CYLD ANTIBODY
Source Reactivity Background References- Product Name
- CYLD ANTIBODY
- Chemical Name
- CYLD ANTIBODY
- Synonyms
- CYLD ANTIBODY
- CBNumber
- CB84724775
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb5784
- Product name
- CYLD antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
CYLD ANTIBODY Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Monkey
Background
CYLD is a cytoplasmic deubiquitinating enzyme encoded by a tumor suppressor gene altered in individuals diagnosed with cylindromatosis, a genetic condition characterized by benign tumors of skin appendages. Functional CYLD deubiquitinase regulates inflammation and cell proliferation by down regulating NF-κB signaling through removal of ubiquitin chains from several NF-κB pathway proteins. CYLD is a negative regulator of proximal events in Wnt/β-catenin signaling and is a critical regulator of natural killer T cell development. The transcription factor Snail can inhibit CYLD expression, resulting in melanoma cell proliferation.
References
[1] Biggs, P.J. et al. (1995) Nat Genet 11, 441-3.
[2] Sun, S.C. (2010) Cell Death Differ 17, 25-34.
[3] Regamey, A. et al. (2003) J Exp Med 198, 1959-64.
[4] Glittenberg, M. and Ligoxygakis, P. (2007) Fly (Austin) 1, 330-2.
[5] Tauriello, D.V. et al. (2010) Mol Cell 37, 607-19.
[6] Lee, A.J. et al. (2010) EMBO J 29, 1600-12.
[7] Massoumi, R. et al. (2009) J Exp Med 206, 221-32.
CYLD ANTIBODY Preparation Products And Raw materials
Raw materials
Preparation Products
CYLD ANTIBODY Suppliers
- Tel
- 18007124176 19384116026
- 2706668885@qq.com
- Country
- China
- ProdList
- 4987
- Advantage
- 58
- Tel
- 027-87196173
- cusabio@163.com
- Country
- China
- ProdList
- 6066
- Advantage
- 58
- Tel
- 0755-26755892 1-949-553-1900
- international@genetex.com
- Country
- China
- ProdList
- 6092
- Advantage
- 58
- Tel
- 858.663.9055 8586639055
- NSJBioname@qq.com
- Country
- China
- ProdList
- 6941
- Advantage
- 58
- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
- 58
- Tel
- 18886812933
- sales@biosynth.com
- Country
- China
- ProdList
- 6218
- Advantage
- 58
- Tel
- 21-80243558 86218024
- info@cellsignal.cn
- Country
- China
- ProdList
- 6725
- Advantage
- 58
- Tel
- 4006-123-828 13162017139
- market@ab-mart.com
- Country
- China
- ProdList
- 6917
- Advantage
- 58
- Tel
- 13047170542
- marketing@fn-test.com
- Country
- China
- ProdList
- 6600
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58