of androgen drug, and it is a synthetic compound of testosterone proprionate and testosterone enantate. Its effects are the same as those of testosterone acetate, which include promoting the development of male sex organs and secondary sex characteristics and resisting estrogen. It also has protein assimilating effects, which allow it to help muscle growth and weight gain. Testosterone enanthate can inhibit the pituitary gland and promote sex hormone secretion, thus decreasing the endogenous testosterone secreted by Leydig cells, which achieves the purpose of stopping spermatogenesis.
Testosterone enanthate can be used as a long-term male birth control drug. It is clinically used to treat male hypogonadism and gonadal insufficiency, sex organ hypogenesis, infertility, eunuchism, and cryptorchidism. It can also be used to treat female dysfunctional uterine bleeding, menopausal syndrome, breast cancer and uterine cancer. It can also treat cirrhosis, aplastic anemia, osteoporosis and other consumptive diseases.
Drug Metabolism
After injection, it creates a blood concentration higher than the physiological level, and then blood concentration decreases rapidly.
Clinical Research
In a trial that injected monkeys with testosterone enanthate every week, the monkeys’ sperm cells began experiencing apoptosis in a week, with apoptosis rates peaking in the fifth week. A clinical trial with 308 participants also showed that testosterone enanthate’s birth-control effects are much more effective on Asian men than on Caucasian men, as over 95% of Asian men achieved azoospermia, while only 40-70% of Caucasian men did.
A trial of over 100 volunteers showed that weekly muscle injections of 250mg led to most men developing azoospermia or severe ogliospermia in 10 weeks, and that sperm count could recover after ceasing injection for a certain period of time. If the injection intervals are extended to over 10-12 days, even increasing dosage will not have desired effects. Testosterone enanthate only needs to be injected once a week, which is an advantage over testosterone acetate.
Adverse reactions
Large dosages or extended use can cause water and sodium retention and edema. Young women may exhibit virilism, with characteristics including deepened voice, hair growth, acne, clitoral hypertrophy, etc. Not to be used by patients with prostatic cancer or pregnant patients. Should be used with caution by patients with prostate hypertrophy and liver and kidney dysfunction. When treating breast cancer, drug usage should be stopped immediately if hypercalcemia is detected.
Description
Testosterone enanthate (Item No. 22546) is an analytical reference standard categorized as an anabolic androgenic steroid. It is an ester of the naturally occurring androgen, testosterone (Item Nos. 15645 | ISO60154) with a longer half-life. Formulations containing testosterone enanthate have been tested for use in hypogonadism and as a potential male contraceptive. Formulations containing it have been associated with higher levels of total cholesterol, low density lipoproteins, and triglycerides and lower levels of high density lipoproteins. Anabolic steroids, including testosterone enanthate, have been used to enhance physical performance in racehorses and athletes, and methods to detect steroids, their derivatives, and their metabolites have been developed. This product is intended for research and forensic applications.
Chemical Properties
White or yellowish-white, crystalline powder.
Originator
Delatestryl,Squibb,US,1954
Uses
Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.
Definition
ChEBI: Testosterone enanthate is a heptanoate ester and a sterol ester. It has a role as an androgen. It is functionally related to a testosterone.
Manufacturing Process
A mixture of testosterone, pyridine and oenanthic acid anhydride is heated for 1 1/2 hours to 125°C. The cooled reaction mixture is decomposed with water while stirring and cooling. After prolonged standing at a temperature below room temperature, the whole is extracted with ether and the ethereal solution is washed consecutively with dilute sulfuric acid, water, 5% sodium hydroxide solution, and again with water. The crude ester remaining on evaporation of the dried ether solution, after recrystallization from pentane, melts at 36° to 37.5°C.
Therapeutic Function
Androgen
Testosterone enanthate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Testosterone enanthate manufacturers
- Product
- testosterone enanthate 315-37-7
- Price
- US $30.00-10.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 200ton
- Release date
- 2024-03-14
- Product
- Testosterone Enanthate 315-37-7
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-15
- Product
- Testosterone enanthate 315-37-7
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-16