ANTI-E2F-4

Product Name
ANTI-E2F-4
Chemical Name
ANTI-E2F-4
Synonyms
E2F-4;ANTI-E2F-4;ANTI-E2F4 MOUSE;ANTI-E2F4 (AB-2), HUMAN;ANTI-E2F4 (AB-1), HUMAN;p107/p130-binding protein;ANTI-E2F4 (AB-2) MOUSE MAB;Anti-E2F4 antibody produced in rabbit;Anti-E2F transcription factor 4, p107/p130-binding;Monoclonal Anti-E2F4 antibody produced in mouse
CBNumber
CB8480884
Formula Weight
0
MOL File
Mol file
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ANTI-E2F-4 Property

storage temp. 
−20°C
form 
buffered aqueous solution
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
WH0001874M1
Product name
Monoclonal Anti-E2F4 antibody produced in mouse
Purity
clone 5B7, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
AV31175
Product name
Anti-E2F4 antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μL
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA054128
Product name
Anti-E2F4 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
25μL
Price
$282
Updated
2023/06/20
Sigma-Aldrich
Product number
HPA054128
Product name
Anti-E2F4 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
100μL
Price
$547
Updated
2023/06/20
Sigma-Aldrich
Product number
SAB1410315
Product name
Anti-E2F4 antibody produced in rabbit
Purity
purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$503
Updated
2023/01/07
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ANTI-E2F-4 Chemical Properties,Usage,Production

Uses

Rabbit Anti-E2F4 antibody can be used for western blot (2.0μg/ml) and IHC (4-8μg/ml) applications.

General Description

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. (provided by RefSeq)

Biochem/physiol Actions

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins. It is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It also plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

ANTI-E2F-4 Preparation Products And Raw materials

Raw materials

Preparation Products

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ANTI-E2F-4 Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91

ANTI-E2F-4Related Search:


  • ANTI-E2F-4
  • ANTI-E2F4 (AB-1), HUMAN
  • ANTI-E2F4 (AB-2), HUMAN
  • ANTI-E2F4 (AB-2) MOUSE MAB
  • ANTI-E2F4 MOUSE
  • Monoclonal Anti-E2F4 antibody produced in mouse
  • Anti-E2F transcription factor 4, p107/p130-binding
  • E2F-4
  • p107/p130-binding protein
  • Anti-E2F4 antibody produced in rabbit
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  • Antibodies to Transcription FactorsAntibodies
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