ChemicalBook > CAS DataBase List > 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE

2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE

Product Name
2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
CAS No.
10581-38-1
Chemical Name
2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
Synonyms
TRIACETONEAMINE HYDRATE;Triacetonamine monohydrate;2,2,6,6-TetraMethyl-4-piperidone Hydrate;2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE;2,2,6,6-Tetramethyl-4-Piperidone/Tripyruvalamine;4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate
CBNumber
CB8663706
Molecular Formula
C9H19NO2
Formula Weight
173.25
MOL File
10581-38-1.mol
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2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Property

Melting point:
59 °C
storage temp. 
Inert atmosphere,2-8°C
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
TSCA 
Yes
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
T889735
Product name
2,2,6,6-Tetramethyl-4-piperidoneMonohydrate
Packaging
5g
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0007478
Product name
2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
Purity
95.00%
Packaging
5MG
Price
$495.78
Updated
2021/12/16
AK Scientific
Product number
J99091
Product name
2,2,6,6-Tetramethyl-4-piperidonemonohydrate
Packaging
25g
Price
$46
Updated
2021/12/16
Ambeed
Product number
A477803
Product name
2,2,6,6-Tetramethyl-4-piperidoneHydrate
Purity
98+%
Packaging
500g
Price
$49
Updated
2021/12/16
Ambeed
Product number
A477803
Product name
2,2,6,6-Tetramethyl-4-piperidoneHydrate
Purity
98+%
Packaging
25g
Price
$9
Updated
2021/12/16
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2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Chemical Properties,Usage,Production

Uses

Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats[1][2].

in vivo

Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) monohydrate shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality[2].

Animal Model:Rats (half male and female, 6-8 weeks old, 200?±?10 g)[2]
Dosage:200 mg, 300 mg, 400 mg/Kg
Administration:Gavage; daily; 2 days
Result:Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality.

References

[1] Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010;101(11):4242-4245. DOI:10.1016/j.biortech.2010.01.031
[2] Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010 Jun;101(11):4242-5. DOI:10.1016/j.biortech.2010.01.031
[3] Ting Jiang, et al. Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide. Tissue Eng Regen Med. 2022 Apr;19(2):403-415. DOI:10.1007/s13770-021-00421-5

2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE Suppliers

China 27 Europe 2 Germany 2 India 1 Japan 1 The Netherlands 1 United Kingdom 3 United States 6 Global 43
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

10581-38-1, 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATERelated Search:

Hexamidine piperidine 3-Methylpiperidin-3-ol HCl 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16-1-OXYL 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-yl tempalgin 1-Benzoyloxy-2,2,6,6-tetramethyl-4-oxopiperidine SPECS AG-690/37009056 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI- 1-ACETYL-2,2,6,6-TETRAMETHYLTETRAHYDRO-4(1H)-PYRIDINONE 4-Oxo-2,2,6,6-tetramethylpiperidinooxy 1-(CHLOROACETYL)-2,2,6,6-TETRAMETHYLPIPERIDIN-4-ONE 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-D16,1-15N-1-OXYL 4-OXO-2,2,6,6-TETRAMETHYLPIPERIDINE-1-15N-1-OXYL 1-Acetyloxy-2,2,6,6-tetramethyl-4-oxopiperidine 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE 2,2,6,6-Tetramethylpiperidone-4-toluenesulfonate

  • TRIACETONEAMINE HYDRATE
  • 2,2,6,6-Tetramethyl-4-Piperidone/Tripyruvalamine
  • 4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate
  • 2,2,6,6-TETRAMETHYL-4-PIPERIDONE MONOHYDRATE
  • 2,2,6,6-TetraMethyl-4-piperidone Hydrate
  • Triacetonamine monohydrate
  • 10581-38-1