QUINOLINE-6-CARBOHYDRAZIDE

Product Name: QUINOLINE-6-CARBOHYDRAZIDE
CAS No.: 5382-47-8
Chemical Name: QUINOLINE-6-CARBOHYDRAZIDE
Synonyms: 6QuinolCON2;6-quinolinecarbohydrazide;QUINOLINE-6-CARBOHYDRAZIDE;6-Quinolinecarbohydrazide , tech;6-Quinolinecarboxylic acid hydrazide;quinoline-6-carbohydrazide(SALTDATA: FREE)
CBNumber: CB8468839
Molecular Formula: C10H9N3O
Formula Weight: 187.2
MOL File: 5382-47-8.mol

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QUINOLINE-6-CARBOHYDRAZIDE Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: Q990095
Product name: Quinoline-6-carbohydrazide
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 037875
Product name: Quinoline-6-carbohydrazide
Packaging: 500mg
Price: $113
Updated: 2021/12/16

AK Scientific

Product number: Y9387
Product name: Quinoline-6-carbohydrazide
Packaging: 500mg
Price: $202
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0304628
Product name: 6-QUINOLINE CARBOHYDRAZIDE
Purity: 95.00%
Packaging: 5MG
Price: $504.13
Updated: 2021/12/16

ChemBridge Corporation

Product number: BB-3020412
Product name: quinoline-6-carbohydrazide
Purity: 95%
Packaging: 1g
Price: $185
Updated: 2021/12/16

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QUINOLINE-6-CARBOHYDRAZIDE Chemical Properties,Usage,Production

Synthesis

38896-30-9

5382-47-8

General procedure for the synthesis of quinoline-6-carbohydrazide from methyl 6-quinolinecarboxylate: Methyl 6-quinolinecarboxylate (0.10 mol) was dissolved in ethanol (50 mL), 99% hydrazine hydrate (0.10 mol) was added, and the mixture was refluxed for 17 hours. Upon completion of the reaction, the reaction mixture was cooled and the resulting solid was collected by filtration and washed with a small amount of cold methanol to give quinoline-6-carbohydrazide. The reaction process was monitored by thin layer chromatography (TLC) with the unfolding agent being toluene: acetone (8:2, v/v). The product was a colorless solid in 89% yield, melting point 195-197 °C. IR (KBr, cm^-1): 3376, 3291 (NH2), 1689 (C=O, amide).1H NMR (400 MHz, DMSO-d6): δ 10.34 (br s, 1H, NH), 8.89 (dd, J = 1.7, 4.1 Hz, 1H) , 8.38-8.43 (m, 2H), 8.19 (dd, J = 1.6, 8.3 Hz, 1H), 7.97 (d, J = 7.7 Hz, 1H), 7.53 (dd, J = 4.1, 8.3 Hz, 1H), 4.71 (br s, 2H, NH2).

References

[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 5, p. 2017 - 2029
[2] European Journal of Medicinal Chemistry, 2014, vol. 71, p. 24 - 30
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 3, p. 761 - 780
[4] Medicinal Chemistry, 2013, vol. 9, # 4, p. 596 - 607

QUINOLINE-6-CARBOHYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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QUINOLINE-6-CARBOHYDRAZIDE Suppliers

Belgium 1 China 16 India 1 United States 2 Global 20

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Thermo Fisher Scientific

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9ding chemical ( Shanghai) Limited

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Energy Chemical

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Shandong Welt Chem. Co.,Ltd.

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Changzhou Qianai Biotechnology Co., Ltd

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5382-47-8, QUINOLINE-6-CARBOHYDRAZIDERelated Search:

N'-(4-CHLOROBENZOYL)-6-QUINOLINECARBOHYDRAZIDE N-PHENYL-2-(6-QUINOLINYLCARBONYL)-1-HYDRAZINECARBOTHIOAMIDE N-(TERT-BUTYL)-2-(6-QUINOLINYLCARBONYL)-1-HYDRAZINECARBOTHIOAMIDE N-ETHYL-2-(6-QUINOLINYLCARBONYL)-1-HYDRAZINECARBOTHIOAMIDE N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2-(6-QUINOLINYLCARBONYL)-1-HYDRAZINECARBOTHIOAMIDE QUINOLINE-6-CARBOHYDRAZIDE N'-[(Z)-(4-METHYLPHENYL)METHYLIDENE]-6-QUINOLINECARBOHYDRAZIDE N'-(4-METHYLBENZOYL)-6-QUINOLINECARBOHYDRAZIDE N'-[(E)-1H-INDOL-3-YLMETHYLIDENE]-6-QUINOLINECARBOHYDRAZIDE N'-[(E)-2-THIENYLMETHYLIDENE]-6-QUINOLINECARBOHYDRAZIDE

QUINOLINE-6-CARBOHYDRAZIDE

6-quinolinecarbohydrazide

quinoline-6-carbohydrazide(SALTDATA: FREE)

6-Quinolinecarbohydrazide , tech

6QuinolCON2

6-Quinolinecarboxylic acid hydrazide

5382-47-8