MAP1B antibody
Source Reactivity Background References- Product Name
- MAP1B antibody
- Chemical Name
- MAP1B antibody
- Synonyms
- MAP1B antibody
- CBNumber
- CB85652857
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb2882
- Product name
- MAP1B antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $402.9
- Updated
- 2021/12/16
- Product number
- orb2882
- Product name
- MAP1B antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $654.5
- Updated
- 2021/12/16
MAP1B antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat
Background
Microtubule-associated protein 1B is a member of the high molecular weight microtubule binding phosphoprotein family, along with MAP1A. MAP1B is highly expressed in neurons, predominantly during development, where it regulates axonal guidance and elongation through its influence on microtubule dynamics. In mature neurons, MAP1B plays a role in regulation and structure of dendritic spines in glutamatergic synapses. MAP1B deficient neurons have been shown to display structural presynaptic deficiencies, including a decrease in density at synaptic terminals and disruption of synaptic vesicle fusion events. Mutations in MAP1B have been linked to developmental disorders affecting cognitive ability through a deficit in white matter and compromised axons.
References
[1] Gordon-Weeks, P.R. and Fischer, I. (2000) Microsc Res Tech 48, 63-74.
[2] Bodaleo, F.J. et al. (2016) Sci Rep 6, 30069.
[3] Walters, G.B. et al. (2018) Nat Commun 9, 3456.
MAP1B antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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