ChemicalBook > CAS DataBase List > PE 22-28
PE 22-28
- Product Name
- PE 22-28
- Chemical Name
- PE 22-28
- Synonyms
- PE 22-28
- CBNumber
- CB85833715
- Formula Weight
- 0
- MOL File
- Mol file
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PE 22-28 Chemical Properties,Usage,Production
Description
PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin. It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the human channels at 100 nM. It promotes neurogenesis, increasing Psd-95 levels in mouse hippocampi and enhancing synaptogenesis. At 0.3 μg/kg for four days, PE 22-28 improves mouse behavior in tests like the forced swim test, novelty-suppressed feeding, and Porsolt learned helplessness test, suggesting potential for treating depression.
PE 22-28 Preparation Products And Raw materials
Raw materials
Preparation Products
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PE 22-28 Suppliers
- Tel
- 16314854226; +16314854226
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19741
- Advantage
- 58
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View Lastest Price from PE 22-28 manufacturers
Shandong Huizhihan Supply Chain Co., Ltd
- Product
- PE 22-28
- Price
- US $0.00-0.00/BOX
- Min. Order
- 1BOX
- Purity
- 99.99%
- Supply Ability
- 1000
- Release date
- 2024-10-31
zhuzhou dingcheng meihei comestic co.,ltd
- Product
- PE-22-28
- Price
- US $35.00/Box
- Min. Order
- 1Box
- Purity
- 99.99%
- Supply Ability
- 10000000000
- Release date
- 2023-12-22
Hebei Anlijie Biotechnology Co., Ltd
- Product
- PE 22-28
- Price
- US $30.00/mg
- Min. Order
- 100mg
- Purity
- 99%
- Supply Ability
- 80000g
- Release date
- 2023-09-07