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Telratolimod

Product Name
Telratolimod
CAS No.
1359993-59-1
Chemical Name
Telratolimod
Synonyms
3M-052;MEDI9197;Telratolimod;Telratolimod (MEDI 9197);Telratolimod, 10 mM in DMSO;N-[4-(4-amino-2-butyl-imidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide;N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide;Toll-like Receptor (TLR),MEDI-9197,inhibit,Inhibitor,Telratolimod,MEDI 9197;Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-
CBNumber
CB84843940
Molecular Formula
C36H59N5O2
Formula Weight
593.89
MOL File
1359993-59-1.mol
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Telratolimod Property

Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: slightly soluble; Ethanol: slightly soluble
form 
A crystalline solid
pka
16.28±0.46(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0039736
Product name
Telratolimod
Purity
99.04%
Packaging
5mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0039736
Product name
Telratolimod
Purity
99.04%
Packaging
10mg
Price
$750
Updated
2021/12/16
ChemScene
Product number
CS-0039736
Product name
Telratolimod
Purity
99.04%
Packaging
25mg
Price
$1500
Updated
2021/12/16
ChemScene
Product number
CS-0039736
Product name
Telratolimod
Purity
99.04%
Packaging
50mg
Price
$2100
Updated
2021/12/16
ChemScene
Product number
CS-0039736
Product name
Telratolimod
Purity
99.04%
Packaging
100mg
Price
$3300
Updated
2021/12/16
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Telratolimod Chemical Properties,Usage,Production

Uses

Telratolimod (MEDI9197) is a potent toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity[1].

in vivo

Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors[1].

IC 50

TLR7; TLR8

References

[1] Zhao BG, et al. Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors. J Immunother Cancer. 2014 May 13;2:12. DOI:10.1186/2051-1426-2-12

Telratolimod Preparation Products And Raw materials

Raw materials

Preparation Products

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Telratolimod Suppliers

China 41 India 1 United States 3 Global 45
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1359993-59-1, TelratolimodRelated Search:


  • Telratolimod
  • Octadecanamide, N-[4-[(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy]butyl]-
  • 3M-052
  • MEDI9197
  • N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide
  • Toll-like Receptor (TLR),MEDI-9197,inhibit,Inhibitor,Telratolimod,MEDI 9197
  • N-[4-(4-amino-2-butyl-imidazo[4,5-c]quinolin-1-yl)oxybutyl]octadecanamide
  • Telratolimod, 10 mM in DMSO
  • Telratolimod (MEDI 9197)
  • 1359993-59-1
  • C36H59N5O2