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CDAP

Product Name
CDAP
CAS No.
59016-56-7
Chemical Name
CDAP
Synonyms
CDAP;4-(dimethylamino)pyridin-1-ium-1-carbonitrile;N-Cyano-4-diMethylaMinopyridiniuM tetrafluoroborat;1-CYANO-4-DIMETHYLAMINO-PYRIDINIUM TETRAFLUOROBORATE;N-CYANO-4-DIMETHYLAMINOPYRIDINIUM TETRA FLUOROBORATE;N-cyanogen-4-dimethylamino-pyridine tetrafluoroborate;1-Cyano-4-(dimethylamino)pyridin-1-ium tetrafluoroborate;1-Cyano-4-dimethylaminopyridinium tetrafluoroborate,97+%;CDAP N-Cyano-4-dimethylaminopyridinium tetrafluoroborate;1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate >
CBNumber
CB8452526
Molecular Formula
C8H10BF4N3
Formula Weight
234.99
MOL File
59016-56-7.mol
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CDAP Property

Melting point:
196-200°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
Powder
color 
White to yellow
biological source
synthetic
Water Solubility 
Soluble in water, and acetonitrile.
λmax
301nm(CH3CN)(lit.)
BRN 
5685616
InChI
InChI=1S/C8H10N3.BF4/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3,4)5/h3-6H,1-2H3;/q+1;-1
InChIKey
MBLVMDCQDCVKNE-UHFFFAOYSA-N
SMILES
[B+3]([F-])([F-])([F-])[F-].N(C1=CC=[N+](C#N)C=C1)(C)C
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-60-36/37-9
RIDADR 
1759
WGK Germany 
3
F 
3-8-10-21
HazardClass 
8
PackingGroup 
III
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
RES1458C
Product name
CDAP
Packaging
100mg
Price
$114
Updated
2025/07/31
Sigma-Aldrich
Product number
SBR00023
Product name
1-Cyano-4-dimethylaminopyridinium tetrafluoroborate Ready Made Solution
Purity
organic cyanylating reagent, 100?mg/mL in acetonitrile
Packaging
1ML
Price
$196
Updated
2025/07/31
Sigma-Aldrich
Product number
RES1458C
Product name
CDAP
Packaging
500mg
Price
$376
Updated
2025/07/31
Sigma-Aldrich
Product number
RES1458C
Product name
CDAP
Packaging
1g
Price
$640
Updated
2025/07/31
Sigma-Aldrich
Product number
C2776
Product name
1-Cyano-4-dimethylaminopyridinium tetrafluoroborate
Purity
organic cyanylating reagent
Packaging
100mg
Price
$174.8
Updated
2025/07/31
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CDAP Chemical Properties,Usage,Production

Chemical Properties

White to yellow powder

Uses

1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.

Biological Activity

CDAP is a cyanylation reagent for protein sulfhydryl groups which is used to prepare protein-polysaccharide conjugates. CDAP is also an activating agent for polysaccharide resins and is used for the conjugation of lipopolysaccharides while retaining their endotoxic activity.

CDAP is considered to be a less toxic reagent as compared to cyanogen bromide (CNBr) (a known polysaccharides activator). In addition, CDAP is easier to use as it can be employed at a lower pH and has fewer side reactions. It is known th at CDAP polysaccharide activation efficiency is optimal at pH 9-10. It was also reported th at direct conjugation of protein to CDAP-activated polysaccharides can be performed under mildly alkaline conditions (pH 7-9). It has also been reported th at proteins could also be conjugated to CDAP-activated polysaccharides at pH 5.

CDAP Preparation Products And Raw materials

Raw materials

Preparation Products

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CDAP Suppliers

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Shanghai Changer Pharmaceutical Technology Co. Ltd.
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View Lastest Price from CDAP manufacturers

Henan Fengda Chemical Co., Ltd
Product
CDAP 59016-56-7
Price
US $6.00-0.20/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
R&D Scientific Inc.
Product
1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate 59016-56-7
Price
US $1600.00/g
Min. Order
1g
Purity
98
Supply Ability
100 Kg
Release date
2024-02-02
Career Henan Chemical Co
Product
CDAP 59016-56-7
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-09

59016-56-7, CDAPRelated Search:

Pyridine-N-oxide 1,1'-DIBENZYL-4,4'-BIPYRIDINIUM DICHLORIDE Cyanamide CDAP 4-Aminopyridine 4-Dimethylaminopyridine Pyridine hydrofluoride N-Methyl-4-pyridinamine Ammonium fluoborate

  • 4-(dimethylamino)pyridin-1-ium-1-carbonitrile
  • N-cyanogen-4-dimethylamino-pyridine tetrafluoroborate
  • N-CYANO-4-DIMETHYLAMINOPYRIDINIUM TETRA FLUOROBORATE
  • 1-CYANO-4-DIMETHYLAMINO-PYRIDINIUM TETRAFLUOROBORATE
  • CDAP
  • CDAP N-Cyano-4-dimethylaminopyridinium tetrafluoroborate
  • 1-Cyano-4-dimethylaminopyridinium tetrafluoroborate,97+%
  • N-Cyano-4-diMethylaMinopyridiniuM tetrafluoroborat
  • 1-Cyano-4-(dimethylamino)pyridin-1-ium tetrafluoroborate
  • 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98% pale yellow solid
  • 4-(DiMethylaMino)pyridin-1-iuM-1-carbonitriletetrafluoroborate
  • 1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate &gt
  • 1-Cyano-4-Dimethylamino pyridinium tetrafluoro boric acid
  • 1-Cyano-4-Dimethylaminopyridinium Tetrafluoroborate (CDAP) extrapure, 97.5%
  • N-Cyano-4-Dimethyl- aminopyridinium Tetrafluoroborate (CDAP)-
  • 1-Cyano-4-dimethylaminopyridinium tetrafluoroborate Ready Made Solution
  • 59016-56-7
  • C8H10N3BF4
  • C8H10BF4N3
  • C-C Bond Formation
  • BioChemical
  • Biochemicals and Reagents
  • Synthetic Reagents
  • Others
  • Derivatization agents
  • Luminescent Compounds/Detection
  • proteinmod