N-NITROSOSARCOSINE Property

Melting point:

66-67°C

Boiling point:

220.6°C (rough estimate)

Density 

1.5267 (rough estimate)

refractive index 

1.4715 (estimate)

storage temp. 

-20°C Freezer

solubility 

DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 5 mg/ml

form 

A solid

pka

3.40±0.10(Predicted)

IARC

2B (Vol. 17, Sup 7) 1987

EPA Substance Registry System

N-Nitrososarcosine (13256-22-9)

Safety

RIDADR 

2811

HazardClass 

6.1(b)

PackingGroup 

III

Hazardous Substances Data

13256-22-9(Hazardous Substances Data)

Toxicity

LD50 ipr-mus: 184 mg/kg CNREA8 35,1981,75

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

N-NITROSOSARCOSINE Chemical Properties,Usage,Production

Chemical Properties

Pale-Yellow Crystalline Solid

Uses

A carcinogenic compound.

Definition

ChEBI: A nitrosamine that is sarcosine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group.

Safety Profile

Confirmed carcinogen with experimental tumorigenic data. Mildly toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.See also N-NITROSO COMPOUNDS.

Carcinogenicity

N-Nitrososarcosine is reasonably anticipated to b e a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.