APOLIPOPROTEIN A-I, HUMAN

Product Name
APOLIPOPROTEIN A-I, HUMAN
Chemical Name
APOLIPOPROTEIN A-I, HUMAN
Synonyms
APO A-1;C117399;APO A-I;MGC117399;HUMAN APOA-I;APO-A1, HUMAN;APO A-I, HUMAN;ApoA-1 from rat;APOLIPROTEIN A-I;APOLIPOPROTEIN AI
CBNumber
CB8474566
Formula Weight
0
MOL File
Mol file
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APOLIPOPROTEIN A-I, HUMAN Property

storage temp. 
−20°C
solubility 
H2O: 1 mg/mL, clear, colorless
form 
solution (clear)
color 
colorless
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Safety

Hazard Codes 
B
Safety Statements 
23-24/25
WGK Germany 
3
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB2502171
Product name
Anti-APOA1 antibody produced in goat
Purity
affinity isolated antibody, buffered aqueous solution
Packaging
100μG
Price
$568
Updated
2024/03/01
Sigma-Aldrich
Product number
178452
Product name
Apolipoprotein A-I, Human Plasma, High-Density Lipoprotein
Purity
Native apolipoprotein A-I from human plasma. Functions as a cofactor for lecithin-cholesterol acyltransferase. A component of high density lipoprotein.
Packaging
500μg
Price
$247
Updated
2024/03/01
Sigma-Aldrich
Product number
SRP4693
Product name
Apolipoprotein A−I human
Purity
recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
Packaging
100μG
Price
$345
Updated
2023/06/20
Usbiological
Product number
A2299-10F
Product name
Apolipoprotein A-I, Human
Packaging
500ug
Price
$375
Updated
2021/12/16
Usbiological
Product number
139298
Product name
Apolipoprotein AI
Packaging
200ul
Price
$438
Updated
2021/12/16
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APOLIPOPROTEIN A-I, HUMAN Chemical Properties,Usage,Production

Uses

Apolipoprotein A-I human has been used in the cholesterol efflux assay.

General Description

ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.

Biochem/physiol Actions

ApoA-I (apolipoprotein A-I), which is found exclusively in HDL (high-density lipoprotein), has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is thought to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Changes in the level of serum apoA-I may serve as a prognostic marker for non-metastatic nasopharyngeal carcinoma. Low levels of apoA-I in the plasma is linked to hyperhomocysteinemia.

APOLIPOPROTEIN A-I, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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APOLIPOPROTEIN A-I, HUMAN Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai Sig Biotechnology Co., LTD
Tel
021-57810052 18930344717
Fax
021-57810052
Email
2089316240@qq.com
Country
China
ProdList
9395
Advantage
58
Wuhan Chemstan Biotechnology Co., Ltd.
Tel
027-65317797 15926423062
Fax
QQ:422450190
Email
422450190@qq.com
Country
China
ProdList
10408
Advantage
58
Shanghai Yaji Biological Technology Co., Ltd.
Tel
021-34661275 15301693058
Email
yajikit@163.com
Country
China
ProdList
9670
Advantage
58
Shanghai Huzhen Industrial Co., LTD
Tel
021-60345367 13916550749
Email
sales@shzbio.com
Country
China
ProdList
9966
Advantage
58
ACROBiosystems
Tel
18514007688
Email
jiaxin.zhao@acrobiosystems.com
Country
China
ProdList
1183
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58

APOLIPOPROTEIN A-I, HUMANRelated Search:


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  • Application CRMs
  • Certified Reference Materials (CRMs)
  • Clinical Chemistry CRMAlphabetic
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