ChemicalBook > CAS DataBase List > TAUROURSODEOXYCHOLIC ACID SODIUM SALT

TAUROURSODEOXYCHOLIC ACID SODIUM SALT

Product Name: TAUROURSODEOXYCHOLIC ACID SODIUM SALT
CAS No.: 35807-85-3
Chemical Name: TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Synonyms: TUDC;auroursodeoxycholate Sodium;SODIUM TAUROURSODEOXYCHOLATE;Ursodeoxycholyltaurine sodium;Tauroursodeoxycholate (Sodium);Urosodeoxycholic Acid Impurity 25;Taurocursodeoxycholic acid sodium;Sodium Tauroursodeoxycholate (TUDC);Sodium tauroursodesoxycholate, >=97%;TAUROURSODEOXYCHOLIC ACID SODIUM SALT
CBNumber: CB8459121
Molecular Formula: C26H46NNaO6S
Formula Weight: 523.7
MOL File: 35807-85-3.mol

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TAUROURSODEOXYCHOLIC ACID SODIUM SALT Property

Melting point:: 173-175°C
alpha: +40～+50°(D/20℃)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly, Heated), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form: Solid
color: Off-White to Pale Beige
Water Solubility: water: 100mg/mL
InChIKey: WSSCRQYICWZEFG-SXXADWEANA-N
SMILES: C[C@]12CC[C@]3([H])[C@]4(CC[C@@H](O)C[C@@]4([H])C[C@H](O)[C@@]3([H])[C@]1([H])CC[C@]2([H])[C@H](C)CCC(=O)NCCS(O)(=O)=O)C.[NaH] |&1:1,4,6,9,12,15,17,19,23,25,r|

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Safety

WGK Germany: 2
RTECS: KI7372500
HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P313Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T0266
Product name: Sodium tauroursodeoxycholate
Packaging: 500mg
Price: $587
Updated: 2025/07/31

Sigma-Aldrich

Product number: T0266
Product name: Sodium tauroursodeoxycholate
Packaging: 1g
Price: $945
Updated: 2025/07/31

Sigma-Aldrich

Product number: 580549
Product name: Tauroursodeoxycholic Acid, Sodium Salt
Purity: Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.
Packaging: 1 g
Price: $226
Updated: 2025/07/31

Sigma-Aldrich

Product number: 580549
Product name: Tauroursodeoxycholic Acid, Sodium Salt
Purity: Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.
Packaging: 5 g
Price: $768
Updated: 2025/07/31

Cayman Chemical

Product number: 9003379
Product name: Tauroursodeoxycholic Acid (sodium salt)
Packaging: 1mg
Price: $25
Updated: 2021/12/16

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TAUROURSODEOXYCHOLIC ACID SODIUM SALT Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Tauroursodeoxycholic Acid Sodium Salt is a bile related salt for isolation of lipids and membrane-bound proteins. It is a sodium salt form of Tauroursodeoxycholic Acid which can be used in biological study of inhibition of alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption by glycyrrhizin and glycyrrhetinic acid.

Uses

Sodium tauroursodeoxycholate has been used in a study to assess whether ER stress is involved in palmitic acid upregulation (PA). It has also been used in a study to investigate its effect on Estradiol-17β-D-glucuronide (E-17G) induced cholestasis in female rats.

Uses

Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.

General Description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

in vivo

The effects of Tauroursodeoxycholate (TUDCA) on proliferation and apoptosis of VSMCs in vivo are examined using immunohistochemistry. Tauroursodeoxycholate (10, 50, and 100 mg/kg) increases the caspase 3 activity of injured tissues in a dose-dependent manner, indicating that Tauroursodeoxycholate induces apoptosis of VSMCs in the neointima. Using the injured tissues, further examination and comparison of the phosphorylation level of ERK and MMP-9 expression is performed at 1 week after injury, compared with normal controls. Balloon injury increased both the phosphorylation of ERK and expression of MMP-9 in the tissues. Tauroursodeoxycholate (10, 50, and 100 mg/kg) inhibits phosphorylation of ERK and MMP-9 expression in a dose-dependent manner^[1]. Tauroursodeoxycholate (TUDCA) is a hydrophilic bile acid. Tauroursodeoxycholate as a cytoprotective agent improves liver function and can prevent hepatocellular carcinoma by reducing ER stress and apoptosis. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3, caspase-12, C/EBP homologous protein, c-Jun N-terminal kinase (JNK), activating transcription factor 4 (ATF4), X-box binding protein (XBP), and eukaryotic initiation factor 2α (eIF2α) in Ang II induced ApoE^-/- mice (p<0.05). Tauroursodeoxycholate reduces Angiotensin (Ang) II induced abdominal aortic aneurysm (AAA)? formation in ApoE^-/- mice. Tauroursodeoxycholate is used at a dose of 0.5 g/kg/day in treating Ang II induced ApoE^-/- mice (ER stress inhibitor group). Systolic blood pressure (141.3±5.6 mmHg vs 145.9±8.9 mmHg; p>0.05) and total cholesterol levels (663.6±88.7 mg/dL vs 655.7±65.4 mg/dL; p>0 .05) do not differ between the AAA model group and Tauroursodeoxycholate group. In addition, maximum aortic diameter is significantly smaller in those in Tauroursodeoxycholate group compared with those in the AAA model group (0.95±0.03 mm vs 1.79±0.04 mm; p<0.05). AAA lesion areas are also smaller in those in Tauroursodeoxycholate group than in those in the AAA model group (0.37±0.03 mm² vs 1.51±0.06 mm²; p<0.05)^[2].

IC 50

ERK; Caspase-3; Caspase-12; Human Endogenous Metabolite

TAUROURSODEOXYCHOLIC ACID SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from TAUROURSODEOXYCHOLIC ACID SODIUM SALT manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: TAUROURSODEOXYCHOLIC ACID SODIUM SALT 35807-85-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 2000KGS
Release date: 2025-10-24

Anhuyan (Hainan) Biotechnology Co., LTD

Product: TAUROURSODEOXYCHOLIC ACID SODIUM SALT 35807-85-3
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99
Supply Ability: 100000
Release date: 2025-06-05

Shaanxi Xianhe Biotech Co., Ltd

Product: Sodium tauroursodeoxycholate 35807-85-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 1000KG
Release date: 2025-04-21

35807-85-3, TAUROURSODEOXYCHOLIC ACID SODIUM SALTRelated Search:

Tauroursodeoxycholic acid TAUROLITHOCHOLIC ACID SODIUM SALT Taurodeoxycholic acid sodium salt TAUROHYODEOXYCHOLIC ACID SODIUM SALT Sodium taurocholate β-D-Glucopyranosiduronic acid, (3α,5β,7β)-7-hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl, dipotassium salt (9CI) BHTRKEVKTKCXOH-UYRINQEQSA-N β-D-Glucopyranosiduronic acid, (3α,5β,7α)-7-hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl, dipotassium salt (9CI) Taurochenodeoxycholic acid TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Sodium cholate Ursodeoxycholic acid 5BETA-CHOLANIC ACID

3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT

5-BETA-CHOLANIC ACID-3-ALPHA, 7-BETA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT

5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE-3ALPHA,7BETA-DIOL SODIUM SALT

SODIUM TAUROURSODEOXYCHOLATE

TAURO-URSODEOXYCHOLIC ACID, MONOSODIUM SALT

TAUROURSODEOXYCHOLIC ACID SODIUM SALT

Sodium tauroursodesoxycholate, >=97%

2-(3α,7β-Dihydroxy-24-oxo-5β-cholan-24-yl)amino-1-ethanesulfonic acid sodium salt

2-[(3α,7β-Dihydroxy-24-oxo-5β-cholane-24-yl)amino]-1-ethanesulfonic acid sodium salt

2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid sodium salt

Tauroursodeoxycholic Acid SodiuM Salt (90%)

sodium,2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate

Tauroursodeoxycholate (Sodium)

Sodium Tauroursodeoxycholate (TUDC)

TUDC

Ethanesulfonic acid,2-[[(3a,5b,7b)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

TAUROURSODEOXYCHOLIC ACID SODIUM SALTr

auroursodeoxycholate Sodium

Sodium Tauroursodeoxycholate Sodium Salt

TAUROURSODEOXYCHOLIC ACID SODIUM SALT CAS: 35807-85-3

Sodium Tauroursodeoxycholate (TUDCA Sodium) extrapure, 98%

Ursodeoxycholyltaurine sodium

Urosodeoxycholic Acid Impurity 25

Sodium 2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate

Taurocursodeoxycholic acid sodium

Tauroursodeoxycholate sodium, 10 mM in DMSO

35807-85-3

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35807-85-3