ChemicalBook > CAS DataBase List > METFORMIN-D6, HYDROCHLORIDE

METFORMIN-D6, HYDROCHLORIDE

Product Name
METFORMIN-D6, HYDROCHLORIDE
CAS No.
1185166-01-1
Chemical Name
METFORMIN-D6, HYDROCHLORIDE
Synonyms
metformin d6;Diabetosan-d6;Metiguanide-d6;Metformine-D6.HCl;Diabex-d6, Glucophage-d6;Metformin Impurity 9 HCl;METFORMIN-D6, HYDROCHLORIDE;Metformin hydrochloride salt;[2H6]-Metformin hydrochloride;1,1-Dimethyl-d6-biguanide HCl
CBNumber
CB8649272
Molecular Formula
C4H6ClD6N5
Formula Weight
171.661550668
MOL File
Mol file
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METFORMIN-D6, HYDROCHLORIDE Property

Melting point:
215-218°C
storage temp. 
-20°C Freezer
solubility 
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
53183
Product name
Metformin-(dimethyl-d6) hydrochloride
Purity
analytical standard
Packaging
5mg
Price
$648
Updated
2024/03/01
Cayman Chemical
Product number
16921
Product name
Metformin-d6 (hydrochloride)
Purity
≥98% deuterated forms (d1-d6)
Packaging
500μg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
16921
Product name
Metformin-d6 (hydrochloride)
Purity
≥98% deuterated forms (d1-d6)
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
16921
Product name
Metformin-d6 (hydrochloride)
Purity
≥98% deuterated forms (d1-d6)
Packaging
5mg
Price
$469
Updated
2024/03/01
Usbiological
Product number
M3009-75
Product name
Metformin-d6, Hydrochloride
Packaging
1mg
Price
$382
Updated
2021/12/16
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METFORMIN-D6, HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Metformin-d6 is intended for use as an internal standard for the quantification of metformin by GC- or LC-MS. Metformin is a biguanide with diverse biological activities. Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice. It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day. It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD). Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53-\- human colon cancer mouse xenograft model, but has no effect on HCT116 p53-\- tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I. Formulations containing metformin have been used in the treatment of type 2 diabetes.

Chemical Properties

White Crystalline Solid

Uses

An oral hypoglycemic agent.

METFORMIN-D6, HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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METFORMIN-D6, HYDROCHLORIDE Suppliers

Canada 2 China 51 India 6 United States 9 Global 68
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
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Alfa Chemistry
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Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
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United States
ProdList
24072
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58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
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Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
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58
Cayman Chemical Company
Tel
--
Fax
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Email
cayman@caymanchem.com
Country
United States
ProdList
6213
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81
MedChemExpress
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sales@medchemexpress.com
Country
United States
ProdList
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Cambridge Isotope Laboratories, Inc.
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cilsales@isotope.com
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United States
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Riedel-de Haen AG
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United States
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Medical Isotopes
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stohler@medicalisotopes.com
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United States
ProdList
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1185166-01-1, METFORMIN-D6, HYDROCHLORIDERelated Search:

Metformin D6

  • Metformin-(dimethyl-d6) hydrochloride
  • Metformine-D6.HCl
  • [2H6]-Metformin hydrochloride
  • 1,1-Di(methyl-d3)biguanide hydrochloride
  • METFORMIN-D6, HYDROCHLORIDE
  • Diabetosan-d6
  • Diabex-d6, Glucophage-d6
  • Metiguanide-d6
  • N,N-Dimethylimidodicarbonimidic Diamide-d6, Hydrochloride
  • 3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine,hydrochloride
  • Metformin-d6 hydrochloride (dimethyl-d6)
  • METFORMIN:HCL (DIMETHYL-D6, 99%)
  • 1,1-Dimethyl-d6-biguanide HCl
  • metformin d6
  • Metformin hydrochloride salt
  • Metformin D6 HydrochlorideQ: What is Metformin D6 Hydrochloride Q: What is the CAS Number of Metformin D6 Hydrochloride Q: What is the storage condition of Metformin D6 Hydrochloride Q: What are the applications of Metformin D6 Hydrochloride
  • Metformin Impurity 9 HCl
  • 1,1-Dimethylbiguanide-d6 hydrochloride
  • N,N-Di(methyl-d3)-imidodicarbonimidic diamide hydrochloride
  • 1185166-01-1
  • 185166-01-1
  • C4H6D6ClN5
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Isotope Labelled Compounds