Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- Product Name
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- CAS No.
- 90965-06-3
- Chemical Name
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- Synonyms
- DIMETHYL (1-DIAZO-2-OXOPROPYL)PHOSPHONATE;Ohira-Bestmann reagent;1-Diazo-1-dimethoxyphosphoryl-propan-2-one;Dimethyl (acetyldiazomethyl)phosphonate;dimethyl 1-(1-diazo-2-oxopropyl)phosphonate;1-Diazoacetonylphosphonic Acid Dimethyl Ester;Dimethyl 1-Diazoacetonylphosphonate;Dimethyl (1-azoacetonyl)phosphonate;diMethyl(1-diazo-2-oxopropyl)phosphanate;Dimethyl (1-Diazo-2-oxopropyl)phosphonat
- CBNumber
- CB8489377
- Molecular Formula
- C5H9N2O4P
- Formula Weight
- 192.11
- MOL File
- 90965-06-3.mol
Dimethyl (1-Diazo-2-oxopropyl)phosphonate Property
- Density
- 1.28
- refractive index
- n20/D1.352-1.354
- Flash point:
- 2℃
- storage temp.
- 2-8°C
- solubility
- Chloroform, Methanol (Slightly)
- form
- Oil
- color
- Pale Yellow to Yellow
- Merck
- 14,1177
- BRN
- 4247670
- Stability:
- Light Sensitive
- InChI
- InChI=1S/C5H9N2O4P/c1-4(8)5(7-6)12(9,10-2)11-3/h1-3H3
- InChIKey
- SQHSJJGGWYIFCD-UHFFFAOYSA-N
- SMILES
- P(=O)(OC)(OC)C(=[N+]=[N-])C(=O)C
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22-36
- Safety Statements
- 16-26-36/37
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 742724
- Product name
- Dimethyl (1-diazo-2-oxopropyl)phosphonate solution
- Purity
- ~10% in acetonitrile (H-NMR), ≥96% (HPLC)
- Packaging
- 10ml
- Price
- $502
- Updated
- 2025/07/31
- Product number
- D3546
- Product name
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- Purity
- >97.0%(HPLC)
- Packaging
- 1g
- Price
- $218
- Updated
- 2025/07/31
- Product number
- D3546
- Product name
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate
- Purity
- >97.0%(HPLC)
- Packaging
- 5g
- Price
- $696
- Updated
- 2025/07/31
- Product number
- D5048
- Product name
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate (10% in Acetonitrile)
- Packaging
- 5g
- Price
- $106
- Updated
- 2025/07/31
- Product number
- D5048
- Product name
- Dimethyl (1-Diazo-2-oxopropyl)phosphonate (10% in Acetonitrile)
- Packaging
- 25g
- Price
- $306
- Updated
- 2025/07/31
Dimethyl (1-Diazo-2-oxopropyl)phosphonate Chemical Properties,Usage,Production
Description
Dimethyl (1-diazido-2-oxopropyl)phosphonate is a liquid-added organophosphorus flame retardant with good solubility with water, common organic solvents, and inorganic salts flame retardants, with excellent flame retardant properties, low price and low additive amount and other advantages.
Chemical Properties
Light yellow liquid
Application
Dimethyl (1-diazo-2-oxopropyl)phosphonate can be used as a reagent for the synthesis of:
Ethynyl compounds (alkynes) from aldehydes.
Isoquinoline and pyridine N-oxides by cyclization with oximes in the presence of Rh catalyst.
Dimethyl(diazomethyl)phosphonate through methanolysis, which is further employed as a reagent in the synthesis of enol ethers or alkynes.
Five-member heterocyclic scaffolds of pyrazoles, triazoles, and oxazoles via cycloaddition reaction and multicomponent reaction.
Uses
Reagent for transformation of aldehydes to terminal alkynes and ketones to methyl enol ethers.
reaction suitability
reaction type: C-C Bond Formation
Synthesis
Dissolve NaH (0.67 g, 60% w/w, 16.75 mmol) in benzene (45 mL) and dry THF (15 mL). Cool the mixture on ice. A solution of dimethyl (2-oxopropyl) phosphonate (15.3 mmol) in dry benzene (15 mL) was added. A white solid was formed. The reaction mixture was stirred at room temperature for 1 hour. To the mixture was added a solution of toluidic acid hydrazide (16.23 mmol) in dry benzene (7.5 mL). The mixture was stirred at room temperature overnight. The mixture was filtered with Hyflo. The mixture was concentrated in a vacuum to give dimethyl (1-diazido-2-oxopropyl)phosphonate.
Dimethyl (1-Diazo-2-oxopropyl)phosphonate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dimethyl (1-Diazo-2-oxopropyl)phosphonate manufacturers
- Product
- (1-DIAZO-2-OXO-PROPYL)-PHOSPHONIC ACID DIMETHYL ESTER 90965-06-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- as customer's need
- Supply Ability
- 1000kg
- Release date
- 2018-12-19