ChemicalBook > CAS DataBase List > 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE

2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE

Product Name
2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
CAS No.
10581-38-1
Chemical Name
2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
Synonyms
TRIACETONEAMINE HYDRATE;Triacetonamine monohydrate;2,2,6,6-TetraMethyl-4-piperidone Hydrate;2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE;2,2,6,6-Tetramethyl-4-Piperidone/Tripyruvalamine;4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate
CBNumber
CB8663706
Molecular Formula
C9H19NO2
Formula Weight
173.25
MOL File
10581-38-1.mol
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2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Property

Melting point:
59 °C
storage temp. 
Inert atmosphere,2-8°C
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
TSCA 
Yes
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
A16211
Product name
2,2,6,6-Tetramethyl-4-piperidone monohydrate, 99%
Packaging
10g
Price
$29.9
Updated
2023/06/20
Alfa Aesar
Product number
A16211
Product name
2,2,6,6-Tetramethyl-4-piperidone monohydrate, 99%
Packaging
50g
Price
$112.35
Updated
2023/01/06
Alfa Aesar
Product number
A16211
Product name
2,2,6,6-Tetramethyl-4-piperidone monohydrate, 99%
Packaging
250g
Price
$434.7
Updated
2023/01/06
TRC
Product number
T889735
Product name
2,2,6,6-Tetramethyl-4-piperidoneMonohydrate
Packaging
5g
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0007478
Product name
2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
Purity
95.00%
Packaging
5MG
Price
$495.78
Updated
2021/12/16
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2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Chemical Properties,Usage,Production

Uses

Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats[1][2].

in vivo

Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) monohydrate shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality[2].

Animal Model:Rats (half male and female, 6-8 weeks old, 200?±?10 g)[2]
Dosage:200 mg, 300 mg, 400 mg/Kg
Administration:Gavage; daily; 2 days
Result:Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality.

References

[1] Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010;101(11):4242-4245. DOI:10.1016/j.biortech.2010.01.031
[2] Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010 Jun;101(11):4242-5. DOI:10.1016/j.biortech.2010.01.031
[3] Ting Jiang, et al. Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide. Tissue Eng Regen Med. 2022 Apr;19(2):403-415. DOI:10.1007/s13770-021-00421-5

2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Suppliers

China 26 Europe 2 Germany 2 India 1 Japan 1 The Netherlands 1 United Kingdom 3 United States 6 Global 42
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44732
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61
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
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China
ProdList
71829
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Guangzhou Jhd Chemical Reagent Co., Ltd.
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020-84383047
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020-84380294
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sales@jhd.com.cn
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China
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9186
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Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
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China
ProdList
9998
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9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
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60
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
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Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
11695
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58

10581-38-1, 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATERelated Search:

Hexamidine piperidine 3-Methylpiperidin-3-ol HCl 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16-1-OXYL 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-yl tempalgin 1-Benzoyloxy-2,2,6,6-tetramethyl-4-oxopiperidine SPECS AG-690/37009056 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI- 1-ACETYL-2,2,6,6-TETRAMETHYLTETRAHYDRO-4(1H)-PYRIDINONE 4-Oxo-2,2,6,6-tetramethylpiperidinooxy 1-(CHLOROACETYL)-2,2,6,6-TETRAMETHYLPIPERIDIN-4-ONE 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16,1-15N-1-OXYL 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL 1-Acetyloxy-2,2,6,6-tetramethyl-4-oxopiperidine 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE 2,2,6,6-Tetramethylpiperidone-4-toluenesulfonate

  • TRIACETONEAMINE HYDRATE
  • 2,2,6,6-Tetramethyl-4-Piperidone/Tripyruvalamine
  • 4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate
  • 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
  • 2,2,6,6-TetraMethyl-4-piperidone Hydrate
  • Triacetonamine monohydrate
  • 10581-38-1