TRANS-PERMETHRIN D6 (DIMETHYL D6)
- Product Name
- TRANS-PERMETHRIN D6 (DIMETHYL D6)
- CAS No.
- 82523-59-9
- Chemical Name
- TRANS-PERMETHRIN D6 (DIMETHYL D6)
- Synonyms
- Permethrin D6;TRANS-PERMETHRIN D6 (DIMETHYL D6);trans-Permethrin D6 (dimethyl D6) 100 μg/mL in Acetone;trans-Permethrin D6 ( dimethyl D6), 100 μg /μL in acetone;Permethrin (??????/?????????? mix) (D?, 98%) 100 μg/mL in nonane
- CBNumber
- CB8506023
- Molecular Formula
- C21H14Cl2D6O3
- Formula Weight
- 397.329
- MOL File
- 82523-59-9.mol
N-Bromosuccinimide Price
- Product number
- RDL0013534
- Product name
- TRANS-PERMETHRIN-D6
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.7
- Updated
- 2021/12/16
TRANS-PERMETHRIN D6 (DIMETHYL D6) Chemical Properties,Usage,Production
Uses
Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes)[1][2][3][4][5][6][7].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416. DOI:10.1016/j.fct.2017.11.047
[3] Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933. DOI:10.1371/journal.pntd.0006933
[4] Shelley LK, et al. Immunotoxic and cytotoxic effects of atrazine, permethrin and piperonyl butoxide to rainbow trout following in vitro exposure[J]. Fish Shellfish Immunol. 2012 Aug;33(2):455-8. DOI:10.1016/j.fsi.2012.05.020
[5] Gassner B, et al. The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I[J]. Journal of Pharmacology and Experimental Therapeutics, 1997, 281(2): 855-860. PMID:9152394
[6] Kakko I, et al. The synaptosomal membrane bound ATPase as a target for the neurotoxic effects of pyrethroids, permethrin and cypermethrin[J]. Chemosphere. 2003 May;51(6):475-80. DOI:10.1016/S0045-6535(02)00854-8
[7] Brander SM, et al. The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environ Toxicol Chem. 2012 Dec;31(12):2848-55. DOI:10.1002/etc.2019
[8] Omotoso G, et al. Permethrin exposure affects neurobehavior and cellular characterization in rats' brain. Environ Anal Health Toxicol. 2020 Dec;35(4):e2020022-0. DOI:10.5620/eaht.2020022
TRANS-PERMETHRIN D6 (DIMETHYL D6) Preparation Products And Raw materials
Raw materials
Preparation Products
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