ChemicalBook > CAS DataBase List > CGP 52432

CGP 52432

Product Name
CGP 52432
CAS No.
139667-74-6
Chemical Name
CGP 52432
Synonyms
P52432;CGP 52432;CGP52432 >=98% (HPLC);CGP 52432;CGP-52432;CGP 52432;(3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid;3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-;Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor
CBNumber
CB8669551
Molecular Formula
C15H24Cl2NO4P
Formula Weight
384.24
MOL File
139667-74-6.mol
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CGP 52432 Property

Boiling point:
544.4±50.0 °C(Predicted)
Density 
1.258±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: soluble1mg/mL, clear (warmed)
form 
powder
pka
2.26±0.50(Predicted)
color 
white to beige
Water Solubility 
Soluble in water (10mM, gentle warming)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0593
Product name
CGP52432
Purity
≥98% (HPLC)
Packaging
5mg
Price
$134
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0593
Product name
CGP52432
Purity
≥98% (HPLC)
Packaging
25mg
Price
$539
Updated
2024/03/01
Cayman Chemical
Product number
27212
Product name
CGP 52432
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
27212
Product name
CGP 52432
Packaging
50mg
Price
$841
Updated
2024/03/01
Cayman Chemical
Product number
27212
Product name
CGP 52432
Packaging
10mg
Price
$207
Updated
2024/03/01
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CGP 52432 Chemical Properties,Usage,Production

Uses

CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:

  • to study its effects on the simulation of the onset of status epilepticus (SE) in mice
  • for voltage-clamp recording in mice neurons
  • to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus

Definition

ChEBI: 3-[(3,4-dichlorophenyl)methylamino]propyl-(diethoxymethyl)phosphinic acid is a dichlorobenzene.

Biological Activity

Potent, selective GABA B receptor antagonist (IC 50 = 85 nM).

Biochem/physiol Actions

CGP52432 participates in inhibiting the glycine overflow in the hippocampus.

storage

+4°C (desiccate)

CGP 52432 Preparation Products And Raw materials

Raw materials

Preparation Products

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CGP 52432 Suppliers

China 52 Germany 2 India 1 Japan 1 United Kingdom 3 United States 12 Global 71
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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Tianjin Kailiqi Biotechnology Co., Ltd.
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Henan Alfachem Co.,Ltd.
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Energy Chemical
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ChemeGen 中国
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View Lastest Price from CGP 52432 manufacturers

Career Henan Chemical Co
Product
CGP 52432 139667-74-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

139667-74-6, CGP 52432Related Search:

BENZYL ISOTHIOCYANATE Methylene dithiocyanate TRIMETHYLSILYL ISOTHIOCYANATE Hypophosphorous acid CGP 35348 CGP 52432 3-AMINOPROPYL(METHYL)PHOSPHINIC ACID HCL

  • 3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID
  • CGP 52432
  • CGP 52432;CGP-52432;CGP 52432
  • P52432
  • Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-
  • CGP52432 >=98% (HPLC)
  • (3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid
  • Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor
  • 139667-74-6
  • C15H24Cl2NO4P
  • GABA/Glycine receptor
  • GABA