Telratolimod

Product Name: Telratolimod
CAS No.: 1359993-59-1
Chemical Name: Telratolimod
Synonyms: 3M-052;MEDI9197;Telratolimod;Telratolimod (MEDI 9197);Telratolimod, 10 mM in DMSO;N-[4-(4-amino-2-butyl-imidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide;N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide;Toll-like Receptor (TLR),MEDI-9197,inhibit,Inhibitor,Telratolimod,MEDI 9197;Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-
CBNumber: CB84843940
Molecular Formula: C36H59N5O2
Formula Weight: 593.89
MOL File: 1359993-59-1.mol

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Telratolimod Property

Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: slightly soluble; Ethanol: slightly soluble
form: A crystalline solid
pka: 16.28±0.46(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 50mg
Price: $2100
Updated: 2021/12/16

ChemScene

Product number: CS-0039736
Product name: Telratolimod
Purity: 99.04%
Packaging: 100mg
Price: $3300
Updated: 2021/12/16

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Telratolimod Chemical Properties,Usage,Production

Uses

Telratolimod (MEDI9197) is a potent toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].

in vivo

Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors^[1].

IC 50

TLR7; TLR8

References

[1] Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12. DOI:10.1186/2051-1426-2-12

Telratolimod Preparation Products And Raw materials

Raw materials

Preparation Products

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Telratolimod Suppliers

China 41 India 1 United States 3 Global 45

Shanghai Raise Chemical Technology Co.,Ltd

Tel: 15026594951
Fax: 0556-5030632
Email: rs@raise-chem.com
Country: China
ProdList: 4454
Advantage: 55

Shanghai AECOM Biotechnology Co. , Ltd.

Tel: 021-021-20956531 18116226605
Fax: 021-20956532
Email: sui@neosunpharm.com
Country: China
ProdList: 349
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29760
Advantage: 68

Suzhou Nuobeike Biological Technology Co., Ltd.

Tel: 13962527677
Fax: -
Email: 1551481742@qq.com
Country: China
ProdList: 278
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

1359993-59-1, TelratolimodRelated Search:

Telratolimod

Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-

3M-052

MEDI9197

N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide

Toll-like Receptor (TLR),MEDI-9197,inhibit,Inhibitor,Telratolimod,MEDI 9197

N-[4-(4-amino-2-butyl-imidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide

Telratolimod, 10 mM in DMSO

Telratolimod (MEDI 9197)

1359993-59-1

C36H59N5O2