MIB1 antibody
Source Reactivity Background References- Product Name
- MIB1 antibody
- Chemical Name
- MIB1 antibody
- Synonyms
- MIB1 antibody;Mouse Monoclonal MIB1 Antibody
- CBNumber
- CB85654275
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb157875
- Product name
- Mib1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $402.9
- Updated
- 2021/12/16
- Product number
- orb613754
- Product name
- MIB1 antibody
- Purity
- Antigen affinity chromatography using the immunizing peptide.
- Packaging
- 100μg
- Price
- $499.8
- Updated
- 2021/12/16
- Product number
- orb157875
- Product name
- Mib1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $654.5
- Updated
- 2021/12/16
MIB1 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
Mindbomb homolog 1 is an E3 ligase that facilitates the ubiquitination and the subsequent endocytosis of the Notch ligands, Delta and Jagged. MIB1 appears to promote the ubiquitination and degradation of death-associated protein kinase in vitro. Expression of MIB1 is seen in both adult and embryonic murine tissues. Recently, MIB1 was reported to regulate the extrinsic cell death pathway by binding to cellular FLICE-like inhibitory proteins, which reduces the interaction of caspase-8 with cFLIP and leads to cell death. MIB1 is also involved in T and marginal zone B cell development in the lymphopoietic niches.
References
[1] Koo, B.K. et al. (2005) Development 132, 3459-70.
[2] Matsuda, M. and Chitnis, A.B. (2009) Development 136, 197-206.
[3] Zhang, L. et al. (2007) J Biol Chem 282, 11795-804.
[4] Jin, Y. et al. (2002) J Biol Chem 277, 46980-6.
[5] Zhang, L. and Gallagher, P.J. (2009) Am J Physiol Cell Physiol 297, C1275-83.
[6] Song, R. et al. (2008) J Exp Med 205, 2525-36.
MIB1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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