ChemicalBook > CAS DataBase List > 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

Product Name
2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
CAS No.
175135-47-4
Chemical Name
2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
Synonyms
O4I1;O411;OSI1;OSI 1;OSI1;OSI 1;O4I1, >98%;O4I1, 10 mM in DMSO;4-(4-METHOXYBENZYLOXY)PHENYLACETONITRILE;2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE;4-[(4-Methoxyphenyl)methoxy]benzeneacetonitrile
CBNumber
CB8473105
Molecular Formula
C16H15NO2
Formula Weight
253.3
MOL File
175135-47-4.mol
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2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Property

Boiling point:
424.5±30.0 °C(Predicted)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly
form 
A crystalline solid
color 
Light yellow to yellow
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P222Do not allow contact with air.

P231Handle under inert gas.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P422Store contents under …

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0625
Product name
O4I1
Packaging
100MG
Price
$119
Updated
2025/07/31
Cayman Chemical
Product number
19935
Product name
O4I1
Purity
≥98%
Packaging
5mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
19935
Product name
O4I1
Purity
≥98%
Packaging
10mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
19935
Product name
O4I1
Purity
≥98%
Packaging
25mg
Price
$172
Updated
2024/03/01
Cayman Chemical
Product number
19935
Product name
O4I1
Purity
≥98%
Packaging
50mg
Price
$292
Updated
2024/03/01
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2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Chemical Properties,Usage,Production

Description

O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.

Uses

O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.

References

[1] XINLAI CHENG. Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and Derivatives as Potent Oct3/4 Inducers[J]. Journal of Medicinal Chemistry, 2015, 58 12: 4976-4983. DOI: 10.1021/acs.jmedchem.5b00144

2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Suppliers

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175135-47-4, 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILERelated Search:

{4-[(3-methoxybenzyl)oxy]phenyl}acetonitrile 4-ETHOXYPHENYLACETONITRILE 4-Benzyloxyphenylacetonitrile 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE 4-Methoxybenzyl cyanide 4-Hydroxybenzyl cyanide

  • 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
  • O411
  • O4I1
  • 4-(4-METHOXYBENZYLOXY)PHENYLACETONITRILE
  • 4-[(4-Methoxyphenyl)methoxy]benzeneacetonitrile
  • 2-[4-[(4-methoxyphenyl)methoxy]phenyl]acetonitrile
  • O4I1, >98%
  • OSI 1
  • OSI1
  • OSI1;OSI 1
  • Benzeneacetonitrile, 4-[(4-methoxyphenyl)methoxy]-
  • O4I1, 10 mM in DMSO
  • 175135-47-4
  • Inhibitors