ChemicalBook > CAS DataBase List > GATIFLOXACIN MESYLATE

GATIFLOXACIN MESYLATE

Product Name
GATIFLOXACIN MESYLATE
CAS No.
316819-28-0
Chemical Name
GATIFLOXACIN MESYLATE
Synonyms
AM 1155 mesylate;PD 135432 mesylate);GATIFLOXACIN MESYLATE;BMS 206584-01 mesylate;GATIFLOXACIN MESYLATE USP/EP/BP;Gatifloxacin mesylate (AM 1155 mesylate;AM 1155 MESYLATE;BMS 206584-01 MESYLATE;PD 135432 MESYLATE;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-, MonoMethanesulfonate (9CI)
CBNumber
CB8522263
Molecular Formula
C19H22FN3O4.CH4O3S
Formula Weight
471.503
MOL File
316819-28-0.mol
More
Less

GATIFLOXACIN MESYLATE Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Powder
InChIKey
PMMNVFFMFJMFDB-UHFFFAOYSA-N
SMILES
S(=O)(=O)(O)C.C1(=C(N2CC(C)NCC2)C(OC)=C2N(C3CC3)C=C(C(=O)C2=C1)C(=O)O)F
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ApexBio Technology
Product number
B1216
Product name
Gatifloxacinmesylate
Packaging
1g
Price
$42
Updated
2021/12/16
ChemScene
Product number
CS-1843
Product name
Gatifloxacin(mesylate)
Packaging
500mg
Price
$50
Updated
2021/12/16
ApexBio Technology
Product number
B1216
Product name
Gatifloxacinmesylate
Packaging
5g
Price
$193
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611335
Product name
Gatifloxacin mesylate
Packaging
1g
Price
$397.8
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019501
Product name
GATIFLOXACIN MESYLATE
Purity
95.00%
Packaging
5MG
Price
$503.57
Updated
2021/12/16
More
Less

GATIFLOXACIN MESYLATE Chemical Properties,Usage,Production

Uses

Gatifloxacin mesylate is a fourth generation fluoroquinolone antibiotic with broad-spectrum antibacterial activity. It is able to inhibit bacterial type II topoisomerase (IC50 = 13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA rotamase (IC50 = 0.109 μg/ml). It can be used to treat bacterial conjunctivitis in vivo, and its injection can treat acute urinary tract infections with efficacy comparable to levofloxacin hydrochloride injection[1].

in vivo

Gatifloxacin mesylate (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis[4].

Animal Model:Female BALB/c mice with Nocardia brasiliensis in the right hind footpad.
Dosage:100 mg/kg
Administration:Subcutaneous injection; 3 times a day; 30 days
Result:Reduced the production of lesions in mice.

IC 50

Quinolone; Topoisomerase II: 36.7 μM (IC50)

References

[1] L. DENG. Observation on the curative effect of gatifloxacin mesylate injection in the treatment of acute urinary tract infections[J]. International Medical and Health Herald, 2009. DOI:10.3760/CMA.J.ISSN.1007-1245.2009.05.025.

GATIFLOXACIN MESYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

GATIFLOXACIN MESYLATE Suppliers

China 100 United States 6 Global 106
Jiangxi ravel Biotechnology Co.,Ltd
Tel
400-880-2824 18107960669
Fax
18140514863
Email
79046690@qq.com
Country
China
ProdList
1242
Advantage
58
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2748
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Watson Biotechnology Co.,Ltd
Tel
027-59207879 1972026995 18140587686
Fax
QQ：1972026995
Email
sales@3600chem.com
Country
China
ProdList
4448
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
More
Less

View Lastest Price from GATIFLOXACIN MESYLATE manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.
Product
GATIFLOXACIN MESYLATE 316819-28-0
Price
US $0.00/kg
Min. Order
25kg
Purity
99.0%
Supply Ability
10tons
Release date
2024-04-25
shandong perfect biotechnology co.ltd
Product
Gatifloxacin (mesylate) 316819-28-0
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
100kg
Release date
2023-08-09
Shaanxi Dideu Medichem Co. Ltd
Product
Gatifloxacin mesylate 316819-28-0
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-05-18

316819-28-0, GATIFLOXACIN MESYLATERelated Search:

Maduramycin ammonium Gatifloxacin GATIFLOXACIN MESYLATE

  • AM 1155 mesylate
  • AM 1155 MESYLATE;BMS 206584-01 MESYLATE;PD 135432 MESYLATE
  • BMS 206584-01 mesylate
  • Gatifloxacin mesylate (AM 1155 mesylate
  • PD 135432 mesylate)
  • GATIFLOXACIN MESYLATE
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-, MonoMethanesulfonate (9CI)
  • GATIFLOXACIN MESYLATE USP/EP/BP
  • 316819-28-0
  • 318819-28-0
  • C20H26FN3O7S
  • C19H22FN3O4CH4O3S