BI8622

Product Name: BI8622
CAS No.: 1875036-74-0
Chemical Name: BI8622
Synonyms: BI8622;BI8622 (BI-8622;4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-
CBNumber: CB84667638
Molecular Formula: C25H26N6O
Formula Weight: 426.51
MOL File: 1875036-74-0.mol

More

Less

BI8622 Property

Boiling point:: 632.6±55.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (293.08 mM; Need ultrasonic)
form: Solid
pka: 11.59±0.70(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

More

Less

BI8622 Chemical Properties,Usage,Production

Biological Activity

BI8622 is a selective HUWE1 (HECTH9; MULE; ARF-BP1) inhibitor (IC50 = 3.2 μM by HUWE1 HECT-domain auto-ubiquitination assay; IC50 >50 μM against other HECT-domain Ub ligases tested). BI8622 inhibits the degradation of HUWE1 target proteiins, including MCL1 (IC50 = 6.8 μM; UV irradiated HeLa MCL1 transfectants), MIZ1 (10 μM; Ls174T), and TopBP1. BI8622 suppresses Ls174T colony formation (IC50 = 8.4 μM in 5 days) and the growth of three colon carcinoma cell lines (20 μM for 5 days; HCT116, HT29, SW480).

BI8622 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BI8622 Suppliers

China 10 United States 5 Global 15

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Country: China
ProdList: 4997
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12000
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

1875036-74-0, BI8622Related Search:

BI8622

BI8622 (BI-8622

4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-

1875036-74-0