ChemicalBook > CAS DataBase List > AZD 3241

AZD 3241

Product Name
AZD 3241
CAS No.
890655-80-8
Chemical Name
AZD 3241
Synonyms
BDBM50;AZD3242;AZD 3241;BCP30847;GTPL10052;TT3345YXVR;Verdiperstat;Verdiperstat [USAN];Verdiperstat (AZD3241);AZD 3241; VERDIPERSTAT
CBNumber
CB84695486
Molecular Formula
C11H15N3O2S
Formula Weight
253.32
MOL File
890655-80-8.mol
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AZD 3241 Property

Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/mL; DMSO: 10 mg/mL; Ethanol: 2 mg/mL
form 
A solid
pka
8.25±0.20(Predicted)
color 
White to light brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0016916
Product name
Verdiperstat
Purity
99.84%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0016916
Product name
Verdiperstat
Purity
99.84%
Packaging
50mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0016916
Product name
Verdiperstat
Purity
99.84%
Packaging
100mg
Price
$700
Updated
2021/12/16
DC Chemicals
Product number
DC12267
Product name
Verdiperstat(AZD3241)
Purity
>98%
Packaging
250mg
Price
$1200
Updated
2021/12/16
DC Chemicals
Product number
DC12267
Product name
Verdiperstat(AZD3241)
Purity
>98%
Packaging
1g
Price
$2500
Updated
2021/12/16
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AZD 3241 Chemical Properties,Usage,Production

Uses

Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.

References

[1] Johnstr?m P, et al. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nucl Med Biol. 2015 Jun;42(6):555-60. DOI:10.1016/j.nucmedbio.2015.02.001
[2] Jucaite A, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain. 2015 Sep;138(Pt 9):2687-700. DOI:10.1093/brain/awv184

AZD 3241 Preparation Products And Raw materials

Raw materials

Preparation Products

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890655-80-8, AZD 3241Related Search:


  • AZD 3241
  • AZD3241;AZD-3241;AZD 3241
  • Verdiperstat (Synonyms: AZD3241)
  • Verdiperstat
  • AZD 3241; VERDIPERSTAT
  • 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo-
  • AZD3242
  • Verdiperstat (AZD3241)
  • inhibit,Glutathione Peroxidase,Verdiperstat,Inhibitor,AZD-3241
  • 1-(2-Isopropoxyethyl)-2-thioxo-1,2,3,5-tetrahydro-pyrrolo[3,2-d]pyrimidin-4-one
  • 1-[2-(propan-2-yloxy)ethyl]-2-sulfanylidene-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
  • 1-{2-[(propan-2-yl)oxy]ethyl}-2-sulfanylidene-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
  • BCP30847
  • BDBM50
  • GTPL10052
  • TT3345YXVR
  • Verdiperstat (USAN/INN)
  • Verdiperstat [USAN]
  • 1-(2-Isopropoxyethyl)-2-thioxo-2,3-dihydro-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
  • Verdiperstat, 10 mM in DMSO
  • 890655-80-8