ChemicalBook > CAS DataBase List > METFORMIN-D6, HYDROCHLORIDE

METFORMIN-D6, HYDROCHLORIDE

Product Name
METFORMIN-D6, HYDROCHLORIDE
CAS No.
1185166-01-1
Chemical Name
METFORMIN-D6, HYDROCHLORIDE
Synonyms
metformin d6;Diabetosan-d6;Metiguanide-d6;Metformine-D6.HCl;Diabex-d6, Glucophage-d6;Metformin Impurity 9 HCl;METFORMIN-D6, HYDROCHLORIDE;Metformin hydrochloride salt;[2H6]-Metformin hydrochloride;1,1-Dimethyl-d6-biguanide HCl
CBNumber
CB8649272
Molecular Formula
C4H6ClD6N5
Formula Weight
171.661550668
MOL File
Mol file
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METFORMIN-D6, HYDROCHLORIDE Property

Melting point:
215-218°C
storage temp. 
-20°C Freezer
solubility 
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
53183
Product name
Metformin-(dimethyl-d6) hydrochloride
Purity
analytical standard
Packaging
5mg
Price
$648
Updated
2024/03/01
Cayman Chemical
Product number
16921
Product name
Metformin-d6 (hydrochloride)
Purity
≥98% deuterated forms (d1-d6)
Packaging
500μg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
16921
Product name
Metformin-d6 (hydrochloride)
Purity
≥98% deuterated forms (d1-d6)
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
16921
Product name
Metformin-d6 (hydrochloride)
Purity
≥98% deuterated forms (d1-d6)
Packaging
5mg
Price
$469
Updated
2024/03/01
Usbiological
Product number
M3009-75
Product name
Metformin-d6, Hydrochloride
Packaging
1mg
Price
$382
Updated
2021/12/16
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METFORMIN-D6, HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Metformin-d6 is intended for use as an internal standard for the quantification of metformin by GC- or LC-MS. Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day. It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD). Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53-\- human colon cancer mouse xenograft model, but has no effect on HCT116 p53-\- tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I. Formulations containing metformin have been used in the treatment of type 2 diabetes.

Chemical Properties

White Crystalline Solid

Uses

An oral hypoglycemic agent.

METFORMIN-D6, HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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METFORMIN-D6, HYDROCHLORIDE Suppliers

Shandong Huijing bio-pharmaceutical Technology Co. , Ltd.
Tel
15192151674 15192151674
Email
1726957134@qq.com
Country
China
ProdList
213
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
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Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
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sales@chem-strong.com
Country
China
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18042
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Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
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Artis Biotech Co. Ltd.
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0575-18780151478 18582380095
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Shanghai wechem chemical co., ltd
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18824865657
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021-6192 7501
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Shanghai Champ Biopharmaceuticals Co., Ltd.
Tel
021-61537865 13585780846
Email
sales@champchem.com
Country
China
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360
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1185166-01-1, METFORMIN-D6, HYDROCHLORIDERelated Search:


  • Metformin-(dimethyl-d6) hydrochloride
  • Metformine-D6.HCl
  • [2H6]-Metformin hydrochloride
  • 1,1-Di(methyl-d3)biguanide hydrochloride
  • METFORMIN-D6, HYDROCHLORIDE
  • Diabetosan-d6
  • Diabex-d6, Glucophage-d6
  • Metiguanide-d6
  • N,N-Dimethylimidodicarbonimidic Diamide-d6, Hydrochloride
  • 3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine,hydrochloride
  • Metformin-d6 hydrochloride (dimethyl-d6)
  • METFORMIN:HCL (DIMETHYL-D6, 99%)
  • 1,1-Dimethyl-d6-biguanide HCl
  • metformin d6
  • Metformin hydrochloride salt
  • Metformin D6 HydrochlorideQ: What is Metformin D6 Hydrochloride Q: What is the CAS Number of Metformin D6 Hydrochloride Q: What is the storage condition of Metformin D6 Hydrochloride Q: What are the applications of Metformin D6 Hydrochloride
  • Metformin Impurity 9 HCl
  • 1,1-Dimethylbiguanide-d6 hydrochloride
  • N,N-Di(methyl-d3)-imidodicarbonimidic diamide hydrochloride
  • 1185166-01-1
  • 185166-01-1
  • C4H6D6ClN5
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Isotope Labelled Compounds