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N-NITROSO-L-PROLINE

Product Name
N-NITROSO-L-PROLINE
CAS No.
7519-36-0
Chemical Name
N-NITROSO-L-PROLINE
Synonyms
NPRO;no-pro;Nsc109545;nitrosoproline;1-Nitrosoproline;N-NITROSO-PROLINE;1-nitroso-l-proline;N-NITROSO-L-PROLINE;L-Proline, nitroso-;L-Proline, 1-nitroso-
CBNumber
CB9489314
Molecular Formula
C5H8N2O3
Formula Weight
144.13
MOL File
7519-36-0.mol
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N-NITROSO-L-PROLINE Property

Melting point:
108-109°C
Boiling point:
262.71°C (rough estimate)
Density 
1.4054 (rough estimate)
refractive index 
1.4472 (estimate)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pka
3.23±0.20(Predicted)
form 
Solid
color 
Pale Yellow to Brown
IARC
3 (Vol. 17, Sup 7) 1987
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Safety

Toxicity
LD50 ipr-mus: 203 mg/kg JMCMAR 16,583,73
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

H341Suspected of causing genetic defects

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P285In case of inadequate ventilation wear respiratory protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
285292
Product name
N-Nitroso-L-proline
Packaging
5mg
Price
$403
Updated
2021/12/16
TRC
Product number
N545450
Product name
N-Nitroso-L-proline
Packaging
50mg
Price
$685
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0000646
Product name
N-NITROSO-L-PROLINE
Purity
95.00%
Packaging
5MG
Price
$738.1
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
12682
Product name
N-Nitroso-L-proline
Packaging
10mg
Price
$860
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0000646
Product name
N-NITROSO-L-PROLINE
Purity
95.00%
Packaging
100MG
Price
$1593.9
Updated
2021/12/16
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N-NITROSO-L-PROLINE Chemical Properties,Usage,Production

Chemical Properties

Colourless Plates

Uses

A nitrosoamino acid with oncogenicity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg

Uses

A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.

Production Methods

There is no indication that nitrosoproline was made commercially. It has been reported in cured meats (e.g., bacon) at concentrations of 340–440 μg/kg. Both higher and lower levels in several cured products have been reported by several authors.

Definition

ChEBI: N-Nitrosoproline is a L-proline derivative.

Safety Profile

Poison by intraperitoneal route.Questionable carcinogen with experimental tumorigenicdata. Many nitroso compounds are carcinogens. Whenheated to decomposition it emits toxic fumes of NOx. Seealso NITROSO COMPOUNDS.

Carcinogenicity

Mice were given 0.1% NPRO in drinking water for 26 weeks, and no more lung adenomas were seen than in untreated controls at 38 weeks, showing a lack of carcinogenicity. In rats, higher doses (0.145%) in drinking water for 2 years showed no tumors that were not seen in untreated controls (174). IARC classified NPRO as not classifiable as to carcinogenicity to humans (Group 3).

N-NITROSO-L-PROLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-NITROSO-L-PROLINE Suppliers

Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
9122
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988968278
Fax
QQ:3283937693
Email
sales@ubiochem.com
Country
China
ProdList
4297
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
Shanghai Uchem Inc.
Tel
15618758386 15618758386
Fax
QQ:3004479444
Email
sales3@myuchem.com
Country
China
ProdList
2073
Advantage
55
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15494
Advantage
58
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View Lastest Price from N-NITROSO-L-PROLINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N-NITROSO-L-PROLINE 7519-36-0
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-08-15
Career Henan Chemical Co
Product
N-Boc-trans-4-amino-L-proline methyl ester hydrochloride 7519-36-0
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-01-08

7519-36-0, N-NITROSO-L-PROLINERelated Search:


  • 1-Nitrosoproline
  • NPRO
  • L-Proline, 1-nitroso-
  • L-Proline, nitroso-
  • Nsc109545
  • N-NITROSO-L-PROLINE
  • 1-nitroso-l-proline
  • nitrosoproline
  • no-pro
  • N-NITROSO-PROLINE
  • N-Nitroso-L-Proline (Mixture of Isomers)
  • (S)-1-nitrosopyrrolidine-2-carboxylic acid
  • N-NITROSO-L-PROLINE USP/EP/BP
  • N-Nitroso-L-proline D3
  • nitroso - L - proline
  • N-Nitroso-L-proline in methanol
  • 7519-36-0
  • Heterocycles
  • Amino Acids & Derivatives, Heterocycles
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives