Apigenin 7-glucoside

Product Name: Apigenin 7-glucoside
CAS No.: 578-74-5
Chemical Name: Apigenin 7-glucoside
Synonyms: COSMOSIIN;APIGETRIN;APIGENIN-7-O-GLUCOSIDE;COSMETIN;APIGENIN-7-GLUCOSIDE;Apigenin-7-O-β-D-glucoside;Apigenin-7-O-β-D-glucopyranoside;Apigenin-7-O-β-D-glucopyranoside;apigenin 7-O-β-D-glucoside;Cosmosioside
CBNumber: CB8468248
Molecular Formula: C21H20O10
Formula Weight: 432.38
MOL File: 578-74-5.mol

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Apigenin 7-glucoside Property

Melting point:: 230-237°C
Boiling point:: 788.9±60.0 °C(Predicted)
Density: 1.642±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO (Slightly, Sonicated), Methanol (Slightly)
pka: 6.13±0.40(Predicted)
color: Pale Yellow to Yellow
BRN: 65669
Stability:: Hygroscopic
InChIKey: KMOUJOKENFFTPU-YUVSVTSJNA-N
SMILES: C1(C2=CC=C(O)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:17,20,22,24,r|
LogP: -0.040 (est)
CAS DataBase Reference: 578-74-5(CAS DataBase Reference)

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Safety

Safety Statements: 34/35
WGK Germany: 3
F: 3-10
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 44692
Product name: Apigenin 7-glucoside
Purity: analytical standard
Packaging: 5mg
Price: $235
Updated: 2024/03/01

Sigma-Aldrich

Product number: 44692
Product name: Apigenin 7-glucoside
Purity: analytical standard
Packaging: 25mg
Price: $737.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 00720585
Product name: Apigenin 7-glucoside
Purity: primary pharmaceutical reference standard
Packaging: 10mg
Price: $722
Updated: 2024/03/01

Cayman Chemical

Product number: 26813
Product name: Apigenin 7-glucoside
Packaging: 10mg
Price: $108
Updated: 2024/03/01

Cayman Chemical

Product number: 26813
Product name: Apigenin 7-glucoside
Packaging: 50mg
Price: $422
Updated: 2024/03/01

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Apigenin 7-glucoside Chemical Properties,Usage,Production

Uses

Apigenin 7-Glucoside is a by-product during the synthesis of Isorhoifolin (I819700), a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects.

Definition

ChEBI: A glycosyloxyflavone that is apigenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.

Application

Apigenin 7-glucoside is a flavonoid with anti-inflammatory and anxiolytic activities. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells when used at concentrations ranging from 0.16 to 10 μM. In vivo, apigenin 7-glucoside (10 mg/kg) reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury. It also increases the number of entries and the time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic activity.

Biological Functions

Apigenin 7-glucoside inhibited HL-60 cell growth, dose- and time-dependently, but did not cause apoptosis. The distribution of cells at different stages in the cell cycle indicated an accumulation of treated cells in the G2/M phase. Moreover, apigenin 7-glucoside induced granulocytic differentiation of HL-60 cells[1].

References

[1] Eri Nakazaki. “Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells.” European Journal of Nutrition 52 1 (2013): 25–35.

Apigenin 7-glucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Apigenin 7-glucoside Suppliers

China 208 France 2 Germany 6 India 4 Japan 1 Switzerland 1 United Kingdom 10 United States 27 Global 259

Shanghai Zhiyun Biotechnology Co., Ltd

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BioBioPha Co., Ltd.

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View Lastest Price from Apigenin 7-glucoside manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Apigenin 7-glucoside 578-74-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-09-07

Bonerge(Hunan) Lifescience Co., Ltd.

Product: Apigenin 7-glucoside 578-74-5
Price: US $0.00/kg
Min. Order: 25kg
Purity: 99%
Supply Ability: 8 tons
Release date: 2023-06-02

Shanghai Standard Technology Co., Ltd.

Product: Apigenin 7-glucoside 578-74-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-22

578-74-5, Apigenin 7-glucosideRelated Search:

APIGENIN-7-GLUCURONIDE Apigenin 7-O-(2G-rhaMnosyl)gentiobioside APIIN Apigenin 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL AMYLOGLUCOSIDASE CHLOROPHOSPHONAZO III Polydextrose L-Aspartic acid L-Theanine Hematoxylin evocarpine Sodium ferulic Oxalic acid apigenin 7-O-(6-O-malonylglucoside) 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone 6-beta-D-Glucopyranosyl-8-beta-D-xylopyranosylapigenin Apigenin 6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside

COSMETIN

4H-1-Benzopyran-4-one,7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)

Apigenin 7-beta-D-glucoside

Apigenin 7-glucoside SynonyMs:Apigetrin

Apigenin 7-b-D-glucoside

4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-

Apigenin 7-glucoside, >=98%

Apigetrin(Apigenin-7-O-glucoside)

5-Hydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

Apigenin 7-glucoside, 98%, from Dendranthema indicum (L.) Des Moul.

5-hydroxy-2-(4-hydroxyphenyl)-7-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-4-one

Apigenin 7-glucoside, BR

Apigenin, 7-β-D-glucopyranoside

COSMIIN

COSMOSIIN

APIGENIN-7-O-GLUCOSIDE

APIGENIN-7-GLUCOSIDE

APIGETRIN

7-O-BETA-D-GLUCOPYRANOSYLOXY-4',5-DIHYDROXYFLAVONE

7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 7- (.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4- hydroxyphenyl)-

APIGENIN-7-O-GLUCOSIDE WITH HPLC

Apigetrin, Cosmosiin

Apigenin 7-β-D-glucoside

Cosmosioside

4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- (9ci)

7-o-(beta-D-Glucosyl)apigenin

Apigenin, 7-beta-D-glucopyranoside

Cosemetin

APIGENIN-7-GLUCOSIDE (COSMOSIIN)(P)

APIGENIN-7-O-GLUCOSIDE hplc

Apigenin-7-O-β-D-glucopyranoside

APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(P)

APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(SH)

Apigenin-7-O-β-D-glucoside

Apigenin 7-glucoside (Apigenin-7-O-β-D-glucopyranoside

Apigenin 7-glucoside CRS

Thalictiin

5-Hydroxy-2-(4-hydroxyphenyl)-7-((2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one

apigenin 7-O-β-D-glucoside

Apigenin 7-O-β-glucoside

Apigenin 7-glucoside USP/EP/BP

5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

Apigetrin (Apigenin-7-O-β-D-glucopyranoside

7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-...

Apigenin-7-O-β-D-glucopyranoside

Cosmoside

578-74-5

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Tri-substituted Flavones