4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid

Product Name: 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
CAS No.: 1537891-69-2
Chemical Name: 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
Synonyms: 4-Methyl-4-(2-pyridinyldithio)pentanoic acid;Pentanoic acid, 4-methyl-4-(2-pyridinyldithio)-
CBNumber: CB84920553
Molecular Formula: C11H15NO2S2
Formula Weight: 257.37
MOL File: 1537891-69-2.mol

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4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Property

Boiling point:: 416.1±41.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
pka: 4.54±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Chemical Properties,Usage,Production

Uses

4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid Suppliers

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1537891-69-2, 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acidRelated Search:

(S)-4-(pyridin-2-yldisulfaneyl)pentanoic acid 5-(pyridin-2-yldisulfanyl)pentanoic acid 4-methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid 250266-79-6

Pentanoic acid, 4-methyl-4-(2-pyridinyldithio)-

4-Methyl-4-(2-pyridinyldithio)pentanoic acid

1537891-69-2