METFORMIN-D6, HYDROCHLORIDE
- Product Name
- METFORMIN-D6, HYDROCHLORIDE
- CAS No.
- 1185166-01-1
- Chemical Name
- METFORMIN-D6, HYDROCHLORIDE
- Synonyms
- metformin d6;Diabetosan-d6;Metiguanide-d6;Metformine-D6.HCl;Diabex-d6, Glucophage-d6;Metformin Impurity 9 HCl;METFORMIN-D6, HYDROCHLORIDE;Metformin hydrochloride salt;[2H6]-Metformin hydrochloride;1,1-Dimethyl-d6-biguanide HCl
- CBNumber
- CB8649272
- Molecular Formula
- C4H6ClD6N5
- Formula Weight
- 171.661550668
- MOL File
- Mol file
METFORMIN-D6, HYDROCHLORIDE Property
- Melting point:
- 215-218°C
- storage temp.
- -20°C Freezer
- solubility
- Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 53183
- Product name
- Metformin-(dimethyl-d6) hydrochloride
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $648
- Updated
- 2024/03/01
- Product number
- 16921
- Product name
- Metformin-d6 (hydrochloride)
- Purity
- ≥98% deuterated forms (d1-d6)
- Packaging
- 500μg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 16921
- Product name
- Metformin-d6 (hydrochloride)
- Purity
- ≥98% deuterated forms (d1-d6)
- Packaging
- 1mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 16921
- Product name
- Metformin-d6 (hydrochloride)
- Purity
- ≥98% deuterated forms (d1-d6)
- Packaging
- 5mg
- Price
- $469
- Updated
- 2024/03/01
- Product number
- M3009-75
- Product name
- Metformin-d6, Hydrochloride
- Packaging
- 1mg
- Price
- $382
- Updated
- 2021/12/16
METFORMIN-D6, HYDROCHLORIDE Chemical Properties,Usage,Production
Description
Metformin-d6 is intended for use as an internal standard for the quantification of metformin by GC- or LC-MS. Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day. It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD). Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53-\- human colon cancer mouse xenograft model, but has no effect on HCT116 p53-\- tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I. Formulations containing metformin have been used in the treatment of type 2 diabetes.
Chemical Properties
White Crystalline Solid
Uses
An oral hypoglycemic agent.
METFORMIN-D6, HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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