BI8622

Product Name: BI8622
CAS No.: 1875036-74-0
Chemical Name: BI8622
Synonyms: BI8622;BI8622 (BI-8622;4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-
CBNumber: CB84667638
Molecular Formula: C25H26N6O
Formula Weight: 426.51
MOL File: 1875036-74-0.mol

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BI8622 Property

Boiling point:: 632.6±55.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (293.08 mM; Need ultrasonic)
form: Solid
pka: 11.59±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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BI8622 Chemical Properties,Usage,Production

Biological Activity

BI8622 is a selective HUWE1 (HECTH9; MULE; ARF-BP1) inhibitor (IC50 = 3.2 μM by HUWE1 HECT-domain auto-ubiquitination assay; IC50 >50 μM against other HECT-domain Ub ligases tested). BI8622 inhibits the degradation of HUWE1 target proteiins, including MCL1 (IC50 = 6.8 μM; UV irradiated HeLa MCL1 transfectants), MIZ1 (10 μM; Ls174T), and TopBP1. BI8622 suppresses Ls174T colony formation (IC50 = 8.4 μM in 5 days) and the growth of three colon carcinoma cell lines (20 μM for 5 days; HCT116, HT29, SW480).

BI8622 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI8622 Suppliers

China 10 United States 5 Global 15

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
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HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
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Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

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Email: vip@med-life.cn
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Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
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RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

1875036-74-0, BI8622Related Search:

BI8622

BI8622 (BI-8622

4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-

1875036-74-0