ChemicalBook > CAS DataBase List > 1-Ethyl-2-pyrrolidone

1-Ethyl-2-pyrrolidone

Product Name
1-Ethyl-2-pyrrolidone
CAS No.
2687-91-4
Chemical Name
1-Ethyl-2-pyrrolidone
Synonyms
1-ETHYL-2-PYRROLIDINONE;N-Ethylpyrrolidone;N-Ethylpyrrolidinone;1-ETHYL-2-PYRROLIDONE;N-Ethyl-2-pyrrolidone (NEP);DDR;NEP crystal;N-Ethyl-2-pyrrolidinone;CAK;DDR1
CBNumber
CB8666318
Molecular Formula
C6H11NO
Formula Weight
113.16
MOL File
2687-91-4.mol
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1-Ethyl-2-pyrrolidone Property

Melting point:
87.5-88.5 °C
Boiling point:
97 °C/20 mmHg (lit.)
Density 
0.992 g/mL at 25 °C (lit.)
vapor pressure 
18Pa at 20℃
refractive index 
n20/D 1.465(lit.)
Flash point:
169 °F
storage temp. 
Sealed in dry,Room Temperature
pka
-0.41±0.20(Predicted)
form 
Liquid
color 
Clear
PH
8-9 (100g/l, H2O, 20℃)
explosive limit
1.3-7.7%(V)
biological source
rabbit
Water Solubility 
1000g/L at 23℃
BRN 
107971
Specific Activity
4.25-5.75nmol/min·mg
InChIKey
ZFPGARUNNKGOBB-UHFFFAOYSA-N
LogP
-0.2 at 20℃
Surface tension
36.5mN/m at 293.15K
CAS DataBase Reference
2687-91-4(CAS DataBase Reference)
NIST Chemistry Reference
1-Ethyl-2-pyrrolidinone(2687-91-4)
EPA Substance Registry System
2-Pyrrolidinone, 1-ethyl- (2687-91-4)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
22-36-62-41-61
Safety Statements 
26-36-45-36/37/39-53
RIDADR 
UN1993
WGK Germany 
1
RTECS 
UY5769250
Autoignition Temperature
245°C (DIN 51794)
TSCA 
Yes
HazardClass 
3
HS Code 
29337900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP5020
Product name
DDR1 (444-end), active, GST tagged human
Purity
PRECISIO<SUP>&#174;</SUP> Kinase, recombinant, expressed in baculovirus infected <I>Sf</I>9 cells, &#8805;70% (SDS-PAGE), buffered aqueous glycerol solution
Packaging
10 μg
Price
$416
Updated
2025/07/31
Sigma-Aldrich
Product number
SAB2900058
Product name
Anti-DDR1 (AB1) antibody produced in rabbit
Purity
affinity isolated antibody, buffered aqueous solution
Packaging
50μG
Price
$725
Updated
2025/07/31
Sigma-Aldrich
Product number
8.42196
Product name
1-Ethyl-2-pyrrolidinone
Purity
for synthesis
Packaging
25 mL
Price
$73.8
Updated
2025/07/31
Sigma-Aldrich
Product number
146358
Product name
1-Ethyl-2-pyrrolidone
Purity
98%
Packaging
100g
Price
$136
Updated
2025/07/31
Sigma-Aldrich
Product number
146358
Product name
1-Ethyl-2-pyrrolidone
Purity
98%
Packaging
500g
Price
$469
Updated
2025/07/31
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1-Ethyl-2-pyrrolidone Chemical Properties,Usage,Production

Chemical Properties

N-Ethyl-2-pyrrolidone (NEP) is a colorless, clear liquid that serves as a low-volatility aprotic solvent classified as a reproductive toxicant. It is characterized by high solvency, low vapor pressure, and a low dielectric constant.

Uses

1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring.

Application

N-Ethyl-2-pyrrolidone is commonly used as a solvent. It has a low boiling point, which makes it suitable for use in low light and at constant pressure. It is also used as an intermediate in the preparation of polycarboxylic acid. It has been shown to be involved in both viscosity and hydrogen bonding.

Definition

ChEBI: 1-Ethyl-2-pyrrolidinone is a N-alkylpyrrolidine.

General Description

1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.

Flammability and Explosibility

Non flammable

Biological Activity

CDK7 gene is a member of the cyclin-dependent protein kinase family th at is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH th at is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Side effects

Neurotoxins - Acute Solvent Syndrome
Occupational Hepatotoxin - Secondary Hepatotoxin: Cases of possible toxic effects in an occupational setting depending on human ingestion or experimental poisoning of animals.
Reproductive toxin - A chemical that is toxic to the reproductive system, including offspring defects and damage to male or female reproductive function. Reproductive toxicity includes developmental effects.

Safety Profile

Moderately toxic by ingestion. An eye irritant. Combustible. When heated to decomposition it emits toxic fumes of NOx.

Toxics Screening Level

The initial threshold screening level (ITSL) for 1-ethyl-2-pyrrolidone (CAS # 2687-91-4) is 4.9 μg/m3 based on an annual averaging time.

1-Ethyl-2-pyrrolidone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Ethyl-2-pyrrolidone Suppliers

Americas 1 Belgium 5 Canada 1 China 427 Czech Republic 1 Europe 2 France 3 Germany 11 India 17 Italy 1 Japan 4 Slovakia 1 South Korea 2 Spain 1 Switzerland 2 The Netherlands 3 Turkey 1 United Kingdom 12 United States 37 Global 532
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View Lastest Price from 1-Ethyl-2-pyrrolidone manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
N-Ethyl-2-pyrrolidone 2687-91-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-12-04
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
N-Ethyl-2-pyrrolidone 2687-91-4
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Month
Release date
2024-04-29
Qingdao RENAS Polymer Material Co., Ltd.
Product
N-ethyl-2-Pyrrolidinone 2687-91-4
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2025-03-24

2687-91-4, 1-Ethyl-2-pyrrolidoneRelated Search:

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