ChemicalBook > CAS DataBase List > Diethyl acetylenedicarboxylate

Diethyl acetylenedicarboxylate

Product Name
Diethyl acetylenedicarboxylate
CAS No.
762-21-0
Chemical Name
Diethyl acetylenedicarboxylate
Synonyms
Diethyl but-2-ynedioate;DIETHYL BUTYNEDIOATE;Diethyl 2-butynedioate;YL2-BUTYNEDIOATE;Diethyl butyrate;Diethyl acetylenedic;diethylbut-2-indioat;Bis(carboethoxy)acetylene;Diethyl but-2-yne-1,4-dioate;Bis-(Ethoxycarbonyl)acetylene
CBNumber
CB8456726
Molecular Formula
C8H10O4
Formula Weight
170.16
MOL File
762-21-0.mol
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Diethyl acetylenedicarboxylate Property

Melting point:
1-3 °C
Boiling point:
107-110 °C11 mm Hg(lit.)
Density 
1.063 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.443(lit.)
Flash point:
202 °F
storage temp. 
2-8°C
form 
Liquid
Specific Gravity
1.063
color 
Clear light yellow
Water Solubility 
Soluble in ethanol, ethyl ether, CCl4, Insoluble in water.
BRN 
743166
CAS DataBase Reference
762-21-0(CAS DataBase Reference)
NIST Chemistry Reference
Diethylacetylene dicarboxylate(762-21-0)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-25
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
F 
8-10
HazardClass 
8
PackingGroup 
III
HS Code 
29171990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
159441
Product name
Diethyl acetylenedicarboxylate
Purity
95%
Packaging
5g
Price
$49.3
Updated
2024/03/01
Sigma-Aldrich
Product number
159441
Product name
Diethyl acetylenedicarboxylate
Purity
95%
Packaging
25g
Price
$151
Updated
2024/03/01
TCI Chemical
Product number
A0089
Product name
Diethyl Acetylenedicarboxylate
Purity
>96.0%(GC)
Packaging
25mL
Price
$98
Updated
2024/03/01
TCI Chemical
Product number
A0089
Product name
Diethyl Acetylenedicarboxylate
Purity
>96.0%(GC)
Packaging
250mL
Price
$734
Updated
2024/03/01
Alfa Aesar
Product number
A11719
Product name
Diethyl acetylenedicarboxylate, 96%
Packaging
25g
Price
$66.65
Updated
2024/03/01
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Diethyl acetylenedicarboxylate Chemical Properties,Usage,Production

Chemical Properties

Diethyl acetylenedicarboxylate is a clear light yellow liquid which has a disagreeable smell. It is a cheap and readily available material in industry. The triple bond is a critical and useful functional group, and it has extensive applications in organic synthesis. It can react with amines, aldehydes, ketones, etc. Therefore it can be used to form various heterocycles.

Synthesis of diethyl acetylenedicarboxylate

Uses

Diethyl acetylenedicarboxylate is used as a protein cross-linker. It is also used in the synthesis of 3,4,5-trisubstituted 2(5H)-furanone derivatives, highly functionalized thiazolidinone derivatives, novel cyclic peroxide glucosides and 4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction.

Uses

Diethyl acetylenedicarboxylate was used in the synthesis of:

  • 3,4,5-trisubstituted 2(5H)-furanone derivatives
  • highly functionalized thiazolidinone derivatives
  • novel cyclic peroxide glucosides
  • 4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction

General Description

Diethyl acetylenedicarboxylate is a protein cross-linker.

Purification Methods

Dissolve the ester in *C6H6, wash it with NaHCO3, H2O, dry over Na2SO4, filter, evaporate and distil it in a vacuum [IR: Walton & Hughes J Am Chem Soc 79 3985 1957, Truce & Kruse J Am Chem Soc 81 5372 1959]. [Beilstein 2 H 803.]

Diethyl acetylenedicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethyl acetylenedicarboxylate Suppliers

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View Lastest Price from Diethyl acetylenedicarboxylate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Diethyl acetylenedicarboxylate 762-21-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-20
Hebei Mujin Biotechnology Co.,Ltd
Product
Diethyl acetylenedicarboxylate 762-21-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-01
Hebei Kingfiner Technology Development Co.Ltd
Product
Diethyl acetylenedicarboxylate 762-21-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-06-18

762-21-0, Diethyl acetylenedicarboxylateRelated Search:

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