ChemicalBook > CAS DataBase List > MRT 68921 dihydrochloride
MRT 68921 dihydrochloride
- Product Name
- MRT 68921 dihydrochloride
- CAS No.
- 2080306-21-2
- Chemical Name
- MRT 68921 dihydrochloride
- Synonyms
- MRT 68921 dihydrochloride;MRT 68921 HYDROCHLORIDE;MRT68921 HYDROCHLORIDE;inhibit,MRT 68921,ULK,MRT-68921 dihydrochloride,Inhibitor,MRT68921,Unc-51 like kinase,MRT68921 dihydrochloride,MRT-68921;N-[3-({5-cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)amino]pyrimidin-4-yl}amino)propyl]cyclobutanecarboxamide dihydrochloride
- CBNumber
- CB84673507
- Molecular Formula
- C25H35ClN6O
- Formula Weight
- 471.05
- MOL File
- 2080306-21-2.mol
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MRT 68921 dihydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in H2O:33.3(Max Conc. mg/mL);65.6(Max Conc. mM)
- form
- Solid
- color
- White to off-white
- Water Solubility
- Soluble to 100 mM in water
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N-Bromosuccinimide Price
Tocris
- Product number
- 5780
- Product name
- MRT68921dihydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 25
- Price
- $402
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FM172881
- Product name
- MRT 68921 dihydrochloride
- Packaging
- 25mg
- Price
- $800
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FM172881
- Product name
- MRT 68921 dihydrochloride
- Packaging
- 50mg
- Price
- $1400
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FM172881
- Product name
- MRT 68921 dihydrochloride
- Packaging
- 10mg
- Price
- $400
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC23194
- Product name
- MRT-68921hydrochloride
- Purity
- >98%
- Packaging
- 1g
- Price
- $1450
- Updated
- 2021/12/16
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MRT 68921 dihydrochloride Chemical Properties,Usage,Production
Description
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).
Uses
MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively[1].
target
MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
storage
Desiccate at RT
References
[1] Petherick KJ, et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83. DOI:10.1074/jbc.C114.627778
MRT 68921 dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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MRT 68921 dihydrochloride Suppliers
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